Results 91 to 100 of about 121,985 (386)
Retrospective analysis of low-dose methadone and QTc prolongation in chronic pain patients [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundMethadone is a synthetic opioid that is widely used for the treatment of chronic pain. The association between methadone treatment and QT interval prolongation or which can lead to torsades de pointes has been confirmed with larger studies on ...
Billy Huh, Chan-Hong Park
doaj +1 more source
Drug Testing and Analysis, EarlyView.Among 23,900 urine and oral fluid drug tests from Swedish workplaces, 4.6% tested positive for controlled substances. Cannabis, amphetamine, cocaine and benzodiazepines were most common. Many samples containing opiates, amphetamine or benzodiazepines were MRO verified as being due to medical prescriptions, while cannabis or cocaine were almost entirely
Anders Helander, Fredrik Sparring
wiley +1 more source
Frontiers in Genetics, 2018 Objective: To explore the association between methadone dosage, plasma drug concentration, SNPs of μ-opioid receptor gene (OPRM1), ATP-binding cassette subfamily B member 1 gene (ABCB1), and methadone maintenance treatment (MMT) response.Method: A total ...
Sufang Peng +8 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean‐up is obtained by parallel artificial liquid membrane extraction and analyzed by liquid chromatography–tandem mass spectrometry.
Martina Croce +6 more
wiley +1 more source
Methadone adverse reaction presenting with large increase in plasma methadone binding: a case series
Journal of Medical Case Reports, 2011 Introduction The use of methadone as an analgesic is on the increase, but it is widely recognized that the goal of predictable and reproducible dosing is confounded by considerable variability in methadone pharmacokinetics, and unpredictable side effects
Flockhart David A +3 more
doaj +1 more source
Problematisation and regulation: bodies, risk, and recovery within the context of Neonatal Abstinence Syndrome [PDF]
, 2018 Background Neonatal Abstinence Syndrome (NAS) is an anticipated effect of maternal drug use during pregnancy. Yet it remains a contested area of policy and practice.
Chandler, Amy +5 more
core +3 more sources
Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024
ELECTROPHORESIS, EarlyView.ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley +1 more source
Hepatitis C virus infection influences the S-methadone metabolite plasma concentration. [PDF]
PLoS ONE, 2013 Heroin-dependent patients typically contract hepatitis C virus (HCV) at a disproportionately high level due to needle exchange. The liver is the primary target organ of HCV infection and also the main organ responsible for drug metabolism.
Shiow-Ling Wu +8 more
doaj +1 more source
Service providers' adherence to methadone maintenance treatment protocol in China. [PDF]
, 2018 BACKGROUND:Methadone maintenance treatment (MMT) programs have expanded rapidly in China during the last decade. However, variance in service providers' practice may have an impact on the quality of care received by the patients.
Lan, Chiao-Wen +3 more
core +2 more sources
Methadone for neuropathic pain in adults.
Cochrane Database of Systematic Reviews, 2017 BACKGROUND This review replaces an earlier review, "Methadone for chronic non-cancer pain in adults". This review serves to update the original and includes only studies of neuropathic pain.
E. McNicol +2 more
semanticscholar +1 more source