Results 31 to 40 of about 5,691 (138)

Application of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VI.

open access: yesPLoS ONE, 2013
DNA topoisomerases are highly exploited targets for antimicrobial drugs. The spread of antibiotic resistance represents a significant threat to public health and necessitates the discovery of inhibitors that target topoisomerases in novel ways.
James A Taylor   +4 more
doaj   +1 more source

Engineering Rhodosporidium toruloides for limonene production

open access: yesBiotechnology for Biofuels, 2021
Background Limonene is a widely used monoterpene in the production of food, pharmaceuticals, biofuels, etc. The objective of this work was to engineer Rhodosporidium toruloides as a cell factory for the production of limonene.
Sasa Liu   +7 more
doaj   +1 more source

Application of Biochar on methane production through organic solid waste and ammonia inhibition

open access: yesEnvironmental Challenges, 2021
The present study discusses the role of biochar in enhancing methane (biogas) production from organic solid waste (OSW) employing a co-culture of Pseudomonas aeruginosa and Methanosarcina mazei.
Apourv Pant, J.P.N. Rai
doaj   +1 more source

The Methanosarcina barkeri genome: comparative analysis withMethanosarcina acetivorans and Methanosarcina mazei reveals extensiverearrangement within methanosarcinal genomes [PDF]

open access: yes, 2006
We report here a comparative analysis of the genome sequence of Methanosarcina barkeri with those of Methanosarcina acetivorans and Methanosarcina mazei. All three genomes share a conserved double origin of replication and many gene clusters. M.
Han, Cliff S.   +11 more
core   +1 more source

Biomethane production from sugar beet pulp under cocultivation with Clostridium cellulovorans and methanogens

open access: yesAMB Express, 2019
This study was demonstrated with a coculture fermentation system using sugar beet pulp (SBP) as a carbon source combining the cellulose-degrading bacterium Clostridium cellulovorans with microbial flora of methane production (MFMP) for the direct ...
Hisao Tomita   +2 more
doaj   +1 more source

Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas

open access: yeseLife, 2020
Key to CRISPR-Cas adaptive immunity is maintaining an ongoing record of invading nucleic acids, a process carried out by the Cas1-Cas2 complex that integrates short segments of foreign genetic material (spacers) into the CRISPR locus.
Alison B Hickman   +4 more
doaj   +1 more source

Untersuchungen zur Regulation der Transkription bei Methanosarcina mazei [PDF]

open access: yes, 2004
To investigate the Methanosarcina mazei regulation of transcription, an in vitro transcription system with purified Methanococcus thermolithotrophicus RNA polymerase and recombinant TBP and TFB from Methanosarcina mazei was established.
Thomsen, Jens
core   +1 more source

Methanosarcina mazei G�1 Proteomic Response to Methylotrophic Substrates [PDF]

open access: yes, 2019
Transcriptomics is often touted to be the silver bullet to determining the protein levels within a microorganism when comparing such proteins under two or more different biological conditions.
Jarrett, Deborah
core   +1 more source

Nonsense and sense suppression abilities of original and derivative Methanosarcina mazei pyrrolysyl-tRNA synthetase-tRNA(Pyl) pairs in the Escherichia coli BL21(DE3) cell strain. [PDF]

open access: yesPLoS ONE, 2013
Systematic studies of nonsense and sense suppression of the original and three derivative Methanosarcina mazei PylRS-tRNA(Pyl) pairs and cross recognition between nonsense codons and various tRNA(Pyl) anticodons in the Escherichia coli BL21(DE3) cell ...
Keturah A Odoi   +3 more
doaj   +1 more source

Biofilm formation of mucosa-associated methanoarchaeal strains

open access: yesFrontiers in Microbiology, 2014
Although in nature most microorganisms are known to occur predominantly in consortia or biofilms, data on archaeal biofilm formation are in general scarce.
Corinna eBang   +8 more
doaj   +1 more source

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