Results 51 to 60 of about 51,765 (292)
Methadone Maintenance Treatment and Cognitive Function: A Systematic Review [PDF]
Methadone has been used as a pharmacotherapy for the treatment of opiate dependence since the mid-1960s. Many studies examining the benefits of methadone maintenance treatment (MMT) for opiate dependence have documented a significant reduction in both ...
Russell, Bruce R. +2 more
core +1 more source
A Novel Use of the “3-Day Rule”: Post-discharge Methadone Dosing in the Emergency Department
Introduction: Methadone is a medically necessary and lifesaving medication for many patients with opioid use disorder. To adequately address these patients’ needs, methadone should be offered in the hospital, but barriers exist that limit its ...
Jenna K. Nikolaides +4 more
doaj +1 more source
This work discusses unfettering methadone from outdated regulations to empower patients to access treatment and advocate for methadone's expansion in their local communities by working with pharmacies and local health systems.
Incze, Michael A +2 more
openaire +3 more sources
Detection of Methadone, LAAM, and Their Metabolites by Methadone Immunoassays [PDF]
l-Alpha-acetylmethadol (LAAM) was recently approved as a substitute for methadone. LAAM, methadone, and their common metabolite, methadol, are extensively N-demethylated. The structural similarities of LAAM and its metabolites to methadone suggest that they may cross-react in methadone immunoassays.
M L, Cheever +2 more
openaire +2 more sources
Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara +1 more
wiley +1 more source
Image7_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG [PDF]
Acute lymphoblastic leukemia (ALL) is a hematologic cancer that mostly affects children. It accounts for over a quarter of ALL pediatric cancers, causing most of the cancer death among children.
Ki-Young Lee (185268) +2 more
core +1 more source
Effect of Eight Weeks Forced Swimming Training with Methadone Supplementation on Aspartate Aminotransferase, Alanine Aminotransferase, and Alkaline Phosphatase of Rats [PDF]
Background & Objective: Narcotics abuse can induce liver disorders; nevertheless, exercises improve liver disorders. The present research aimed to review the effect of eight weeks forced swimming training with methadone supplementation on liver enzymes ...
Seyed Ali Hoseini +5 more
doaj +2 more sources
Objective To examine the population-wide overdose risk emerging from the prescription of methadone and buprenorphine for opioid substitution treatment in England and Wales.Design Retrospective administrative data study.Setting National databases for ...
Dave Marteau +2 more
doaj +1 more source
Methadone is a synthetic opioid used as an analgesic and for the treatment of opioid abuse disorder. The analgesic dose in the pediatric population is not well‐defined.
Blessed W. Aruldhas +8 more
doaj +1 more source
A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu +7 more
wiley +1 more source

