ABSTRACT Study Objective To characterize opioid and nonopioid drug use in the week following emergency department (ED)‐initiated extended‐release buprenorphine (XR‐BUP) treatment using both self‐reported data and urine drug screens (UDS). Methods This study uses data collected during a nonrandomized clinical trial of patients with untreated opioid use ...
Ethan Cowan +10 more
wiley +1 more source
A Cohort Comparison of Buprenorphine versus Methadone Treatment for Neonatal Abstinence Syndrome.
E. Hall +6 more
semanticscholar +1 more source
Acceptability of and Implementation Supports for Video Directly Observed Treatment to Enhance Methadone Dosing Flexibility in a Multisite Opioid Treatment Program: Qualitative Rapid Needs Assessment Study. [PDF]
Tsui JI +10 more
europepmc +1 more source
Using multiple recruitment modalities for studies of individuals with alcohol use disorder can expand the phenotypic and genetic heterogeneity of a sample, potentially making it more representative. Abstract Background Alcohol use disorder (AUD) is a common substance use disorder associated with a range of sociodemographic, behavioral, and genetic ...
Alexis C. Edwards +9 more
wiley +1 more source
Christopher M. Jones +4 more
semanticscholar +1 more source
Psilocybin and Ibogaine in Cocaine‐Seeking: Extinction Enhancement Without Relapse Prevention
Using a preclinical model of cocaine self‐administration, we examined the effects of psilocybin and ibogaine on extinction learning and relapse‐like behaviour. Both compounds, administered during the extinction phase, reduced cocaine seeking, indicating facilitation of extinction learning. However, neither treatment prevented cue‐induced reinstatement.
Isis Rita Anzel Koutrouli +16 more
wiley +1 more source
"With this you're not chained down to something": contrasting experiences of opioid agonist treatment and safer supply program participation among people receiving prescribed safer supply. [PDF]
Michaud L +7 more
europepmc +1 more source
Managing the Complex Intersection Between Substance Use Disorders and Infectious Diseases
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 3, March 2026.
Karissa Chow +4 more
wiley +1 more source
The Buprenorphine Paradox: How Buprenorphine Triggers and Resolves Opioid Withdrawal
Buprenorphine can either precipitate or relieve opioid withdrawal depending on the timing of administration relative to full opioid agonist exposure. The article proposes that buprenorphine promotes mu‐opioid receptor (MOR) externalization and resensitization, creating a temporary signaling gap that explains precipitated withdrawal when full agonists ...
Mehdi Haghdoost +6 more
wiley +1 more source
Feasibility and Preliminary Efficacy of Empowered Relief in Patients With Chronic Pain Taking Methadone or Buprenorphine: Single-Arm National Pilot Study. [PDF]
You D +8 more
europepmc +1 more source

