Results 51 to 60 of about 102,331 (342)

Pharmacokinetic modeling of R and S‐Methadone and their metabolites to study the effects of various covariates in post‐operative children

CPT: Pharmacometrics & Systems Pharmacology, 2021
Methadone is a synthetic opioid used as an analgesic and for the treatment of opioid abuse disorder. The analgesic dose in the pediatric population is not well‐defined.
Blessed W. Aruldhas, Sara K. Quinney, Brian R. Overholser, Michael A. Heathman, Andrea R. Masters, Reynold C. Ly, Hongyu Gao, Senthil Packiasabapathy, Senthilkumar Sadhasivam   +8 more
doaj   +1 more source

Preparation and Administration of a Controlled-Release Delivery System of Chitosan Hydrogel loaded with Methadone and Piroxicam in Experimental Defect of Tibial in Rats; Histopathological Evaluation

Frontiers in Biomedical Technologies, 2023
Purpose: In this study, a controlled release drug delivery system loaded with piroxicam and methadone was synthesized and used subcutaneously in rat with experimental tibial defect and healing were assessed histopathologically. Materials and Methods:
Pegah Khosravian, Moosa Javdani, Melika Masoudi, Abdolnaser Mohebi, Amin Bigham Sadegh, Abolfazl Barzegar   +5 more
doaj   +1 more source

A Systematic Review of Substance Misuse Treatment Processes and Outcomes as Implemented in Prisons for Men in the UK

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background With a rising prison population, a substantial portion of whom are identified as substance misusers, it is important to understand the availability of treatment pathways, their successes and areas for improvement. Given the likely importance of national factors in criminal justice and substance use service provision, we chose to ...
Kim Barnett, Noor Butt, Rosie Allen, Pauline Goodlad, Anne Krayer, Adam O'Neill, Peter Huxley, Catherine Robinson, Emily Peckham, Rob Poole   +9 more
wiley   +1 more source

Perceived barriers to methadone maintenance treatment among Iranian opioid users

International Journal for Equity in Health, 2018
Background Opioid use is a severe problem in Iran. Despite methadone maintenance treatment (MMT) programs being one of the most important treatment strategies for reducing individual and public harms associated with opioid use, a large proportion of ...
Maryam Khazaee-Pool, Maryam Moeeni, Koen Ponnet, Arezoo Fallahi, Leila Jahangiri, Tahereh Pashaei   +5 more
doaj   +1 more source

Commentary on Gibson et al. (2017): Gestational age and the severity of neonatal abstinence syndrome [PDF]

, 2017
No abstract ...
Allocco, Bier, Desai, Dryden, Gibson, Hodgson, Jones, Kocherlakota, Liu, Mactier, Maeda, McGlone, McGlone, Noormohammadi, Steinhorn, Yuan   +15 more
core   +1 more source

Use of methadone

Western Journal of Medicine, 2000
Opiate dependence is a major public health problem associated with the transmission of deadly diseases (human immunodeficiency virus [HIV], hepatitis), criminal activity, accidental overdose, hospital admissions, and death. The treatment of opiate dependence is controversial, and in most patients, a lifelong duration is probably required.1 Methadone is
Thomas E. Kearney, Ilene B. Anderson
openaire   +4 more sources

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients

Drug Testing and Analysis, EarlyView.
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke, Florian Zapf, Tanja Restin, Thomas Kraemer, Tina M. Binz   +4 more
wiley   +1 more source

Effects of integrated programs for substance‐involved mothers on infant and child development outcomes: A systematic review and meta‐analysis

Infant Mental Health Journal: Infancy and Early Childhood, EarlyView.
Abstract Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent‐infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes.
Sophie Barriault, Mary Motz, Lamia Firasta, Hannah McDowell, Patrick R. Labelle, Nancy Poole, Nicole Racine   +6 more
wiley   +1 more source

A Study to Validate a Self-Reported Version of the ONS Drug Dependence Questionnaire [PDF]

, 2011
Aim: A prospective study to establish the reliability of a self-completion version of the Office for National Statistics (ONS) questionnaire for assessing drug dependence of substance misuse clients.
Christo G., Darke S., Gossop M., Jehanli A., Lundy A., Luty J., M. Uddin, Marsden J., McLellan A. T., Poole W. K., R. Holland, Rosen C. S., Schwartz R. H., Sherman M. F., Simpson D. D., Singleton N., V. Maskrey, Vivancos R.   +17 more
core   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source