Results 91 to 100 of about 49,525 (269)

In silico ordinary differential equation/partial differential equation hemodialysis model estimates methadone removal during dialysis

Journal of Pain Research, 2015
Oscar A Linares,1 William E Schiesser,2 Jeffrey Fudin,3–6 Thien C Pham,6 Jeffrey J Bettinger,6 Roy O Mathew,6 Annemarie L Daly7 1Translational Genomic Medicine Lab, Plymouth Pharmacokinetic Modeling Study Group, Plymouth, MI, 2Department of ...
Linares OA, Schiesser WE, Fudin J, Pham TC, Bettinger JJ, Mathew RO, Daly AL   +6 more
doaj  

Negative Direct Coombs’ Tests in Narcotic Addicts Receiving Maintenance Doses of Methadone [PDF]

, 1972
Geoffrey K. Sherwood, Mary H. McGinniss, Richard N. Katon, Robert L. DuPont, Joseph B. Webster   +4 more
openalex   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Methadone: Antimicrobial Activity and Interaction with Antibiotics [PDF]

, 1977
John N. Sheagren, I. S. Barsoum, Melody Y. C. Lin   +2 more
openalex   +1 more source

A GLP‐1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl‐evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Emerging literature indicates that simultaneously targeting glucagon‐like peptide‐1 receptors (GLP‐1Rs) and neuropeptide Y receptors (Y1/Y2) may represent a new pharmacotherapeutic approach to treating opioid use disorder (OUD).
Antonia Caffrey, Enzo Lavecchia, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt   +5 more
wiley   +1 more source

Opioid receptors in cardiovascular function

British Journal of Pharmacology, EarlyView.
Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari, Kesha K. Dalal, Narendra Kondapalli, Sailaja Paruchuri, Charles K. Thodeti   +4 more
wiley   +1 more source

LETHAL AND SUBLETHAL EFFECTS ON THE PROGENY OF MALE RATS TREATED WITH METHADONE [PDF]

, 1977
Lester F. Soyka, John M. Peterson, Justin M. Joffe   +2 more
openalex   +1 more source

Biallelic FGF4 Variants Linked to Thoracic Dystrophy and Respiratory Insufficiency

Clinical Genetics, EarlyView.
We report three people from two unrelated families with a clinical diagnosis of thoracic dystrophy characterized by short or missing ribs, narrow chest, and respiratory insufficiency. Affected people each have rare, biallelic, predicted deleterious missense substitutions in FGF4, a gene known to be essential for the formation of the thoracic skeleton ...
Laura M. Watts, Esther Kinning, Donald R. Latner, Marla Johnston, Jessica Patrick‐Esteve, Gregory M. Cooper, Stephen R. F. Twigg, Alistair T. Pagnamenta, Jenny C. Taylor   +8 more
wiley   +1 more source

METHADONE WITHDRAWAL IN NEONATES [PDF]

, 1974
Fariborz Rahbar, Melvin E. Jenkins
openalex   +1 more source

Clinicians' Perspectives on Cannabis Use and Cannabis Treatment in Clients Undertaking Opioid Dependence Treatment

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction There are no prior studies investigating the perspectives of Opioid Treatment Program (OTP) clinicians on clients' cannabis use. This study examines the perspectives of OTP clinicians on patterns of cannabis use; harms and benefits; current and potential interventions and their confidence in implementing them.
Laila Parvaresh, Llewellyn Mills, Jaleh Gholami, Louisa Jansen, Nazila Jamshidi, Kate Baker, Christopher Tremonti, Marguerite Tracy, Adrian Dunlop, Nicholas Lintzeris   +9 more
wiley   +1 more source