Results 51 to 60 of about 13,680 (210)

A Case of IgG4‐Related Disease Developing During Long‐Term High‐Dose Intravenous Epoprostenol Therapy in a Patient With Idiopathic Pulmonary Arterial Hypertension

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Long‐term intravenous (IV) epoprostenol is a key therapy for pulmonary arterial hypertension (PAH); however, rare immune‐mediated conditions occurring during therapy remain incompletely characterised. We report a 34‐year‐old man with idiopathic PAH who developed low‐grade fever and bilateral pulmonary infiltrates after 11 years of IV ...
Takashi Inao   +9 more
wiley   +1 more source

Pharmacotherapy of hyperthyroidism in cats (ro.) [PDF]

open access: yesMedicamentul Veterinar, 2013
Currently, the feline hyperthyroidism possesses three types of treatment that includes medication, surgery and radioactive therapie. The success of these therapies consists in obtaining favorable results, by inhibiting thyroid hormone secretion, reducing
Andreea Pap, Romeo T. Cristina
doaj  

Pre-treatment Neutropenia in Children and Adolescents with Autoimmune Hyperthyroidism

open access: yesJCRPE, 2021
Objective:Neutropenia can occur in untreated autoimmune hyperthyroidism (AIH) or in association with treatment with the anti-thyroid drug, methimazole (MMI).
Melissa Kaori S. Litao   +2 more
doaj   +1 more source

New cases of δ‐aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro   +22 more
wiley   +1 more source

Experimental modeling of hypothyroidism: principles, methods, several advanced research directions in cardiology

open access: yesRussian Open Medical Journal, 2021
Hypothyroidism is one of the most common pathological conditions in modern clinical practice. Due to the fact that the targets of thyroid hormones are virtually all organs and tissues, the morphological and clinical manifestations arising with a ...
Aleksey M. Chaulin   +3 more
doaj   +1 more source

Early Low‐Dose Rituximab for Mild‐to‐Moderate Thyroid Eye Disease: A Preliminary Evaluation of Efficacy and Safety

open access: yesInternational Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Background Thyroid eye disease (TED) is an autoimmune inflammatory condition linked to thyroid dysfunction, which can result in disfigurement and potential vision loss. Recently, immunomodulatory therapies such as rituximab have demonstrated potential benefit in managing TED.
Ming Lu   +3 more
wiley   +1 more source

Hyperthyroidism in cats, part II : scintigraphic diagnosis and radioiodine treatment [PDF]

open access: yes, 2016
In the second part of this review article, the diagnostic aspects of thyroid scintigraphy are discussed, with major emphasis on hyperthyroidism, followed by an overview of radioiodine ...
Daminet, Sylvie   +4 more
core   +1 more source

Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats - Induction of phenol UDP-glucuronyltransferase by methimazole [PDF]

open access: yes, 1995
Glucuronidation of iodothyronines in rat liver is catalyzed by at least three UDP-glucuronyltransferases (UGTs): bilirubin UGT, phenol UGT, and androsterone UGT.
Bonthuis, F. (Fred)   +6 more
core   +2 more sources

Methimazole-Related Substances: Structural Characterization and In Silico Toxicity Assessment

open access: yesCrystals
The continuous tightening of pharmaceutical regulations forces drug manufacturers to unambiguously characterize the substances related to the active pharmaceutical ingredients (API). Here, we report the synthesis, complete spectroscopic, chromatographic,
Leo Štefan   +4 more
doaj   +1 more source

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

open access: yesGlia, Volume 73, Issue 12, Page 2407-2426, December 2025.
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf   +3 more
wiley   +1 more source

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