Results 31 to 40 of about 89,531 (280)

Methadone treatment and patient-directed hospital discharges among patients with opioid use disorder: Observations from general medicine services at an urban, safety-net hospital

open access: yesDrug and Alcohol Dependence Reports, 2022
Introduction: People with opioid use disorder (OUD) have high rates of discharge against medical advice from the hospital. Interventions for addressing these patient-directed discharges (PDDs) are lacking.
Hannah R. Tierney   +5 more
doaj   +1 more source

Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice [PDF]

open access: yes
Type 1 diabetes is an autoimmune disease characterized by inflammation of pancreatic islets and destruction of β cells by the immune system. Opioids have been shown to modulate a number of immune functions, including T helper 1 (Th1) and T helper 2 ...
امیرشاهرخی, کیوان   +4 more
core   +1 more source

Analysis of Methadone-Related Poisoning Cases

open access: yesFayixue Zazhi
ObjectiveTo analyze the characteristics of methadone-related poisoning cases and provide a reference for forensic identification.MethodsA total of 71 cases of methadone-related poisoning reported from 1998 to 2023 in China and 26 cases of methadone ...
LI Ze-qi   +7 more
doaj   +1 more source

Intraoperative Methadone Use in Patients Undergoing Minimally Invasive Colorectal Surgical Procedures

open access: yesWorld Journal of Colorectal Surgery, 2023
Background: Postoperative pain control is an important aspect in the recovery of patients. Recent literature suggests that the extended half-life of methadone may reduce overall opioid utilization in postoperative patients.
Nathan S Kau
doaj   +1 more source

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

open access: yes, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S.   +2 more
core  

Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]

open access: yes, 2011
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter   +5 more
core   +2 more sources

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins   +23 more
wiley   +1 more source

Problematisation and regulation: bodies, risk, and recovery within the context of Neonatal Abstinence Syndrome [PDF]

open access: yes, 2018
Background Neonatal Abstinence Syndrome (NAS) is an anticipated effect of maternal drug use during pregnancy. Yet it remains a contested area of policy and practice.
Chandler, Amy   +5 more
core   +3 more sources

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis   +5 more
wiley   +1 more source

Job Satisfaction Among Methadone Maintenance Treatment Clinic Service Providers in Jiangsu, China: A Cross-sectional Survey. [PDF]

open access: yes, 2020
ObjectiveService providers' job satisfaction is critical to the stability of the work force and thereby the effectiveness of methadone maintenance treatment (MMT) programs.
Cao, Xiaobin   +9 more
core  

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