Results 21 to 30 of about 94,112 (278)

Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]

open access: yes, 2008
Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins   +47 more
core   +1 more source

Plasma inflammatory factors are associated with anxiety, depression, and cognitive problems in adults with and without methamphetamine dependence: An exploratory protein array study

open access: yesFrontiers in Psychiatry, 2015
Objectives: It is hypothesized that immune factors influence addictive behaviors and contribute to relapse. The primary study objectives were to: 1) compare neuropsychiatric symptoms across adults with active methamphetamine dependence, in early ...
Marilyn eHuckans   +10 more
doaj   +1 more source

Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats

open access: yesFrontiers in Psychiatry, 2020
Heroin and methamphetamine are both popular illicit drugs in China. Previous clinical data showed that habitual users of either heroin or methamphetamine abuse the other drug for substitution in case of unavailability of their preferred drug. The present
Di-sen Mei   +9 more
doaj   +1 more source

Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. [PDF]

open access: yes, 2015
Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
Dean, AC   +5 more
core   +4 more sources

Executive Control and Striatal Resting-State Network Interact with Risk Factors to Influence Treatment Outcomes in Alcohol-Use Disorder

open access: yesFrontiers in Psychiatry, 2017
Alterations within mesocorticolimbic terminal regions commonly occur with alcohol use disorder (AUD). As pathological drug-seeking behavior may arise as a consequence of alcohol-induced neuroadaptations, it is critical to understand how such changes ...
Milky Kohno   +13 more
doaj   +1 more source

Effects of Dopamine- and Serotonin-Related Compounds on Methamphetamine-Induced Self-Injurious Behavior in Mice

open access: yesJournal of Pharmacological Sciences, 2004
Methamphetamine induces hyperlocomotion, and high doses of methamphetamine induce self-injurious behavior (SIB) in rodents. It is well known that the monoaminergic system is involved in methamphetamine-induced behavior.
Tomohisa Mori   +3 more
doaj   +1 more source

N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users. [PDF]

open access: yes, 2018
Background:Methamphetamine induces neuronal N-acetyl-aspartate synthesis in preclinical studies. In a preliminary human proton magnetic resonance spectroscopic imaging investigation, we also observed that N-acetyl-aspartate+N-acetyl-aspartyl-glutamate in
Alger, Jeffry R   +5 more
core   +2 more sources

Methamphetamine-induced encephalopathy in the absence of hyperammonemia

open access: yesBMC Psychiatry, 2023
Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany   +4 more
doaj   +1 more source

Prenatal Exposure to Methamphetamine Causes Vascular Dysfunction in Adult Male Rat Offspring

open access: yesFrontiers in Cardiovascular Medicine, 2022
Methamphetamine use during pregnancy can have negative consequences on the offspring. However, most studies investigating the impact of prenatal exposure to methamphetamine have focused on behavioral and neurological outcomes.
Hasitha Chavva   +5 more
doaj   +1 more source

Treatment utilization and barriers to treatment: Results of a survey of dependent methamphetamine users

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2011
Background Australia has one of the highest rates of methamphetamine use in the world; however, treatment access for methamphetamine is comparatively low.
Lee Nicole K   +3 more
doaj   +1 more source

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