Results 111 to 120 of about 223,349 (294)
Chinese expert consensus statement on metformin in clinical practice
Chinese Medical Journal, 2020 Expert Group of Metformin in Clinical Practice +1 more
doaj +1 more source
Journal of Diabetes Research, 2018 Metformin is considered the first-line treatment for type 2 diabetes. While metformin primarily increases insulin sensitivity, evidence also suggests that metformin affects the activity of insulin-secreting pancreatic islets.
Lindor Gelin +4 more
doaj +1 more source
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Metformin-Induced Mitochondrial Complex I Inhibition: Facts, Uncertainties, and Consequences
Frontiers in Endocrinology, 2018 Metformin is the most widely prescribed drug to treat patients with type II diabetes, for whom retrospective studies suggest that metformin may have anticancer properties.
Eric Fontaine
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu +9 more
wiley +1 more source
A Case of Venous Tissue Dissection During Transcatheter MitraClip Surgery
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT The MitraClip system has been widely used to treat mitral regurgitation. The complications associated with MitraClip surgery typically include clip detachment and mitral valve injury. However, cases of venous tissue dissection during surgery are relatively rare.
Shumin Ouyang +5 more
wiley +1 more source
OCT1-Mediated Metformin Uptake Regulates Pancreatic Stellate Cell Activity
Cellular Physiology and Biochemistry, 2018 Background/Aims: Metformin treatment is reported to be associated with a lower incidence of and mortality from pancreatic cancer (PC) in type 2 diabetes patients.
Chunhua Wu +4 more
doaj +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Feature importance for predicting multiple diabetes complications based on a Stacking‐Classifier Chain model. Abstract Background Type 2 diabetes mellitus (T2DM) leads to severe microvascular and macrovascular complications. Traditional single‐label prediction models fail to capture their co‐occurring nature.
Maryam Zamani +3 more
wiley +1 more source
PLoS ONE, 2016 Observational studies have demonstrated that metformin use in diabetic patients is associated with reduced cancer incidence and mortality. Here, we aimed to determine whether metformin use was associated with improved survival in patients with resected ...
Chenwi M Ambe +4 more
doaj +1 more source
Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development. [PDF]
, 2019 Pancreatic ductal adenocarcinoma (PDAC) remains a deadly disease with no efficacious treatment options. PDAC incidence is projected to increase, which may be caused at least partially by the obesity epidemic.
Eibl, Guido, Rozengurt, Enrique
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