Results 51 to 60 of about 58,733 (293)

The relationship between methadone dosage and plasma level changes with aging in methadone maintenance treatment (MMT) patients

Substance Abuse Treatment, Prevention, and Policy
Background As aging is associated with physiological changes, patients in methadone maintenance treatment (MMT) may require an adequate methadone dose adjustment.
Anat Sason, Miriam Adelson, Shaul Schreiber, Einat Peles   +3 more
doaj   +1 more source

Magnesium Salt, a Simple Strategy to Improve Methadone Analgesia in Chronic Pain: An Isobolographic Preclinical Study in Neuropathic Mice

Frontiers in Pharmacology, 2020
Analgesic efficacy of methadone in cancer and chronic non-cancer pains is greater than that of other opioids, probably because of its unique pharmacokinetics properties and also because it targets glutamatergic receptors in addition to µ-opioid receptors.
Valeria González, Teresa Pelissier, Victoria Cazanga, Alejandro Hernández, Luis Constandil, Luis Constandil   +5 more
doaj   +1 more source

Single‐dose enflicoxib versus a 7‐day course of firocoxib for postoperative pain control in dogs undergoing orthopaedic surgery: A multicentre, randomised, masked, non‐inferiority study

Veterinary Record, EarlyView.
Abstract Background Perioperative analgesia is essential in dogs undergoing orthopaedic surgery, and enflicoxib's long duration makes single‐dose administration attractive. Methods A prospective, multicentre, randomised, masked trial compared enflicoxib (8 mg/kg) given 24 hours before surgery with firocoxib (5 mg/kg) given daily for 7 days. Two hundred
Marta Salichs, José I. Redondo, Anabel Blasco‐Moreno, Llorenç Badiella, Josep Homedes   +4 more
wiley   +1 more source

Methadone Related Poisoning on the Rise in Tehran, Iran [PDF]

Asia Pacific Journal of Medical Toxicology, 2014
Background: In Iran, methadone has been used for methadone maintenance treatment (MMT) as well as analgesic treatment in pain clinics. Recently, there are some reports regarding accidental and intentional methadone poisonings and deaths.
Kambiz Soltaninejad, Hossein Hassanian-Moghaddam, Shahin Shadnia   +2 more
doaj  

The relative risk of fatal poisoning by methadone or buprenorphine within the wider population of England and Wales

BMJ Open, 2015
Objective To examine the population-wide overdose risk emerging from the prescription of methadone and buprenorphine for opioid substitution treatment in England and Wales.Design Retrospective administrative data study.Setting National databases for ...
Dave Marteau, Rebecca McDonald, Kamlesh Patel   +2 more
doaj   +1 more source

Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform

The Milbank Quarterly, EarlyView.
Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD, LAURA DWYER‐LINDGREN, CHRISTOPHER J.L. MURRAY   +2 more
wiley   +1 more source

Retrospective analysis of low-dose methadone and QTc prolongation in chronic pain patients [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundMethadone is a synthetic opioid that is widely used for the treatment of chronic pain. The association between methadone treatment and QT interval prolongation or which can lead to torsades de pointes has been confirmed with larger studies on ...
Billy Huh, Chan-Hong Park
doaj   +1 more source

First Occurrence of Fatal Intoxication Involving Methiodone (IC-26) in Finland; a Medicolegal Autopsy Case Report. [PDF]

Drug Test Anal
ABSTRACT Methiodone (IC‐26) is a non‐fentanyl novel synthetic opioid which has recently been detected in drug seizures in Europe. There is still limited data about the drug in published toxicological case work, both in non‐fatal and fatal cases. We present a medicolegal autopsy case report on a fatal intoxication in an individual undergoing opioid ...
Pakanen L, Ketola RA, Kriikku P.
europepmc   +2 more sources

Methadone’s Moment [PDF]

JAMA
This work discusses unfettering methadone from outdated regulations to empower patients to access treatment and advocate for methadone's expansion in their local communities by working with pharmacies and local health systems.
Incze, Michael A, Simon, Caty, Suen, Leslie W   +2 more
openaire   +3 more sources

Differences in Risk Factors for Severe Preeclampsia and HELLP Syndrome in Singleton Versus Twin Pregnancies: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine whether the associations between pre‐pregnancy risk factors and severe preeclampsia/eclampsia (SPE) and/or HELLP syndrome differ between singleton and twin pregnancies. Design A population‐based retrospective cohort study. Setting British Columbia (BC), Canada.
Mackenzie Campbell, Johanna Koegl, Jeffrey N. Bone, Sofia Nicolls, Janet Lyons, Chantal Mayer, Kenneth I Lim, Julie Van Schalkwyk, K. S. Joseph, Sarka Lisonkova, the ORQA group, A. Christoffersen‐Deb, S. Derikvand, S. John, L. Richter, M. Rougerie, Y. Sabr, M. Vidler   +17 more
wiley   +1 more source