Results 51 to 60 of about 49,525 (269)
Retrospective analysis of low-dose methadone and QTc prolongation in chronic pain patients [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundMethadone is a synthetic opioid that is widely used for the treatment of chronic pain. The association between methadone treatment and QT interval prolongation or which can lead to torsades de pointes has been confirmed with larger studies on ...
Billy Huh, Chan-Hong Park
doaj +1 more source
Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024
ELECTROPHORESIS, EarlyView.ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley +1 more source
Journal of Substance Abuse Treatment, 1991 We describe a patient on methadone maintenance who developed distal leg edema after years of treatment. The edema resolved when methadone was discontinued and recurred when it was restarted. This patient is compared to three others reported in the literature who also developed fluid retention shortly after being placed on methadone.
Hong-Shion Yeh +4 more
openaire +3 more sources
Detection of Methadone, LAAM, and Their Metabolites by Methadone Immunoassays [PDF]
Journal of Analytical Toxicology, 1999 l-Alpha-acetylmethadol (LAAM) was recently approved as a substitute for methadone. LAAM, methadone, and their common metabolite, methadol, are extensively N-demethylated. The structural similarities of LAAM and its metabolites to methadone suggest that they may cross-react in methadone immunoassays.
Matthew L. Cheever +2 more
openaire +3 more sources
Infant Mental Health Journal: Infancy and Early Childhood, EarlyView.Abstract Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent‐infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes.
Sophie Barriault +6 more
wiley +1 more source
Heart ViewsMethadone is considered relatively safe when compared to other opioids. Methadone, however, can cause respiratory depression and QT prolongation. Among patients on methadone maintenance therapy, the rate of cannabis use is high.
Muhammad Adnan Zaman +2 more
doaj +1 more source
Frontiers in Genetics, 2018 Objective: To explore the association between methadone dosage, plasma drug concentration, SNPs of μ-opioid receptor gene (OPRM1), ATP-binding cassette subfamily B member 1 gene (ABCB1), and methadone maintenance treatment (MMT) response.Method: A total ...
Sufang Peng +8 more
doaj +1 more source
Landscape of informed consent practices and challenges in point‐of‐care clinical trials
Learning Health Systems, EarlyView.Abstract Point‐of‐care trials, an approach to trial design that assesses medical product effectiveness while fully integrating research and care, represent a promising opportunity to generate practically relevant evidence efficiently for priority disease areas.
Caleigh Propes +2 more
wiley +1 more source
Methadone switching for refractory cancer pain
BMC Palliative Care, 2022 Background Methadone is commonly considered an alternative opioid treatment for refractory cancer pain. This study aims to investigate the efficacy, safety, and cost of methadone in the treatment of refractory cancer pain.
Haiying Ding +8 more
doaj +1 more source
Learning Health Systems, EarlyView.Abstract Introduction Substance use disorders (SUDs) continue to place heavy burdens on patients, health systems, and communities. Rapidly evolving treatment for SUDs requires health systems that can efficiently and effectively assess data and integrate evidence to practice.
Emily Bacon +8 more
wiley +1 more source