Results 41 to 50 of about 89,531 (280)

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Confidence in providing methadone maintenance treatment of primary care providers in Vietnam

Addiction Science & Clinical Practice
Background Delivering methadone treatment in community health facilities by primary care providers is a task-shifting strategy to expand access to drug use treatment, especially in rural mountainous areas.
Bich Diep Nguyen, Li Li, Chunqing Lin, Thu Trang Nguyen, Steven Shoptaw, Minh Giang Le   +5 more
doaj   +1 more source

Commentary on Gibson et al. (2017): Gestational age and the severity of neonatal abstinence syndrome [PDF]

, 2017
No abstract ...
Allocco, Bier, Desai, Dryden, Gibson, Hodgson, Jones, Kocherlakota, Liu, Mactier, Maeda, McGlone, McGlone, Noormohammadi, Steinhorn, Yuan   +15 more
core   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

The effects of mindfulness‐based interventions on emotion regulation/dysregulation in people with mental health conditions: A systematic review and meta‐analysis

JCPP Advances, EarlyView.
Abstract Background We conducted a systematic review and meta‐analysis to examine the effects of mindfulness‐based interventions (MBIs) on emotion regulation (ER) and emotion dysregulation (ED) in people with any mental health condition. Methods Following a pre‐registered protocol (PROSPERO CRD42024618605), we searched multiple databases (Web of ...
Thomas Easdale‐Cheele, George Nash, Veronika Filobokova, Chloe Westbury, Alessio Bellato   +4 more
wiley   +1 more source

Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

Molecular Pain, 2016
Background Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts ...
Seira Doi BS, Tomohisa Mori PhD, Naoki Uzawa MS, Takamichi Arima BA, Tomoyuki Takahashi BA, Masashi Uchida BS, Ayaka Yawata BA, Michiko Narita BS, Yasuhito Uezono PhD, Tsutomu Suzuki PhD, Minoru Narita PhD   +10 more
doaj   +1 more source

Perceived barriers to methadone maintenance treatment among Iranian opioid users

International Journal for Equity in Health, 2018
Background Opioid use is a severe problem in Iran. Despite methadone maintenance treatment (MMT) programs being one of the most important treatment strategies for reducing individual and public harms associated with opioid use, a large proportion of ...
Maryam Khazaee-Pool, Maryam Moeeni, Koen Ponnet, Arezoo Fallahi, Leila Jahangiri, Tahereh Pashaei   +5 more
doaj   +1 more source

Things We Do for No Reason™: Withholding opioids among patients with acute pain and opioid use disorder

Journal of Hospital Medicine, EarlyView.
Abstract Hospitalists care for patients with acute pain who have an opioid use disorder and require pain management. Hospitalists may withhold opioids for acute pain due to a variety of reasons. However, adequate pain management in patients with opioid use disorder, including with opioids, is the standard of care. This piece explains how to best manage
Anna‐Maria South, Susan L. Calcaterra, Marlene Martin   +2 more
wiley   +1 more source

Intraoperative Methadone Versus Non-Methadone Analgesia in Pediatric Cardiac Surgery: A Retrospective Cohort Study

Children
Introduction: Methadone is an opioid-sparing opioid and it is increasingly used in children undergoing surgery due to its beneficial effects on postoperative pain scores, decreased opioid requirements, and fewer adverse effects compared to other opioids.
Brian Blasiole, Danielle R. Lavage, Hsing-Hua Sylvia Lin, Scott E. Licata, Sahana Sivam, Inesh Sivam, Laura M. Le, Senthilkumar Sadhasivam   +7 more
doaj   +1 more source

Liver transplant and hepatitis C in methadone maintenance therapy: a case report

Substance Abuse Treatment, Prevention, and Policy, 2007
Methadone maintenance therapy for the treatment of opioid dependence continues to carry a social stigma. Until recently, patients on methadone were not considered for liver transplantation.
Bourgeois James A, Craemer Elana, Lester Laura, Ransibrahmanakul Kanat, Prosser Colette C, Hancock Meredith M, Rossaro Lorenzo   +6 more
doaj   +1 more source