Results 181 to 190 of about 121,985 (386)

Toxicological analyses of the bone matrix: Successes and challenges

Archaeometry, EarlyView.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano, Lucie Biehler‐Gomez, Cristina Cattaneo, Domenico Di Candia   +3 more
wiley   +1 more source

Double Blind Trial of Dextromoramide, Methadone and Pethidine in the Treatment of Severe Pain

, 1964
S. G. Flavell Matts, Caroline Swan, B A Wharton   +2 more
openalex   +1 more source

Methadone Matters: What the United States Can Learn from the Global Effort to Treat Opioid Addiction

Journal of general internal medicine, 2019
S. Calcaterra, P. Bach, A. Chadi, N. Chadi, S. Kimmel, K. Morford, P. Roy, J. Samet   +7 more
semanticscholar   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

CHILDREN EXPOSED TO METHADONE IN-UTERO: COGNITIVE ABILITY IN THE PRESCHOOL YEARS [PDF]

, 1987
Karol Kaltenbach, Loretta P. Finnegan
openalex   +1 more source

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. [PDF]

, 2018
The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Livingston, Kathryn E, Mahoney, Jacob P, Manglik, Aashish, Sunahara, Roger K, Traynor, John R   +4 more
core  

(2R,6R)‐hydroxynorketamine prevents opioid abstinence‐related negative affect and stress‐induced reinstatement in mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder (OUD) is a pressing public health concern marked by frequent relapse during periods of abstinence, perpetuated by negative affective states. Classical antidepressants or the currently prescribed opioid pharmacotherapies have limited efficacy to reverse the negative affect or prevent relapse ...
Andria Michael, Anna Onisiforou, Polymnia Georgiou, Morfeas Koumas, Chris Powels, Elmar Mammadov, Andrea N. Georgiou, Panos Zanos   +7 more
wiley   +1 more source

Accidental ingestion of methadone by children in Merseyside [PDF]

, 1994
James Binchy, E Molyneux, Joseph C. Manning   +2 more
openalex   +1 more source

ESG‐1‐60 and ESG‐1‐61: Novel dopamine D3 receptor‐preferring partial agonists/antagonists that inhibit cocaine taking and seeking in rodents

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño, Bradley M. Keegan, Hannah Alton, Guo‐Hua Bi, Emily Linz, Caleb D. Vogt, Emma S. Gogarnoiu, Lei Shi, Amy Hauck Newman, Zheng‐Xiong Xi   +9 more
wiley   +1 more source

Rx: 3x/week LAAM alternative to methadone.

, 1976
Jack Blaine, Pierre F. Renault
openalex   +2 more sources