Active Principles of Tetradenia riparia; II. Antispasmodic Activity of 8(14), 15-Sandaracopimaradiene-7α, 18-diol [PDF]
Tetradenia riparia is one of the most popular medicinal plants in Rwanda. Previously, several new substances have been isolated from the leaves, including a new diterpenediol, i.e. 8(14),15-sandaracopimaradiene-7α,18-diol. This new diterpenediol exhibits
De Kimpe, Norbert +4 more
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Pharmacology of airway afferent nerve activity [PDF]
Afferent nerves in the airways serve to regulate breathing pattern, cough, and airway autonomic neural tone. Pharmacologic agents that influence afferent nerve activity can be subclassified into compounds that modulate activity by indirect means (e.g ...
Carr Michael J, Undem Bradley J
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The relaxant effect of Ferula assafoetida on smooth muscles and the possible mechanisms [PDF]
Asafoetida (Ferula asafoetida) an oleo-gum-resin belongs to the Apiaceae family which obtained from the living underground rhizome or tap roots of the plant. F.
Boskabady, M.H., Khazdair, M.R.
core
Effects of naphthoquinone on airway responsiveness in the presence or absence of antigen in mice [PDF]
We have recently demonstrated that naphthoquinone (NQ), one of extractable chemical compounds of diesel exhaust particles (DEP), enhances antigen-related airway inflammation with goblet cell hyperplasia in mice (Inoue et al.
Cho Arthur K. +11 more
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Oxidative stress in asthmatic and non-asthmatic adolescent swimmers - a breathomics approach [PDF]
We hypothesize that oxidative stress induced by trichloramine exposure during swimming could be related to etiopathogenesis of asthma among elite swimmers.
Barbosa, C +6 more
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Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat [PDF]
Although angiogenesis is a hallmark feature of asthmatic inflammatory responses, therapeutic anti-angiogenesis interventions have received little attention. Objective: Assess the effectiveness of anti-angiogenic Sn2 lipase-labile prodrugs delivered via α(
Allen, John S +16 more
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Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events [PDF]
An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in previous Cochrane reviews.ObjectivesWe set out to compare the risks of mortality and non-fatal serious adverse events in ...
Altman +18 more
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Quantitative Imaging of Regional Aerosol Deposition, Lung Ventilation and Morphology by Synchrotron Radiation CT [PDF]
To understand the determinants of inhaled aerosol particle distribution and targeting in the lung, knowledge of regional deposition, lung morphology and regional ventilation, is crucial.
Albu, G. +11 more
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Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma [PDF]
Background Exposure to chlorine (Cl2) causes airway injury, characterized by oxidative damage, an influx of inflammatory cells and airway hyperresponsiveness. We hypothesized that Cl2-induced airway injury may be attenuated by antioxidant treatment, even
Toby K McGovern +8 more
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Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma [PDF]
Background While glucocorticoids are currently the most effective therapy for asthma, associated side effects limit enthusiasm for their use. Peroxisome proliferator-activated receptor-γ (PPAR-γ) activators include the synthetic thiazolidinediones (TZDs)
M Wills-Karp +66 more
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