Results 1 to 10 of about 3,923,906 (342)

Investigation of aflatoxins occurrence in flavoring preparations for the alcoholic beverage industry

Frontiers in Food Science and Technology, 2023
An exploratory study was carried out to determine the occurrence of aflatoxins B1, B2, G1, and G2 in different aromatic preparations used in the production of bitters, liqueurs and flavored wines.
Bruna Laratta, Serena Carpentieri, Domenico Cautela   +2 more
doaj   +1 more source

Determination of a novel anticonvulsant drug GIZh-290 in rat plasma by liquid chromatography–tandem mass spectrometry

Фармакокинетика и Фармакодинамика, 2022
GIZh-290 is a new derivative of 4-phenylpyrrolidone, based on the structures of racetams that combine anticonvulsant and nootropic effects. The method of high-performance liquid chromatography with mass spectrometric detection was developed and validated
P. O. Bochkov, I. P. Khrustova, A. A. Litvin, G. B. Kolyvanov, R. V. Shevchenko, V. P. Zherdev   +5 more
doaj   +1 more source

Quantification of a potential anticonvulsant drug GIZh-298 in rat plasma by liquid chromatography-mass spectrometry

Фармакокинетика и Фармакодинамика, 2022
GIZh-298 is a new derivative of 4-phenylpyrrolidone with anticonvulsant and nootropic effects. A selective and sensitive HPLC-MS technique for the quantitative determination of GIZh-298 in rat blood plasma has been developed and validated.
P. O. Bochkov, O. Yu. Kravtsova, G. B. Kolyvanov, A. A. Litvin, S. S. Boyko, V. P. Zherdev   +5 more
doaj   +1 more source

Validation of a Screening Method Based on a Needle Stochastic Sensor for the Determination of Interleukins 1β, 6, and 12 in Biological Samples

Proceedings, 2020
Interleukins proved to be valuable biomarkers for different diseases. Interleukins 1β, 6, and 12 can be used as biomarkers for brain cancer diagnosis, and therefore this paper proposed a needle stochastic sensor based on protoporphyrin IX immobilized in ...
Sorin Sebastian Gheorghe, Ruxandra Maria Ilie-Mihai, Raluca-Ioana Stefan-van Staden, Alexandru Bratei   +3 more
doaj   +1 more source

Method development, validation, and impurity measurement of β-estradiol from radiolabeled [131I]β-estradiol using radio-high-performance liquid chromatography for radioligand of saturation binding assay

Journal of Advanced Pharmaceutical Technology & Research, 2023
β-estradiol is an estrogen steroid hormone and acts as an estrogen receptor agonist. Radiolabeled β-estradiol is widely used as a radioligand for binding assays. In this present study, the synthesis of [131I]β-estradiol has been successfully carried out.
Isti Daruwati, Abednego Kristande Gwiharto, Hendris Wongso, Tri Hanggono Achmad, Mukh Syaifudin, Muchtaridi Muchtaridi   +5 more
doaj   +1 more source

Simultaneous determination of Guaifenesin, codeine phosphate, phenylephrine hydrochloride, and sodium benzoate in syrup pharmaceutical form by RP-HPLC

Al-Kitab Journal for Pure Sciences, 2023
This work describes the development of the RP-HPLC method for the simultaneous estimation of Guaifenesin, codeine phosphate, phenylephrine, and sodium benzoate.
Muthana S. Ali, Ali E. Karim, Maiser Z. Mohye, Azza M. Al-metwali, Salah N. Ibrahim   +4 more
doaj   +1 more source

Method Validation and Investigation of the Levels of Pharmaceuticals and Personal Care Products in Sludge of Wastewater Treatment Plants and Soils of Irrigated Golf Course

Molecules, 2020
The validation of a sensitive and reliable analytical procedure for the determination of pharmaceutical and personal care products (PPCPs) in solid environmental samples is reported in this study.
Olufemi Temitope Ademoyegun, Omobola Oluranti Okoh, Anthony Ifeanyi Okoh   +2 more
doaj   +1 more source

Circulating choline and phosphocholine measurement by a hydrophilic interaction liquid chromatography–tandem mass spectrometry

Heliyon, 2023
Background: Given the growing interest in studying the role of choline and phosphocholine in the development and progression of tumor pathology, in this study we describe the development and validation of a fast and robust method for the simultaneous ...
Giulia Guerra, Francesco Segrado, Patrizia Pasanisi, Eleonora Bruno, Salvatore Lopez, Francesco Raspagliesi, Michela Bianchi, Elisabetta Venturelli   +7 more
doaj   +1 more source

Two Ways to Achieve the Same Goal—Two Validated Quantitative NMR Strategies for a Low-Abundance Natural Product in Standardized Extracts: The Case of Hepatodamianol in Turnera diffusa

Molecules, 2022
The quantification of low-abundance secondary metabolites in plant extracts is an analytical problem that can be addressed by different analytical platforms, the most common being those based on chromatographic methods coupled to a high-sensitivity ...
Aída Parra-Naranjo, Cecilia Delgado-Montemayor, Ricardo Salazar-Aranda, Rocío Castro-Ríos, Alma L. Saucedo, Noemí Waksman-Minsky   +5 more
doaj   +1 more source

Validação de método para determinação de resíduos de amoxicilina aplicado à validação de limpeza em indústria farmacêutica de penicilânicos Validation of a method for determination of amoxicillin residues applied to cleaning validation process in penicillins pharmaceutical industry

Química Nova, 2010
The aim of this work was the single-laboratory validation of a quantitative method for the determination of amoxicillin residues in support of cleaning control and validation.
Maria Luiza Pinheiro Costa Gomes, Scheilla Vitorino Carvalho de Souza   +1 more
doaj   +1 more source