Results 21 to 30 of about 58,733 (293)

Awareness of the need for safe storage of Methadone at home is not improved by the use of protocols on recording information giving

Harm Reduction Journal, 2008
Background Methadone is a synthetic, narcotic analgesic used in the treatment of drug misuse. Tragedies involving children being poisoned by the accidental ingestion of methadone are no longer a rare occurrence. Following an audit of the effectiveness of
Crome Ilana B, Watts Derrett J, McAuley Rosanna J, Mullin Annemarie, Bloor Roger N   +4 more
doaj   +1 more source

Methadone for prisoners [PDF]

The Lancet, 2016
1 Rich JD, McKenzie M, Larney S, et al. Methadone continuation versus forced withdrawal on incarceration in a combined US prison and jail: a randomised, open-label trial. Lancet 2015; 386: 350–59. 2 Kershnar S. A defense of retributivism. Int J Appl Philos 2000; 14: 97–117. 3 Gewirtz P. Methadone maintenance for heroin addicts.
Daniel, D'Hotman, Jonathan, Pugh, Thomas, Douglas   +2 more
openaire   +4 more sources

Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients - Frequency and correlates of use [PDF]

, 2003
This retrospective study aims to determine whether there is a difference in the additional consumption of alcohol between addicts treated with methadone or dihydrocodeine (DHC) and untreated addicts injecting heroin.
Schütz, Christian G., Backmund, Markus, Soyka, Michael, Eichenlaub, Dieter, Meyer, Kirsten   +4 more
core   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Analysis of Methadone-Related Poisoning Cases

Fayixue Zazhi
ObjectiveTo analyze the characteristics of methadone-related poisoning cases and provide a reference for forensic identification.MethodsA total of 71 cases of methadone-related poisoning reported from 1998 to 2023 in China and 26 cases of methadone ...
LI Ze-qi, XING Lei, ZHANG Hui-ge, HE Li-rou, ZHANG Jia-yi, WANG Jia-qi, LIU Shi-hao, YANG Wei-hong   +7 more
doaj   +1 more source

An ETH‐LAD trip with unfavourable consequences: A case report

British Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler, Michaela Sommer, Annette Zschiesche, Anne Stürzebecher, Christina Grumann, Volker Auwärter, Maren Hermanns‐Clausen   +6 more
wiley   +1 more source

Methadone treatment and patient-directed hospital discharges among patients with opioid use disorder: Observations from general medicine services at an urban, safety-net hospital

Drug and Alcohol Dependence Reports, 2022
Introduction: People with opioid use disorder (OUD) have high rates of discharge against medical advice from the hospital. Interventions for addressing these patient-directed discharges (PDDs) are lacking.
Hannah R. Tierney, Christopher L. Rowe, Diana A. Coffa, Shashi Sarnaik, Phillip O. Coffin, Hannah R. Snyder   +5 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Rapid Methadone Metabolism in Opioid Use Disorder: A Case Report of Clinical Challenges and Individualized Treatment Approaches

Reports
Rapid methadone metabolism in patients with opioid use disorder could complicate methadone treatment. Toxicology screenings to monitor methadone levels may show negative for methadone, even with regular adherence to a regimen.
Farhana Nazmin, Jaskaran Singh, Narges Joshaghani, Elisio Go   +3 more
doaj   +1 more source

Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

Molecular Pain, 2016
Background Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts ...
Seira Doi BS, Tomohisa Mori PhD, Naoki Uzawa MS, Takamichi Arima BA, Tomoyuki Takahashi BA, Masashi Uchida BS, Ayaka Yawata BA, Michiko Narita BS, Yasuhito Uezono PhD, Tsutomu Suzuki PhD, Minoru Narita PhD   +10 more
doaj   +1 more source