Results 1 to 10 of about 7,283,036 (268)
Genetic variants in NECTIN4 encoding an adhesion molecule are associated with continued opioid use.
PLoS ONE, 2020 Methadone is a synthetic opioid used as maintenance treatment for patients addicted to heroin. Skin irritation is one of the adverse events caused by opioid use.
Chiu-Ping Fang +9 more
doaj +1 more source
Gender disparities in opioid treatment progress in methadone versus counseling
Substance Abuse Treatment, Prevention, and Policy, 2021 Background In the United States, the high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities calls for understanding factors that contribute to making progress in treatment.
Erick Guerrero +4 more
doaj +1 more source
Research on Addiction, 2011 Objective: the aim of the present study was the survey of methadone maintenance treatment on health psyche and having hope in drug addicted persons. Method: the sample population was 60, 30 people were under Methadone Maintenance Treatment and 30 people ...
Aazam Shahmoradi +2 more
doaj
Temperamental Characteristics and Problem-Solving Skills among Patients on Opioid Agonists [PDF]
Addiction and Health, 2018 Background: The study of temperament and problem-solving styles in people with substance abuse is important in promoting the functions of prevention and treatment of this social problem.
Shahin Eslami-Saaraab +3 more
doaj
Methadone as a “Tumor Theralgesic” against Cancer
Frontiers in Pharmacology, 2017 Methadone has beneficial characteristics as an analgesic against cancer pain, including high bioavailability, multiple receptor affinities, and lack of active metabolites that might induce adverse side effects.
Marta Michalska +2 more
doaj +1 more source
A Novel Use of the “3-Day Rule”: Post-discharge Methadone Dosing in the Emergency Department
Western Journal of Emergency MedicineIntroduction: Methadone is a medically necessary and lifesaving medication for many patients with opioid use disorder. To adequately address these patients’ needs, methadone should be offered in the hospital, but barriers exist that limit its ...
Jenna K. Nikolaides +4 more
doaj +1 more source
BMJ Open, 2019 Introduction More than 2 million individuals in the USA have an opioid use disorder (OUD). Methadone maintenance treatment is the gold standard of medication-based treatment for OUD, but high-dose methadone is associated with cardiotoxicity and ...
Annabelle M Belcher +15 more
doaj +1 more source
Methadone Initiation in the Emergency Department for Opioid Use Disorder
Western Journal of Emergency MedicineIntroduction: Overdose deaths from high-potency synthetic opioids, including fentanyl and its analogs, continue to rise along with emergency department (ED) visits for complications of opioid use disorder (OUD).
Daniel Wolfson +12 more
doaj +1 more source
Efficacy of D,L-methadone in the treatment of glioblastoma in vitro
CNS Oncology, 2018 Aim: Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM). Methods: We analyzed the μ-opioid receptor expression in a set of GBM cell lines and investigated the efficacy of D,L-methadone alone and in combination with ...
Konstantin Brawanski +9 more
doaj +1 more source
Comparison of Behavioral Brain Systems and Craving between Individuals Undergoing Methadone and Buprenorphine Maintenance Treatment [PDF]
Research on AddictionObjective: The present study aimed to compare the behavioral brain systems and craving between individuals undergoing maintenance treatment with Methadone and Buprenorphine. Method: In this causal-comparative research, the statistical population included
Mohammadreza Salmani Kalan +3 more
doaj