Results 91 to 100 of about 130,679 (320)

The Financial Sustainability of Programs to Initiate Medications for Opioid Use Disorder in Emergency Department Settings

Academic Emergency Medicine, EarlyView.
ABSTRACT Background The US is experiencing an epidemic of opioid misuse and mortality. Effective treatments are available, including medications for opioid use disorders (MOUD), but they are greatly underused due to a variety of barriers. In response, some US hospitals have established programs to identify emergency department (ED) patients with opioid
Dominic Hodgkin, Cindy Parks Thomas, Margot T. Davis, Jennifer J. Wicks, Shelly F. Greenfield, Zachary F. Meisel, Constance M. Horgan   +6 more
wiley   +1 more source

Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]

, 2016
Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M., Kraft, Walter K., Stover, Megan W.   +2 more
core   +2 more sources

Drug Use After Emergency Department‐Initiated Injectable Buprenorphine: A Secondary Analysis of the ED‐INNOVATION Ancillary Safety and Feasibility Trial

Academic Emergency Medicine, EarlyView.
ABSTRACT Study Objective To characterize opioid and nonopioid drug use in the week following emergency department (ED)‐initiated extended‐release buprenorphine (XR‐BUP) treatment using both self‐reported data and urine drug screens (UDS). Methods This study uses data collected during a nonrandomized clinical trial of patients with untreated opioid use ...
Ethan Cowan, Gail D'Onofrio, Jeanmarie Perrone, Erik Anderson, James Dziura, Kathryn Hawk, Andrew Herring, Ryan McCormack, Manali Phadke, Elizabeth A. Samuels, David A. Fiellin   +10 more
wiley   +1 more source

The Electrocardiographic Conundrum in a Patient on Methadone Maintenance Therapy and Cannabis Coingestion: A Case Report of a Heartbreaking Puzzle

Heart Views
Methadone is considered relatively safe when compared to other opioids. Methadone, however, can cause respiratory depression and QT prolongation. Among patients on methadone maintenance therapy, the rate of cannabis use is high.
Muhammad Adnan Zaman, Amna Amir, Lou Mastrine   +2 more
doaj   +1 more source

Methadone Related Poisoning on the Rise in Tehran, Iran [PDF]

Asia Pacific Journal of Medical Toxicology, 2014
Background: In Iran, methadone has been used for methadone maintenance treatment (MMT) as well as analgesic treatment in pain clinics. Recently, there are some reports regarding accidental and intentional methadone poisonings and deaths.
Kambiz Soltaninejad, Hossein Hassanian-Moghaddam, Shahin Shadnia   +2 more
doaj  

Methadone adverse reaction presenting with large increase in plasma methadone binding: a case series

Journal of Medical Case Reports, 2011
Introduction The use of methadone as an analgesic is on the increase, but it is widely recognized that the goal of predictable and reproducible dosing is confounded by considerable variability in methadone pharmacokinetics, and unpredictable side effects
Flockhart David A, Kreutz Yvonne, Zhou Weidong, Lu Wenjie J   +3 more
doaj   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: An open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728] [PDF]

, 2004
BACKGROUND: Heroin is a synthetic opioid with an extensive illicit market leading to large numbers of people becoming addicted. Heroin users often present to community treatment services requesting detoxification and in the UK various agents are used ...
A Ritter, Advisory Council on the Misuse of Drugs, AH Masson, AK Nigam, Charlotte NE Tompkins, Clive E Adams, E Goddard, Great Britain Department of Health, Great Britain Government Statistical Service, Home Office, J Lowinson, J Strang, J Strang, L San, Laura Sheard, LJ Cheskin, M Ramsay, N Linteris, N Seivewright, Nat MJ Wright, Nicola S Oldham, PG O'Connor, Royal Pharmaceutical Society of Great Britain, WK Bickel   +22 more
core   +3 more sources

Hepatitis C virus infection influences the S-methadone metabolite plasma concentration. [PDF]

PLoS ONE, 2013
Heroin-dependent patients typically contract hepatitis C virus (HCV) at a disproportionately high level due to needle exchange. The liver is the primary target organ of HCV infection and also the main organ responsible for drug metabolism.
Shiow-Ling Wu, Sheng-Chang Wang, Hsiao-Hui Tsou, Hsiang-Wei Kuo, Ing-Kang Ho, Sheng-Wen Liu, Ya-Ting Hsu, Yao-Sheng Chang, Yu-Li Liu   +8 more
doaj   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source