Results 141 to 150 of about 122,610 (155)

A GRAVIMETRIC METHOD FOR THE DETERMINATION OF METHIONINE

open access: hybrid, 1942
Eliot F. Beach, D. Maxwell Teague
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Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Science, 2016
Tumors put in a vulnerable position Cancer cells often display alterations in metabolism that help fuel their growth. Such metabolic “rewiring” may also work against the cancer cells, however, by creating new vulnerabilities that can be exploited ...
Konstantinos J. Mavrakis   +43 more
semanticscholar   +1 more source

l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.

The Journal of the Science of Food and Agriculture, 2019
BACKGROUND Methionine is an essential sulfur-containing amino acid. To elucidate the influence of l-methionine on activation of the nuclear factor erythroid 2-related factor 2-antioxidant responsive element (Nrf2-ARE) antioxidant pathway to stimulate the
Zhengxuan Wang   +6 more
semanticscholar   +1 more source

Systematic Analysis of Bottlenecks in a Multibranched and Multilevel Regulated Pathway: The Molecular Fundamentals of l-Methionine Biosynthesis in Escherichia coli.

ACS Synthetic Biology, 2018
To produce chemicals and fuels from renewable resources, various strategies and genetic tools have been developed to redesign pathways and optimize the metabolic flux in microorganisms.
Jian-Feng Huang   +7 more
semanticscholar   +1 more source

Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.

Molecular Nutrition & Food Research, 2017
SCOPE Serine lies at the central node linking biosynthetic flux from glycolysis to glutathione synthesis and one-carbon metabolic cycle which are closely related to antioxidant capacity.
Xihong Zhou   +5 more
semanticscholar   +1 more source

CO2 Hydrate Formation Promoted by a Natural Amino Acid l-Methionine for Possible Application to CO2 Capture and Storage

, 2017
We first demonstrated that L-methionine, a natural amino acid, can be used to dramatically enhance CO2 uptake kinetics in the formation of CO2 hydrate without the use of energy-intensive mixing technologies or environmentally harmful chemicals.
Cai Yuanhao   +6 more
semanticscholar   +1 more source

Metabolic engineering of Escherichia coli for microbial production of L‐methionine

Biotechnology and Bioengineering, 2017
L‐methionine has attracted a great deal of attention for its nutritional, pharmaceutical, and clinical applications. In this study, Escherichia coli W3110 was engineered via deletion of a negative transcriptional regulator MetJ and over‐expression of ...
Jian-Feng Huang   +6 more
semanticscholar   +1 more source

From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span

Annals of the New York Academy of Sciences, 2016
Methionine restriction is a widely reported intervention for increasing life span in several model organisms. Low circulating levels of methionine are evident in the long‐lived naked mole‐rat, suggesting that it naturally presents with a life‐extending ...
R. McIsaac   +3 more
semanticscholar   +1 more source

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