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Results 121 to 130 of about 51,637 (307)

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): short‐term peri‐operative analgesic use

Anaesthesia, EarlyView.
Summary Introduction An increasing proportion of complex surgical procedures are being performed in the UK as day‐cases, with variable and limited follow up. Discharge prescriptions must provide adequate analgesia, while considering the safety of the patient and public, following best practice guidance and good opioid stewardship.
Anna Ratcliffe +2083 more
wiley +1 more source

Novel approaches for the synthesis of R- and S-methadone metabolites, and evaluation of their inhibitory activity against NMDA receptor

, 2022
reservedLa depressione è un disturbo mentale comune caratterizzato da una tristezza grave e persistente che interferisce con le attività quotidiane e diminuisce il normale interesse e il piacere nelle attività.
TODESCHINI, ILEANA
core

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source

Probable sepsis‐associated encephalopathy as a component of multiple organ dysfunction syndrome in a cat with pyothorax

Australian Veterinary Journal, EarlyView.
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source

Cardiac Assessment of Individuals with Opioid Use Disorder under Methadone Treatment

Journal of Research in Pharmacy Practice
Objective: Methadone treatment is effective for managing opioid use disorder (OUD) but raises concerns about its impact on cardiac function. This study aimed to assess the prevalence of cardiac dysfunction among individuals under methadone treatment ...
Hoda Barkhordari +4 more
doaj +1 more source

Insurance coverage and provision of opioid disorder treatment: Evidence from Medicare. [PDF]

J Policy Anal Manage
ABSTRACT Older adult opioid overdose deaths have increased over the past two decades in the United States. Methadone, one of three medications approved for opioid use disorder (OUD) treatment, was not covered by Medicare—the primary insurer of Americans 65 years and older—for OUD until 2020.
Agniel D +4 more
europepmc +2 more sources

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source

'I overdosed twice in two days to get methadone': A drug user on trying to get clean.

, 2016
Heroin users in Galway are intentionally overdosing in an attempt to fast-track their access to methadone.....
Ryan, Orla
core

Looking at a Blind Spot: Using a Longitudinal Population Cohort Study to Examine Inequalities in Child Social Worker Contact Among Mothers Experiencing Domestic Abuse in Scotland

Child &Family Social Work, EarlyView.
ABSTRACT Research on inequalities in children's services in the UK highlights a lack of systematic data on parental demographics, obstructing analysis of structural factors influencing children's outcomes. Using Growing Up in Scotland, a nationally representative longitudinal child cohort study of children born in 2004–2005, we investigate social ...
Valeria Skafida, Eve Mullins, John Devaney +2 more
wiley +1 more source

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