Results 141 to 150 of about 531,866 (340)

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

open access: yesAdvanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao   +8 more
wiley   +1 more source

Systems genetics identifies methionine as a high risk factor for Alzheimer's disease

open access: yesFrontiers in Neuroscience
As a dietary strategy, methionine restriction has been reported to promote longevity and regulate metabolic disorders. However, the role and possible regulatory mechanisms underlying methionine in neurodegenerative diseases such as Alzheimer's disease ...
Congmin Wang   +10 more
doaj   +1 more source

Workshop and desk study to appraise technical difficulties associated with organic pullet rearing [PDF]

open access: yes, 2001
Background To date, Regulation (EC) 1804/1999 and UKROFS Standards allow conventionally reared pullets up to 18 weeks of age to be brought into systems of organic egg production. Pullets must be reared according to the rules laid down in Regulation (EC)
Gordon, S
core  

Response of Broilers to DL-Methionine Hydroxy Analog Free Acid, DL-Methionine, and L-Methionine

open access: yesPoultry Science, 1985
An experiment was designed to compare graded levels of DL-methionine hydroxy analog, free acid, 88% in aqueous solution; 2-hydroxy-4-(methylthio)butanoic acid (HMB), the aqueous solution of the sodium salt of DL-methionine (40%) (DLM), and crystalline L-methionine (LM) as sources of supplemental methionine activity.
openaire   +2 more sources

Principles for Rigorous Design and Application of Synthetic Microbial Communities

open access: yesAdvanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang   +21 more
wiley   +1 more source

Effects of L-Methionine and DL-Methionine on Growth Performance, Methionine-Metabolizing Enzyme Activities, Feather Traits, and Intestinal Morphology of Medium-Growing, Yellow-Feathered Chickens between 1 and 30 Days of Age

open access: yesAnimals
This experiment investigated the effects of L-Methionine (L-Met) on growth performance, Met-metabolizing enzyme activity, feather traits, and small intestinal morphological characteristics, and compared these with DL-Methionine (DL-Met) for medium ...
Xiajing Lin   +9 more
doaj   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló   +2 more
wiley   +1 more source

Reactions of proteins with oxidizing lipids: 2. Influence on protein quality and on the bioavailability of lysine, methionine, cyst(e)ine and tryptophan as measured in rat assays [PDF]

open access: yes, 2017
1. The consequences of reactions between protein and oxidizing lipids on the nutritional quality of food proteins have been investigated using a whey protein-methyl linolenate-water model system. 2.
Finot, P. A.   +2 more
core  

Usefulness of L-[Methyl-<sup>11</sup>C]Methionine Positron Emission Tomography in the Treatment of Idiopathic Hypertrophic Cranial Pachymeningitis

open access: gold, 2012
Keisuke Miyake   +7 more
openalex   +2 more sources

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