Results 121 to 130 of about 118,303 (321)

An intervention to improve provider-patient interaction at methadone maintenance treatment in China. [PDF]

open access: yes, 2019
BackgroundThis study evaluated an intervention aiming to improve methadone maintenance therapy (MMT) service providers' interaction with their patients in China.MethodsSixty-eight MMT clinics were randomized to either an intervention or a control ...
Cao, Wei   +5 more
core  

Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis.

open access: yesPLoS ONE, 2014
BackgroundGenetic variability may influence methadone metabolism, dose requirements, and risk of relapse.ObjectivesTo determine whether the CYP2B6*6 or ABCB1 (rs1045642) polymorphisms are associated with variation in methadone response (plasma ...
Brittany B Dennis   +4 more
doaj   +1 more source

Survey describing the perspectives and practices of Australian veterinarians to pain management in horses

open access: yesAustralian Veterinary Journal, EarlyView.
Objective To describe Australian practices and attitudes regarding equine analgesia. Study Design Cross‐sectional anonymous, voluntary survey of Australian veterinarians treating equine patients. Methods Australian veterinarians in equine or mixed practices completed a six‐section, 60‐question survey between November 2019 to August 2020.
A Whitelock   +8 more
wiley   +1 more source

Accidental Methadone Toxicity in a 3-Year-Old Leading to Severe Cerebellitis and Death: A Case Report

open access: yesCase Reports in Pediatrics
Methadone is a synthetic opioid used to treat pain and opioid dependence. Despite its benefits, accidental ingestion of methadone in pediatric patients can lead to significant morbidity and mortality.
Jessie Pappin, Greg Hansen, Tanya Holt
doaj   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

Statistical Proof and Theories of Discrimination [PDF]

open access: yes, 1986
We live in a tightly knit world. Our emotions, desires, perceptions and decisions are interlinked in our interactions with others. We are constantly influencing our surroundings and being influenced by others.
Laycock, Douglas
core   +1 more source

Effect of Methadone therapy on QTc interval in electrocardiogram of opioid addicted patients

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Methadone is a synthetic opioid which is used in opium addiction therapy and relief of acute and chronic pain. Side effects of Methadone were reported on heart and induction of Torsade De Pointes disease and increase QTc ...
Shakouri H   +5 more
doaj  

A Case Report of Neuroleptic Malignant Syndrome during Methadone Therapy

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022
Background and Objective: Methadone is an opioid agonist used for the treatment of addiction to opioid drugs. Toxic leukoencephalopathy can cause serious problem and even be life-threatening.
MJ Nasr   +3 more
doaj  

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

From the Mountaintops: What the World Can Learn from Drug Policy Change in Switzerland [PDF]

open access: yes, 2010
Reviews Switzerland's drug policy of policing, prevention, treatment, and harm reduction, including low-threshold methadone programs, needle exchanges, and safe injection rooms.
Csete, Joanne
core  

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