“It’s so much easier for them to just come to us”: a qualitative study examining the implementation of mobile methadone treatment serving a residential SUD treatment program [PDF]
Addiction Science & Clinical PracticeBackground Methadone is a highly effective treatment for opioid use disorder (OUD). Yet its impact is constrained by low rates of treatment initiation and retention, driven in part by geographic inequalities in the availability of methadone-providing ...
David Frank +8 more
doaj +2 more sources
Cardiac Assessment of Individuals with Opioid Use Disorder under Methadone Treatment [PDF]
Journal of Research in Pharmacy PracticeObjective: Methadone treatment is effective for managing opioid use disorder (OUD) but raises concerns about its impact on cardiac function. This study aimed to assess the prevalence of cardiac dysfunction among individuals under methadone treatment ...
Hoda Barkhordari +4 more
doaj +2 more sources
Trait impulsivity prospectively predicts lower methadone treatment retention: moderation by pain catastrophizing [PDF]
Addiction Science & Clinical PracticeBackground Empirical evidence supports the use of methadone as the standard of care for opioid use disorder. However, low retention in methadone treatment is one of the largest impediments to treatment success.
Annabelle M. Belcher +9 more
doaj +2 more sources
Potential improvement in spatial accessibility of methadone treatment with integration into other outpatient substance use disorder treatment programs, New York City, 2024. [PDF]
PLoS ONEBackgroundMethadone is an effective treatment for opioid use disorder; however, its provision in the US is limited to federally-regulated opioid treatment programs (OTP).
Marcus A Bachhuber +2 more
doaj +2 more sources
Methadone treatment and its dangers [PDF]
Medicina, 2009 Methadone is a long-acting synthetic opioid with high affinity for various opioid receptors, especially for μ-opioid receptors. Methadone has been used as a successful pharmacologic intervention for the treatment of heroin dependence and acute and chronic pain.
Reingardienė, Dagmara +2 more
core +4 more sources
Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?. [PDF]
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
core +9 more sources
The role of concomitant drugs in the aetiology of fatal heroin- and methadone- related overdose [PDF]
, 2008 Heroin and methadone poisoning are significant causes of death of young people in the United Kingdom. In a high proportion of these fatalities concomitant substances are also detected.
Oliver, Phillip
core +6 more sources
Maternal methadone use in pregnancy : factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources [PDF]
, 2009 The objectives of this study were to investigate factors associated with the development of neonatal abstinence syndrome (NAS) and to assess the implications for healthcare resources of infants born to drug-misusing women. Design.
Hepburn, M. +3 more
core +4 more sources
Methadone maintenance treatment [PDF]
BMJ, 1995 EDITOR,—Our review of methadone maintenance treatment1 elicited a range of views.2 Wolfgang Poser and colleagues correctly comment that methadone treatment protects against death due to an overdose of opiates2—an effect that we have reviewed elsewhere.3 The problem of deaths due to overdoses of diverted methadone, however, is considerable in Britain ...
Mattick, Richard +6 more
openaire +3 more sources
The Pan African Medical Journal, 2021 Methadone maintenance treatment is reported as cost-effective in treatment of opioid use disorder. Estimated cost of providing methadone varies widely in different regions but there is no data regarding cost of methadone treatment in Kenya.
Brenda Mogaka1 +3 more
doaj +1 more source