Results 11 to 20 of about 89,531 (280)
Background Methadone maintenance therapy (MMT) is a mainstay for treating opioid use disorder and preventing and managing HIV among people who inject drugs (PWID).
Kanna Hayashi +6 more
doaj +1 more source
The search continues for improved therapy for acute lymphoblastic leukemia (aLL), the most common malignancy in children. Recently, d,l-methadone was put forth as sensitizer for aLL chemotherapy.
JungKwon Lee +3 more
doaj +1 more source
Sedative and antinociceptive effects of different combinations of detomidine and methadone in standing horses [PDF]
Objective To evaluate intravenous (IV) detomidine with methadone in horses to identify a combination which provides sedation and antinociception without adverse effects. Study design Randomized, placebo-controlled, blinded, crossover.
Crosignani, N +6 more
core +2 more sources
Toxicological Analysis of Some Drugs of Abuse in Biological Samples [PDF]
Consumption of drugs of abuse is a scourge of modern world. Abuse, drug addiction and their consequences are one of the major current problems of European society because of the significant repercussions in individual, family, social and economic level ...
Baconi, Daniela Luiza +5 more
core +3 more sources
The Effect of CYP2B6, CYP2D6, and CYP3A4 Alleles on Methadone Binding: A Molecular Docking Study
Current methadone maintenance therapy (MMT) is yet to ensure 100% successful treatment as the optimum dosage has yet to be determined. Overdose leads to death while lower dose causes the opioid withdrawal effect.
Nik Nur Syazana Bt Nik Mohamed Kamal +4 more
doaj +1 more source
Methadone maintenance treatment is reported as cost-effective in treatment of opioid use disorder. Estimated cost of providing methadone varies widely in different regions but there is no data regarding cost of methadone treatment in Kenya.
Brenda Mogaka1 +3 more
doaj +1 more source
Maternal methadone use in pregnancy : factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources [PDF]
The objectives of this study were to investigate factors associated with the development of neonatal abstinence syndrome (NAS) and to assess the implications for healthcare resources of infants born to drug-misusing women. Design.
Dryden, C. +3 more
core +1 more source
Harm reduction among injecting drug users - evidence of effectiveness [PDF]
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Goldberg, David +5 more
core +1 more source
Psychopathology and urine toxicology in methadone patients
Several studies reported high rates of psychiatric commorbidity among methadone patients. We examined the relationships of measures of psychopathology to outcomes of screening urine tests for cocaine, opiates, and benzodiazepines in a sample of 56 ...
Gamal Sadek, Zack Cernovsky, Simon Chiu
doaj +1 more source
The challenge of perioperative pain management in opioid-tolerant patients [PDF]
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F +9 more
core +2 more sources

