Results 81 to 90 of about 7,283,036 (268)

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam   +7 more
wiley   +1 more source

Prescribed alternative stimulants among people who use unregulated stimulants: Examining the association between maximum dose reached and medication discontinuation in the first 3 years of implementation in British Columbia, Canada

open access: yesAddiction, EarlyView.
Abstract Background and aims In 2020, British Columbia (BC), Canada, introduced ‘Prescribed Alternatives’ (PA) as an approach to offering regulated substances to people accessing the unregulated supply. This study aimed to estimate and compare prescribing characteristics of dextroamphetamine and methylphenidate stimulant PAs in BC, to estimate ...
Bin Zhao   +11 more
wiley   +1 more source

Joint associations of recovery capital and polygenic risk with electronic health record observed remission and relapse in substance use disorder: Longitudinal evidence from the All of Us research program

open access: yesAddiction, EarlyView.
Abstract Background and aims Recovery capital and genetic liability may be related to substance use disorder (SUD) remission through psychosocial and biologic pathways, but their joint association with remission course remains poorly understood. This question is clinically important because people entering remission differ in recovery resources and ...
Janaka V. Kosgolla, Douglas C. Smith
wiley   +1 more source

Accidental overdose admissions and premature death: A large population‐based data‐linkage cohort study in New South Wales, Australia (PAVLOVA 4)

open access: yesAddiction, EarlyView.
Abstract Background and aims People with substance use disorders have reduced life‐expectancy; however, risks of premature death from injuries and natural causes following an accidental overdose are not well characterised. This study aimed to estimate risk of premature death (by cause and over time), and disease burden following hospitalised accidental
Firouzeh Noghrehchi   +5 more
wiley   +1 more source

Methylenedioxymethamphetamine (MDMA)‐related fatal poisoning in Australia, 2016 to 2025: Trends, characteristics and toxicology

open access: yesAddiction, EarlyView.
Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke   +5 more
wiley   +1 more source

A Case Report of Neuroleptic Malignant Syndrome during Methadone Therapy

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022
Background and Objective: Methadone is an opioid agonist used for the treatment of addiction to opioid drugs. Toxic leukoencephalopathy can cause serious problem and even be life-threatening.
MJ Nasr   +3 more
doaj  

The association between chronic pain and non‐fatal overdose in people who inject drugs: Longitudinal cohort study in Montreal, Canada, 2017 to 2025

open access: yesAddiction, EarlyView.
Abstract Background and aims The prevalence of chronic pain is elevated among people who inject drugs. Chronic pain may motivate drug use, potentially increasing the risk of non‐fatal overdose. We aimed to estimate the association between chronic pain and non‐fatal overdose in people who inject drugs.
Sarah Larney   +9 more
wiley   +1 more source

An Investigation of the Effectiveness of Cognitive Behavioral Therapy and Methadone Treatment on Quality of Life, Cravings Management, and Psychological Distress in Individuals Abstaining from Drugs

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2017
Aim and Background: Substance use disorder (SUD) is one of main issues in the field of mental health and can have negative consequences for patients as well as their families and the society in which they live.
امیرتورج پورنژدی   +2 more
doaj  

Chronic pain treatment experiences and barriers among opioid agonist treatment participants who inject drugs: A qualitative study

open access: yesAddiction, EarlyView.
Abstract Background and aim Co‐occurring chronic pain affects nearly half of people receiving opioid use disorder (OUD) treatment. Although this pain is often severe, it is usually inadequately managed. Stigma and clinical complexity associated with OUD are thought to further restrict access to pain care.
Jie Yang   +6 more
wiley   +1 more source

The Mediating Role of COVID-19-related Stress in the Relationship between Rumination and Aggression in Patients under Methadone Maintenance Therapy [PDF]

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
Introduction: The stress caused by COVID-19 had affected many people in society, especially individuals at risk. The present study was carried out to investigate, firstly, whether COVID-19-related stress plays a mediating role in the relationship between
Mohammad Douzandeh Nargesi   +2 more
doaj  

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