Results 21 to 30 of about 1,892,546 (315)

A Validated RP-HPLC Method for the Simultaneous Detection and Quantification of Pyridoxine and Terizidone in Pharmaceutical Formulations

Analytica, 2021
Tuberculosis (TB) remains a life-threatening infection, and it is well-known that effective TB treatment is associated with multiple drugs administered to infected patients on a daily basis.
Ngabo Yves Musafili, Halima Samsodien, Marique Elizabeth Aucamp   +2 more
doaj   +1 more source

Validation of Inactivation Methods for Arenaviruses [PDF]

Viruses, 2021
Several of the human-pathogenic arenaviruses cause hemorrhagic fever and have to be handled under biosafety level 4 conditions, including Lassa virus. Rapid and safe inactivation of specimens containing these viruses is fundamental to enable downstream processing for diagnostics or research under lower biosafety conditions. We established a protocol to
Silke Olschewski, Anke Thielebein, Chris Hoffmann, Olivia Blake, Jonas Müller, Sabrina Bockholt, Elisa Pallasch, Julia Hinzmann, Stephanie Wurr, Neele Neddersen, Toni Rieger, Stephan Günther, Lisa Oestereich   +12 more
openaire   +3 more sources

Increased efficacy for in-house validation of real-time PCR GMO detection methods [PDF]

, 2009
To improve the efficacy of the in-house validation of GMO detection methods (DNA isolation and real-time PCR, polymerase chain reaction), a study was performed to gain insight in the contribution of the different steps of the GMO detection method to the ...
I. M. J. Scholtens, L. Hougs, B. Molenaar, Kok, E.J., Scholtens-Toma, I.M.J., Molenaar, B., Thissen, J.T.N.M., E. J. Kok, Voet, H., van der, Hougs, L., J. T. N. M. Thissen, H. van der Voet, van der Voet, H.   +12 more
core   +1 more source

Imprinted Polymeric Beads-Based Screen-Printed Potentiometric Platforms Modified with Multi-Walled Carbon Nanotubes (MWCNTs) for Selective Recognition of Fluoxetine

Nanomaterials, 2020
Herein, we present a new validated potentiometric method for fluoxetine (FLX) drug monitoring. The method is based on the integration of molecular imprinting polymer (MIP) beads as sensory elements with modified screen-printed solid contact ion-selective
Saad S.M. Hassan, Ayman H. Kamel, Abd El-Galil E. Amr, Heba M. Hashem, E.M. Abdel Bary   +4 more
doaj   +1 more source

Intra-Laboratory Validation of Alpha-Galactosidase Activity Measurement in Dietary Supplements

Molecules, 2021
Introduction: Alpha-galactosidase (α-Gal) is an enzyme responsible for the hydrolyzation of glycolipids and glycoprotein commonly found in dietary sources.
Elena Fabris, Michela Bulfoni, Alessandro Nencioni, Emanuele Nencioni   +3 more
doaj   +1 more source

History and development of validation with the ESP-r simulation program [PDF]

, 2008
It is well recognised that validation of dynamic building simulation programs is a long-term complex task. There have been many large national and international efforts that have led to a well-established validation methodology comprising analytical ...
Macdonald, Iain, Strachan, Paul, Strachan, P. A., Kokogiannakis, Georgios, Kokogiannakis, G., Macdonald, I. A.   +5 more
core   +1 more source

Optimal Selection of Model Validation Experiments : Guided by Coverage [PDF]

, 2021
Modeling and Simulation (M&S) is seen as a means to mitigate the difficulties associated with increased system complexity, integration, and cross-couplings effects encountered during development of aircraft subsystems.
Hällqvist, Robert,, Eek, Magnus,, Braun, Robert,, Krus, Petter,   +3 more
core   +1 more source

Development of HPLC Method for Quantification of Sinigrin from Raphanus sativus Roots and Evaluation of Its Anticancer Potential

Molecules, 2020
Sinigrin, a precursor of allyl isothiocyanate, present in the Raphanus sativus exhibits diverse biological activities, and has an immense role against cancer proliferation.
Anroop B. Nair, Dipal Gandhi, Snehal S. Patel, Mohamed A. Morsy, Bapi Gorain, Mahesh Attimarad, Jigar N. Shah   +6 more
doaj   +1 more source

Detection of Nitrated, Oxygenated and Hydrogenated Polycyclic Aromatic Compounds in Smoked Fish and Meat Products

Foods, 2022
Polycyclic aromatic hydrocarbons (PAHs) are present in smoked food products. More toxic nitrated (NPAH) and oxygenated (OPAH) PAHs derivatives are found concomitantly to PAHs and are therefore believed to be found in smoked food products. However, only a
Elisa Sonego, Bina Bhattarai, Lene Duedahl-Olesen   +2 more
doaj   +1 more source

Development and Validation of a Bioanalytical Method for 3′- and 6′-Sialyllactose in Minipig Liver and Kidney Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to Analysis of Tissue Distribution

Molecules, 2020
Breast milk contains human milk oligosaccharides (HMOs), including sialyllactose (SL). SL is composed of sialic acid and lactose, and is divided into 3′-SL and 6′-SL according to the binding position.
Han Young Eom, Seok-In Jang, Jong-Hwa Lee   +2 more
doaj   +1 more source