Results 111 to 120 of about 102,331 (342)

Effect of Methadone on Cardiac Repolarization in Japanese Cancer Patients: A Longitudinal Study

Cardiology and Therapy, 2019
Introduction Methadone is known to prolong the QT interval, which could induce lethal arrhythmias such as torsades de pointes. To determine the risk of ventricular arrhythmias in cancer patients using methadone, we measured QT dispersion (QTD) and Tpeak ...
Eriko Yamanaka, Satoru Chino, Toshifumi Takasusuki, Shinsuke Hamaguchi, Shigeki Yamaguchi   +4 more
doaj   +1 more source

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. [PDF]

, 2018
The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Livingston, Kathryn E, Mahoney, Jacob P, Manglik, Aashish, Sunahara, Roger K, Traynor, John R   +4 more
core  

The effectiveness of Individual Placement and Support on vocational outcomes for patients with substance use disorders: A pragmatic superiority randomized controlled trial of Individual Placement and Support versus enhanced self‐help

Addiction, EarlyView.
Abstract Background and aim Unemployment rates among individuals with substance use disorders (SUD) are high, and evidence‐based vocational methods are lacking. Employment is important because it improves treatment outcomes and protects against relapse.
Eline Borger Rognli, Kristoffer Andreas Aamodt Andersen, Erlend Marius Aas, Silje Endresen Reme, June Ullevoldsæter Lystad, Marianne Riksheim Stavseth, Espen Ajo Arnevik   +6 more
wiley   +1 more source

Crystal Structures of Synthetic Analgetics. II. l-Methadone. [PDF]

, 1974
Erik Bye, Svend Treppendahl, Carsten Christophersen, Gustav Schroll, A. Taticchi, Bengt Mannervik   +5 more
openalex   +1 more source

Comparative effectiveness of urine drug testing schedules alongside opioid agonist treatment: Emulation of a population‐based target trial in British Columbia, Canada

Addiction, EarlyView.
Abstract Background and aim Urine drug testing is often utilized alongside opioid agonist treatment to assess client progress by validating self‐reported substance use, monitoring for diversion and supporting clinical decisions for take‐home dosing. However, there is a paucity of evidence to support the practice of urine drug testing.
Megan Kurz, Brenda Carolina Guerra‐Alejos, Jeong Eun Min, Shaun R. Seaman, Micah Piske, Paxton Bach, Julie Bruneau, Sander Greenland, Paul Gustafson, Kyle Kampman, Mohammad Ehsanul Karim, P. Todd Korthuis, Robert W. Platt, Uwe Siebert, M. Eugenia Socías, Evan Wood, Bohdan Nosyk   +16 more
wiley   +1 more source

Cardiovascular Complications Following Acute Methadone Poisoning in Patients with and Without a History of Long-term Methadone Use

Journal of Research in Pharmacy Practice
Objective: Given the prevalence of methadone poisoning, this study was conducted to compare the cardiovascular complications following acute methadone poisoning in patients with and without a history of long-term methadone use.
Gholamali Dorooshi, Mahbod Shirmohammadi, Farzad Gheshlaghi, Arman Otroshi, Shafeajafar Zoofaghari, Nastaran Eizadi-Mood   +5 more
doaj   +1 more source

Methadone: Antimicrobial Activity and Interaction with Antibiotics [PDF]

, 1977
John N. Sheagren, I. S. Barsoum, Melody Y. C. Lin   +2 more
openalex   +1 more source

Counterfeit ‘Xanax®’ tablets: A comparative study of clinical and seizure data in Victoria, Australia

Addiction, EarlyView.
Abstract Background and aim There is growing evidence of counterfeit benzodiazepine products containing other substances, including non‐regulated benzodiazepine‐type new psychoactive substances (NPSs). This study sought to compare detections of seized suspect counterfeit alprazolam products with clinical cases that reported use of an alprazolam ...
Rebekka Syrjanen, Shaun L. Greene, Sarah E. Hodgson, Rachelle Abouchedid, Dimitri Gerostamoulos, Christie Magee, Melissa Bremner, Jennifer L. Schumann, on behalf of the Emerging Drugs Network of Australia – Victoria (EDNAV) research group   +8 more
wiley   +1 more source

Qualitative analysis of barriers and facilitators to healthcare engagement for people with injecting‐related invasive infections using a social ecological framework

Addiction, EarlyView.
Abstract Background and aims Injecting‐related bacterial infections are increasing in many countries. Systemic infections often require prolonged treatment. Evidence suggests that people who inject drugs who have invasive infections are less likely to complete antimicrobial treatment and have poorer outcomes than patients without a history of injecting
Lucy O. Attwood, Sophia E. Schroeder, Olga Vujovic, Andrew J. Stewardson, Joseph S. Doyle, Paul Dietze, Peter Higgs, Samantha Colledge‐Frisby   +7 more
wiley   +1 more source

Thin-layer Chromatography and Enzyme Immunoassay of L-Alpha-Acetyl Methadol and Methadone Metabolites in Urine [PDF]

, 1975
Joyce A. McIntyre, Arlene E Armandi, Lance P Risen, Walter Ling, George C Haberfeldel   +4 more
openalex   +1 more source