Results 71 to 80 of about 5,427 (217)

Inhaler Competence and Patient Satisfaction with Easyhaler: Results of Two Real-Life Multicentre Studies in Asthma and COPD. [PDF]

, 2013
OBJECTIVE: The aim of this study was to investigate patients' inhaler competence and satisfaction with the Easyhaler(R) dry powder inhaler. DESIGN: Two open, uncontrolled, non-randomised studies.
Gabriella Gálffy, Gyula Németh, Györgyi Mezei, Lilla Tamási, Marta Orosz, Olof Selroos, Veronika Müller   +6 more
core   +2 more sources

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Avaliação do conhecimento sobre o uso de inaladores dosimetrados entre profissionais de saúde de um hospital pediátrico Evaluation of the knowledge of health professionals at a pediatric hospital regarding the use of metered-dose inhalers

Jornal Brasileiro de Pneumologia, 2008
OBJETIVO: Avaliar os conhecimentos sobre o uso e manejo de inaladores pressurizados dosimetrados entre profissionais de um hospital pediátrico terciário.
Fábio Pereira Muchão, Sílvia La Regina Rodrigues Perín, Joaquim Carlos Rodrigues, Cláudio Leone, Luiz Vicente Ribeiro Ferreira Silva Filho   +4 more
doaj   +1 more source

Characterization of a Human Powered Nebulizer Compressor for Resource Poor Settings [PDF]

, 2014
Background Respiratory disease accounts for three of the ten leading causes of death worldwide. Many of these diseases can be treated and diagnosed using a nebulizer. Nebulizers can also be used to safely and efficiently deliver vaccines.
Hallberg, Christopher J., Kopesky, William K., Lysaught, Mary Therese, Olson, Lars E., Zmudka, Christopher E.   +4 more
core   +2 more sources

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Hydrogen Halide Gas Sensors: Active Materials, Operation Principles, and Emerging Technologies

Interdisciplinary Materials, EarlyView.
This review considers hydrogen halide (HX) gas sensors across functional materials and principles: acoustic, chemical, optical and nanophotonic. The strong acidity and reactivity of HX gases are discussed as constraints for stability and selectivity of these devices.
Xiuzhen Liu, Nikita Tukachev, Kehang Wang, Dmirty Zhirihin, Yaopeng Cheng, Pavel Krasnov, Mingzhao Song, Soslan Khubezhov, Wenping Yin, Emmanuel Stratakis, Sailing He, Andrey L. Rogach, Sergey Makarov   +12 more
wiley   +1 more source

Integrating evidence for managing asthma in patients who smoke [PDF]

, 2014
Peer reviewedPublisher ...
Bjermer, Leif, Chisholm, Alison, Popov, Todor A, Price, David   +3 more
core   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Dispersion and Characterization of Pharmaceutical Dry Powder Aerosols

KONA Powder and Particle Journal, 2014
Dry powder inhalers may be employed for the delivery of drugs to the lungs for the treatment of pulmonary and systemic diseases. Dry powder inhalers consist of a formulation, metering system and delivery device.
Craig A. Dunber, Anthony J. Hickey, Peter Holzner   +2 more
doaj   +1 more source