Results 191 to 200 of about 10,041 (230)
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Immunoreactive Methionine-Enkephalin Secretion by Porcine Uterus*
Endocrinology, 1991The current study examined the presence of immunoreactive methionine-enkephalin (ir-MENK) in porcine uterine fluid and endometrial extracts, characterized ir-MENK biochemically, and investigated the effect of ovarian steroids on uterine secretion of ir-MENK. Porcine uterine fluid was collected by flushing the uterine lumen with saline.
W I, Li, L C, Sung, F W, Bazer
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Methionine Enkephalin: A New Cytokine—Human Studies
Clinical Immunology and Immunopathology, 1997The effects of methionine enkephalin (met-enkephalin) on human immune function are reviewed. This pentapeptide functions to upregulate, or enhance, immune function in the majority of donor samples at low doses and suppresses at high doses. The influence of this molecule is shared by the central nervous, neuroendocrine, and immune systems.
N P, Plotnikoff +4 more
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Immunocytochemical localization of methionine enkephalin: Preliminary observations
Life Sciences, 1977Abstract Antiserum directed against methionine enkephalin (metenkephalin) was used to determine its anatomical distribution in rat brain. Cross reactivity of that antiserum was not detectable against leucine enkephalin (leu-enkephalin), β-lipotropin (β-LPH), β-endorphin or assorted peptide fragments of met-enkephalin; alpha-endorphin was 370 times ...
S J, Watson +3 more
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Methionine enkephalin regulates microglia polarization and function
International Immunopharmacology, 2016Methionine enkephalin (MENK), an opioid peptide, is known to function as a regulator in the immune system. As microglia are considered the most important immune cells in the central nervous system (CNS), we aimed to assess the function of MENK on microglia polarization and tumoricidal responses.
Xuxu, Xu +6 more
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Alcoholism: Clinical and Experimental Research, 2004
Abstract: Background: Opiate peptides are involved in the physical dependence on ethanol. Levels of methionine enkephalin (MEnk), for example, are affected by ethanol. No study on the effect of ethanol on endomorphin, the endogenous ligand for the μ‐opiate receptor, has yet been conducted.Methods: We examined the effect of ethanol ingestion on serum
William A, Banks +2 more
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Abstract: Background: Opiate peptides are involved in the physical dependence on ethanol. Levels of methionine enkephalin (MEnk), for example, are affected by ethanol. No study on the effect of ethanol on endomorphin, the endogenous ligand for the μ‐opiate receptor, has yet been conducted.Methods: We examined the effect of ethanol ingestion on serum
William A, Banks +2 more
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Phencyclidine decreases methionine-enkephalin content in rat striatum
Neuroscience Letters, 1983The acute administration of phencyclidine induced a decrease in methionine-enkephalin levels in rat striatum, as measured by specific radioimmunoassay. The maximum decrease (about 40% with respect to controls) was obtained at a dose of 20 mg/kg, 30 min after intraperitoneal injection.
FRATTA, WALTER, ZIVKOVIC B, GESSA G.
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International journal of peptide and protein research, 1980
Biological activities are reported for two different types of analogues of methionine enkephalin. Cyclic analogues, bridged between the amino- and carboxy- terminals of the parent peptide, are inactive. In contrast, significant levels of activity are displayed by linear isosterically modified analogues in which the Tyr1-Gly2 peptide bond is replaced by
D, Hudson, R, Sharpe, M, Szelke
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Biological activities are reported for two different types of analogues of methionine enkephalin. Cyclic analogues, bridged between the amino- and carboxy- terminals of the parent peptide, are inactive. In contrast, significant levels of activity are displayed by linear isosterically modified analogues in which the Tyr1-Gly2 peptide bond is replaced by
D, Hudson, R, Sharpe, M, Szelke
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Eine vereinfachte Synthese von Methionin‐Enkephalin
Journal für Praktische Chemie, 1978A Convenient Synthesis of Methionin‐EnkephalinAn efficient synthesis of methionin‐enkephalin has been developed by prolongation of the C‐terminal amino acid methylester using Boc‐Phe‐OHNomenklatur und Abkürzungen nach den Regeln der IUPAC‐IUB‐Commission on Bichemical Nomenclature: Hoppe‐Seyler's Z. physiol. Chem. 348, 256 (1967), J. Biol. Chem.
Günter Losse, Klaus‐Dieter Wehrstedt
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Effect of methionine-enkephalin on xanthophore aggregation
Peptides, 1980The intracranial injection of an opioid antagonist (naloxone) caused aggregation of xanthophores in goldfish scales. This aggregating effect produced by naloxone was inhibited by an injection of methionine-enkephalin (M-ENK). M-ENK, when injected together with melatonin which normally produces aggregation of xanthophores, interfered with the effect of ...
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Methionine enkephalin metabolism by murine macrophage ectopeptidase(s)
Regulatory Peptides, 1994Ectopeptidases which hydrolyze opioid and other neuropeptides have been identified in brain, kidney and intestine. In this study, identification of the enzymes metabolizing the opioid peptide methionine enkephalin (YGGFM) in murine macrophages was undertaken.
B C, Miller +3 more
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