Results 21 to 30 of about 13,804,522 (255)

Development of HPLC Method for Quantification of Sinigrin from Raphanus sativus Roots and Evaluation of Its Anticancer Potential

Molecules, 2020
Sinigrin, a precursor of allyl isothiocyanate, present in the Raphanus sativus exhibits diverse biological activities, and has an immense role against cancer proliferation.
Anroop B. Nair, Dipal Gandhi, Snehal S. Patel, Mohamed A. Morsy, Bapi Gorain, Mahesh Attimarad, Jigar N. Shah   +6 more
doaj   +1 more source

Detection of Nitrated, Oxygenated and Hydrogenated Polycyclic Aromatic Compounds in Smoked Fish and Meat Products

Foods, 2022
Polycyclic aromatic hydrocarbons (PAHs) are present in smoked food products. More toxic nitrated (NPAH) and oxygenated (OPAH) PAHs derivatives are found concomitantly to PAHs and are therefore believed to be found in smoked food products. However, only a
Elisa Sonego, Bina Bhattarai, Lene Duedahl-Olesen   +2 more
doaj   +1 more source

Development and Validation of a Bioanalytical Method for 3′- and 6′-Sialyllactose in Minipig Liver and Kidney Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to Analysis of Tissue Distribution

Molecules, 2020
Breast milk contains human milk oligosaccharides (HMOs), including sialyllactose (SL). SL is composed of sialic acid and lactose, and is divided into 3′-SL and 6′-SL according to the binding position.
Han Young Eom, Seok-In Jang, Jong-Hwa Lee   +2 more
doaj   +1 more source

Authenticity Analysis of Cold-Pressed Orange Essential Oils by GC/MS on Polymethoxyflavone Components

Agriculture, 2023
Citrus essential oil combines numerous components with many qualities and control issues. For example, how to monitor volatile components and nonvolatile substances simultaneously is a major problem.
Kai-Min Yang, Chih-Wei Chen, Min-Hung Chen, Hsin-Chun Chen, Li-Yun Lin   +4 more
doaj   +1 more source

Natural Occurrence of Alternaria Toxins in Agricultural Products and Processed Foods Marketed in South Korea by LC–MS/MS

Toxins, 2022
Alternaria mycotoxins including alternariol (AOH), alternariol monomethyl ether (AME), altenuene (ALT), altertoxin-I (ATX-I), tentoxin (TEN), and tenuazonic acid (TeA), are ubiquitous contaminants in agricultural products.
So Young Woo, Sang Yoo Lee, Tae Kyun Jeong, Su Mi Park, Joong Hyuck Auh, Han-Seung Shin, Hyang Sook Chun   +6 more
doaj   +1 more source

Method Development, Validation and Stability Study of Diltiazem by RP-HPLC Method

Journal of Pharmaceutical Research
Background: The main goal of this experiment was to create and test a reliable and fast HPLC method for measuring the amount of Diltiazem, a drug that lowers blood pressure, in large quantities and to conduct stability studies.
Henerita Dash, Sudhir Kumar Sahoo
doaj   +1 more source

Procrustes Cross-Validation — a Bridge Between Cross-Validation and Independent Validation Set [PDF]

, 2020
In this paper we propose a new approach for validation of chemometric models. It is based on k-fold cross-validation algorithm, but, in contrast to conventional cross-validation, our approach makes possible to create a new dataset, which carries sampling
Sergei, Zhilin, Oxana Ye., Rodionova, Alexey L., Pomerantsev, Sergey, Kucheryavskiy   +3 more
core   +1 more source

Validation of a one-step reverse transcription PCR detection method for Tobamovirus maculatessellati, in tomato (Solanum lycopersicum L.) and pepper (Capsicum annuum L.)

Frontiers in Plant Science
The solanaceous-infecting tobamoviruses are closely related and hence it can be challenging to detect them using serological or molecular methods, particularly when present in a mixed infection.
Chellappan Padmanabhan, Andrea Gilliard, Kai-Shu Ling, Yazmín Rivera   +3 more
doaj   +1 more source

Research on detection methods of related substances and degradation products of the antitumor drug selpercatinib

Frontiers in Chemistry
BackgroundSelpercatinib, a selective RET kinase inhibitor, is approved for treating various cancers with RET gene mutations such as RET-rearranged thyroid cancer and non-small cell lung cancer.
Jingjing Xiang, Liangliang Cai, Qin Wang, Yonghong Zhu, Yong Han   +4 more
doaj   +1 more source

Complete intra-laboratory validation of a LAL assay for bacterial endotoxin determination in EBV-specific cytotoxic T lymphocytes

Molecular Therapy: Methods & Clinical Development, 2021
Endotoxin content is a critical factor that affects the safety of biological pharmaceutical products. International pharmacopoeias describe several reference methods to determine endotoxin levels in advanced therapy medicinal product (ATMP) preparations.
Salvatore Pasqua, Maria Concetta Niotta, Giuseppina Di Martino, Davide Sottile, Bruno Douradinha, Monica Miele, Francesca Timoneri, Mariangela Di Bella, Nicola Cuscino, Chiara Di Bartolo, Pier Giulio Conaldi, Danilo D’Apolito   +11 more
doaj   +1 more source