Results 101 to 110 of about 180,383 (183)

Mitochondrial MsrB2 serves as a switch and transducer for mitophagy

EMBO Molecular Medicine, 2019
Mitophagy can selectively remove damaged toxic mitochondria, protecting a cell from apoptosis. The molecular spatial–temporal mechanisms governing autophagosomal selection of reactive oxygen species (ROS)‐damaged mitochondria, particularly in a platelet (
Seung Hee Lee, Suho Lee, Jing Du, Kanika Jain, Min Ding, Anis J Kadado, Gourg Atteya, Zainab Jaji, Tarun Tyagi, Won‐ho Kim, Raimund I Herzog, Amar Patel, Costin N Ionescu, Kathleen A Martin, John Hwa   +14 more
doaj   +1 more source

Physiological Function of Cyanobacterial Methionine Sulfoxide Reductase [PDF]

, 2015
Methionine is a sulfur-containing amino acid which is susceptible to oxidation by Reactive Oxygen Species (ROS). Oxidation of methionine could lead to protein denaturation; with methionine itself turning into methionine sulfoxide (MetSO), a radical which
Uy, Jhonne Anderson
core   +1 more source

Preparation of a library of methionine sulfoxide reductase for applications in synthesis of chiral sulfoxides [PDF]

, 2018
Chiral sulfoxides are important compounds in the pharmaceutical and chemical industries, however, their enantioselective synthesis providing only one desired enantiomer is not fully mastered.
Havelka, Václav
core  

Significance of Four Methionine Sulfoxide Reductases in Staphylococcus aureus

PLOS ONE, 2015
Staphylococcus aureus is a major human pathogen and emergence of antibiotic resistance in clinical staphylococcal isolates raises concerns about our ability to control these infections. Cell wall-active antibiotics cause elevated synthesis of methionine sulfoxide reductases (Msrs: MsrA1 and MsrB) in S. aureus. MsrA and MsrB enzymes reduce S-epimers and
Singh, Vineet K., Vaish, Manisha, Johansson, Trintje R., Baum, Kyle R., Ring, Robert P., Singh, Saumya, Shukla, Sanjay K., Moskovitz, Jackob   +7 more
openaire   +5 more sources

Periplasmic methionine sulfoxide reductase (MsrP)-a secondary factor in stress survival and virulence of Salmonella Typhimurium. [PDF]

FEMS Microbiol Lett, 2023
Chandra HB, Shome A, Sahoo R, Apoorva S, Bhure SK, Mahawar M.   +5 more
europepmc   +1 more source

Reduction of DABS-L-methionine-dl-sulfoxide by protein methionine sulfoxide reductase from polymorphonuclear leukocytes: stereospecificity towards the l-sulfoxide

, 1994
A new synthetic substrate for protein methionine sulfoxide reductase is proposed. We show that extracts from human polymorphonuclear leukocytes can reduce 4-dimethylaminoazobenzene-4'-sulfonyl-L-methionine-dl-sulfoxide [DABS-L-Met-dl-(O)] to the ...
BROVELLI, AUGUSTA, MINETTI, GIAMPAOLO, BALDUINI, CESARE   +2 more
core  

Sexually dimorphic effects of methionine sulfoxide reductase A (MsrA) on murine longevity and health span during methionine restriction. [PDF]

Geroscience, 2023
Thyne KM, Salmon AB.
europepmc   +1 more source

Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA) [PDF]

, 1999
Oxidation of methionine residues in proteins to methionine sulfoxide can be reversed by the enzyme peptide methionine sulfoxide reductase (MsrA, EC 1.8.4.6). We cloned the gene encoding a human homologue (hMsrA) of the enzyme, which has an 88% amino acid
Alfred Hansel, Hoshi, Toshinori, Roland Schönherr, Stefan H. Heinemann, Herbert Weissbach, Toshinori Hoshi, Weissbach, Herbert, Nathan Brot, Kuschel, Lioba, Hansel, Alfred, Heinemann, Stefan H., Lioba Kuschel, Brot, Nathan, Schönherr, Roland   +13 more
core   +1 more source

Focus on Molecules: Methionine sulfoxide reductase A [PDF]

Experimental Eye Research, 2012
Marc, Kantorow, Wanda, Lee, Daniel, Chauss   +2 more
openaire   +2 more sources

Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides. [PDF]

ACS Catal, 2023
Anselmi S, Carvalho ATP, Serrano-Sanchez A, Ortega-Roldan JL, Caswell J, Omar I, Perez-Ortiz G, Barry SM, Moody TS, Castagnolo D.   +9 more
europepmc   +1 more source