Results 51 to 60 of about 5,691 (138)

A Novel Polyphosphate‐Degrading Enzyme Confers Growth on Exogenous Polyphosphate in the Archaeon Haloferax volcanii

Environmental Microbiology, Volume 28, Issue 7, July 2026.
A novel polyP‐degrading enzyme with an activity differing from those currently known was found in Haloferax volcanii, conferring the ability for this microbe to grow on extracellular polyP. These findings further our understanding of the potential ecological roles of polyP and how archaea metabolise this essential biopolymer.
Jack W. F. Nicholls, Vincent O'Flaherty, Timothy M. Lenton, John W. McGrath, Jason P. Chin   +4 more
wiley   +1 more source

Mechanismen der Protonentranslokation in Methanosarcina mazei Gö1

, 2001
Die Umsetzung von Methanol und Wasserstoff plus Kohlendioxid im Zuge der Methanogenese ist an den Aufbau eines elektrochemischen Ionenpotentials über die Cytoplasmamembran gekoppelt.
Bäumer, Sebastian Andreas
core   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, Volume 293, Issue 11, Page 3303-3319, June 2026.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Genomic and Transcriptomic Insights Into the Autotrophic Metabolism on H2 + CO2 or CO of the Thermophilic Acetogenic Model Organism Moorella thermoacetica

Environmental Microbiology, Volume 28, Issue 4, April 2026.
Moorella thermoacetica is the model organism for elucidation of acetogenesis. The reduction of CO2 to acetate is well studied, but how redox carrier balancing and energy conservation are maintained during autotrophic growth and how H2 is oxidised remains enigmatic.
Florian P. Rosenbaum, Anja Poehlein, Rolf Daniel, Volker Müller   +3 more
wiley   +1 more source

Structural insight into substrate and product binding in an archaeal mevalonate kinase.

PLoS ONE, 2018
Mevalonate kinase (MK) is a key enzyme of the mevalonate pathway, which produces the biosynthetic precursors for steroids, including cholesterol, and isoprenoids, the largest class of natural products.
Bradley R Miller, Yan Kung
doaj   +1 more source

Structural basis for the site-specific incorporation of lysine derivatives into proteins. [PDF]

PLoS ONE, 2014
Posttranslational modifications (PTMs) of proteins determine their structure-function relationships, interaction partners, as well as their fate in the cell and are crucial for many cellular key processes.
Veronika Flügel, Milan Vrabel, Sabine Schneider   +2 more
doaj   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Genetic Encoding of a Trifunctional Photo‐Cross‐Linker with a Cleavable Alkyl Ester Moiety

ChemBioChem, Volume 27, Issue 3, 12 February 2026.
A novel noncanonical amino acid, DiZAAsu, possessing photo‐cross‐linking, biotinylation, and alkaline‐cleavable functionalities, is genetically encoded by an engineered pyrrolyl‐tRNA synthetase mutant. The alkyl ester moiety expands the design space of cleavable photo‐cross‐linkable amino acids.
Masahiro Takayama, Tomoya Tsubota, Takao Yamaguchi, Kosuke Chiba, Takumi Yoshida, Yoshiyuki Hari, Yu‐Shi Tian, Daisuke Takaya, Asuka Mori, Tomohito Tsukamoto, Kenji Ishimoto, Yukio Ago, Yoshiaki Okada, Kensaku Sakamoto, Takefumi Doi, Kaori Fukuzawa, Satoshi Obika, Shinsaku Nakagawa, Nobumasa Hino   +18 more
wiley   +1 more source

Functional and structural characterization of the Methanosarcina mazei proteasome and PAN complexes.

, 2006
We have cloned the proteasome and the proteasome activating nucleotidase (PAN) genes from the mesophilic archaeon Methanosarcina mazei and produced the respective proteins in Escherichia coli cultures.
Martinez-Arias, R, Medalia, Ohad, Medalia, N, Medalia, O, Martinez-Arias, Rosa, Sharon, Michal, Medalia, O., Zwickl, P., Sharon, M, Medalia, N., Zwickl, P, Robinson, C. V., Medalia, Noa, Zwickl, Peter, Mihalache, O, Robinson, CV, Robinson, Carol V., Sharon, M., Mihalache, Oana, Martinez-Arias, R., Mihalache, O.   +20 more
core   +1 more source

The Potential Role of Two Red Macroalgae (Asparagopsis taxiformis and A. armata) That Promote Anti‐Methanogenic Activities in Laboratory Conditions

Animal Science Journal, Volume 97, Issue 1, January/December 2026.
ABSTRACT The objectives of this study were to evaluate the effects of two red macroalgae species (RMS; Asparagopsis taxiformis and A. armata) on rumen fermentation profiles, greenhouse gas (GHG) emissions, microbiome changes, and anti‐methanogenic activities.
Byeng R. Min, Giuseppa Genovese, Damiano Spagnuolo, Mariline Hilaire, Hossam Ismael, Santosh Chaudhary, Dipti W. Pitta, Nagaraju Indugu   +7 more
wiley   +1 more source