Results 51 to 60 of about 118,303 (321)

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Methadone in Primary Care - One Small Step for Congress, One Giant Leap for Addiction Treatment.

New England Journal of Medicine, 2018
Methadone in Primary Care Methadone clinics serve the needs of some patients well, but for others, the need to obtain medication daily at one fixed site can be too burdensome.
J. Samet, M. Botticelli, M. Bharel
semanticscholar   +1 more source

An evaluation of a methadone treatment programme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University [PDF]

, 1987
The evaluation of a methadone treatment programme was the main focus of this study. A posttest-only design, with a nonequivalent comparison group was used to evaluate both summative and formative aspects of the programme.
Clark, Jahna
core  

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources

Evaluation of Therapeutic Opioids in Skin‐Derived Matrices (Sweat and Sebum) of Neonatal and Pediatric Patients and Their Role in Opioid Incorporation Into Hair

Drug Testing and Analysis, EarlyView.
Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke, Florian Zapf, Julia T. Scherer, Clarissa D. Voegel, Tanja Restin, Marc W. Schmid, Thomas Kraemer, Tina M. Binz   +7 more
wiley   +1 more source

Comparison of Safety and Efficacy of Methadone vs Morphine for Treatment of Neonatal Abstinence Syndrome: A Randomized Clinical Trial

JAMA pediatrics, 2018
Importance Although opioids are used to treat neonatal abstinence syndrome (NAS), the best pharmacologic treatment has not been established. Objective To compare the safety and efficacy of methadone and morphine in NAS.
J. Davis, Jeffrey Shenberger, N. Terrin, J. Breeze, M. Hudak, E. Wachman, P. Marro, Erica L. Oliveira, K. Harvey-Wilkes, Adam Czynski, Barbara Engelhardt, K. D’Apolito, D. Bogen, B. Lester   +13 more
semanticscholar   +1 more source

Client Acceptability for Integrating Antiretroviral Therapy in Methadone Maintenance Therapy Clinics in Sichuan, China. [PDF]

, 2017
BackgroundUsing methadone maintenance therapy (MMT) clinics to deliver antiretroviral therapy (ART) has proven to be effective for promoting treatment initiation and adherence in drug users living with HIV.ObjectivesThe objective of this study was to ...
Cao, Xiaobin, Li, Li, Lin, Chunqing
core   +1 more source

Confidence in providing methadone maintenance treatment of primary care providers in Vietnam

Addiction Science & Clinical Practice
Background Delivering methadone treatment in community health facilities by primary care providers is a task-shifting strategy to expand access to drug use treatment, especially in rural mountainous areas.
Bich Diep Nguyen, Li Li, Chunqing Lin, Thu Trang Nguyen, Steven Shoptaw, Minh Giang Le   +5 more
doaj   +1 more source

Bromazolam Tablet Quantification and Analysis of Post‐Mortem Cases From the National Programme on Substance Use Mortality (NPSUM)

Drug Testing and Analysis, EarlyView.
Tablets submitted to drug checking services that were found to contain bromazolam. Over half of these counterfeit tablets mimicked the appearance of licensed formulations (e.g., alprazolam Xanax bars and diazepam Roche 10 mg pills). Bromazolam is now the most commonly detected street benzodiazepine in drug poisoning deaths in the United Kingdom ...
Matthew Gardner, Molly F. Millea, Sam Craft, Rachael Andrews, Jennifer Scott, Stephen M. Husbands, Christopher R. Pudney, Oliver B. Sutcliffe, Caroline S. Copeland, Peter Sunderland   +9 more
wiley   +1 more source