Results 1 to 10 of about 726,838 (122)

The crystal structure of methacholine chloride, C₈H₁₈ClNO₂ [PDF]

Zeitschrift für Kristallographie - New Crystal Structures, 2021
Abstract C8H18ClNO2, monoclinic, P21/c (no. 14), a = 6.8110(5) Å, b = 8.8779(7) Å, c = 17.2774(16) Å, β = 97.582(4)°, V = 1035.59(15) Å3, Z = 4, R gt (F) = 0.0484, wR ref (F 2) = 0.0922, T = 200 K.
Kina Muller, Eric C. Hosten, Richard Betz   +2 more
semanticscholar   +3 more sources

Comparing the inhalation of methacholine chloride and methacholine for methacholine challenge testing. [PDF]

Eur J Med Res
Bronchial challenge testing with methacholine was applied to evaluate and quantify bronchial hyperresponsiveness (BHR) in asthma patients. We aimed to compare the clinical effectiveness between methacholine chloride and methacholine for methacholine ...
Chen M, Shen B, Feng P, Wu Y, Huang G.
europepmc   +3 more sources

Effect of a Single Dose Montelukast Sodium on Methacholine Chloride PC₂₀ [PDF]

Canadian Respiratory Journal, 2005
BACKGROUND: It is currently recommended that leukotriene modifiers (receptor antagonists and synthesis inhibitors) be withheld for a minimum of 24 h before direct bronchoprovocation testing, but there is little evidence to support this recommendation.OBJECTIVE: To examine the effect of a single oral dose of montelukast sodium 10 mg on airway response ...
Beth E Davis, Donald W Cockcroft
semanticscholar   +4 more sources

Acepromazine Reduces Airway Contraction in a Murine Model of Asthma. [PDF]

Clin Exp Pharmacol Physiol
ABSTRACT Acepromazine (ACP) is one of the most used sedatives in veterinary medicine, and its cardiovascular effects are well documented. In contrast, its effects on the respiratory system remain less well understood, particularly in the context of assessment of respiratory mechanics in murine models of asthma, where its use has become more common in ...
Lino-Alvarado A, de Oliveira MA, Serra CSM, Melhado IVS, Campos R, Riffo-Vasquez Y, Moriya HT.   +6 more
europepmc   +2 more sources

Stability of methacholine chloride solutions under different storage conditions over a 9 month period [PDF]

European Respiratory Journal, 1998
Methacholine chloride solutions, routinely used for testing bronchial hyperreactivity, have been shown to degrade over time. The data published addressing the optimal conditions for methacholine chloride storage are conflicting and incomplete. This study investigated the effects of a variety of conditions on the stability of methacholine chloride ...
R D, Hayes, J R, Beach, D M, Rutherford, M R, Sim   +3 more
openaire   +3 more sources

Calibration of bronchial methacholine challenge: addressing dose accuracy and practicality. [PDF]

Eur Clin Respir J
Methacholine bronchial provocation (BMP) is a valuable tool in supporting the diagnosis of asthma, but the BMP must be validated regarding dosing, since the BMP basically is a dose response study.
Madsen F, Hanel B, Mortensen J.
europepmc   +2 more sources

The effects of e-cigarette use on asthma severity in adult BALB/c mice. [PDF]

Exp Physiol
Abstract Electronic cigarettes (e‐cigarettes) are often perceived to be a less harmful alternative to tobacco cigarettes. Potentially due to this perception, they are used by people with pre‐existing respiratory conditions, such as asthma, who otherwise would not smoke. Despite this, there are few studies exploring the health effects of e‐cigarette use
D'abreo JJ, Chivers EK, Noble PB, Berry LJ, Huxley RR, Musk ABW, Franklin PJ, Mullins BJ, Landwehr KR, Larcombe AN.   +9 more
europepmc   +2 more sources

Effect of pH on the stability of methacholine chloride in solution

Respiratory Medicine, 1998
Methacholine chloride bronchoprovocation challenges are performed for the diagnosis and investigation of hyperreactive airways. Over the last 20 yrs various formulations and pH values for the preparation of solutions of methacholine have been described.
Watson, B.L., Cormier, R.A., Harbeck, R.J.   +2 more
openaire   +3 more sources

Stability of methacholine chloride in isotonic sodium chloride using a capillary electrophoresis assay

Journal of Clinical Pharmacy and Therapeutics, 1999
To investigate the stability of methacholine chloride in 0.9% sodium chloride solutions.Methacholine powder was mixed with diluent to a final concentration of 5 and 10 mg/ml. Duplicates of each admixture were divided and stored in glass vials at 25 degrees C, 4 degrees C and -20 degrees C for 12 months.
S, Henn, P, Monfort, J H, Vigneron, M A, Hoffman, M, Hoffman   +4 more
openaire   +3 more sources

Vocal biomarkers correlate with FEV1 variations during methacholine challenge. [PDF]

Clin Transl Allergy
Abstract Background Mobile health applications are increasingly valued for their role in asthma management and the opportunity for large dataset collection. Our study aimed to investigate the feasibility of applying signal‐processing and machine‐learning technologies to detect alterations in the lower airway caliber and develop a machine‐learning ...
Paoletti G, Costanzo G, Merigo M, Puggioni F, Ferri S, Messina MR, Cordella F, Ranieri G, Arienzo A, Savevski V, Canonica GW, de Brito Martins A, Heffler E.   +12 more
europepmc   +2 more sources