Results 31 to 40 of about 3,970,126 (291)

Controlling the Overfitting of Heritability in Genomic Selection through Cross Validation. [PDF]

, 2017
In genomic selection (GS), all the markers across the entire genome are used to conduct marker-assisted selection such that each quantitative trait locus of complex trait is in linkage disequilibrium with at least one marker.
Jia, Zhenyu
core   +2 more sources

Split-domain calibration of an ecosystem model using satellite ocean colour data [PDF]

, 2004
The application of satellite ocean colour data to the calibration of plankton ecosystem models for large geographic domains, over which their ideal parameters cannot be assumed to be invariant, is investigated.
Bleck, Brock, Campbell, Christian, Conkright, Eppley, Evans, Evans, Fasham, Fasham, Fennel, Friedrichs, Friedrichs, Glover, Gregg, Gunson, Hemmings, Hurtt, Hurtt, Jia, John C.P. Hemmings, Kraus, Longhurst, Losa, Matear, McClain, McKay, Meric A. Srokosz, Michael J.R. Fasham, Moyer, Oschlies, Oschlies, Oschlies, Palmer, Peter Challenor, Press, Prunet, Prunet, Rossow, Sarmiento, Sarmiento, Sathyendranath, Schartau, Siegel, Spitz, Spitz   +45 more
core   +1 more source

Independent validation as a validation method for classification

Quantitative and Computational Methods in Behavioral Sciences, 2023
The use of classifiers provides an alternative to conventional statistical methods. This involves using the accuracy with which data is correctly assigned to a given group by the classifier to apply tests to compare the performance of classifiers. The conventional validation methods for determining the accuracy of classifiers have the disadvantage that
Braun, Tina, Eckert, Hannes, Von Oertzen, Timo   +2 more
openaire   +1 more source

Optimisation of pressurized liquid extraction using a multivariate chemometric approach for the determination of anticancer drugs in sludge by ultra high performance liquid chromatography–tandem mass spectrometry [PDF]

, 2013
The present paper describes an analytical method for the determination of 2 widely administered anticancer drugs, ifosfamide and cyclophosphamide, contained in sewage sludge. The method relies on the extraction from the solid matrix by pressurized liquid
Albasi, Claire, Claparols, Catherine, Joannis-Cassan, Claire, Sablayrolles, Caroline, Seira, Jordan, Vignoles-Montrejaud, Mireille   +5 more
core   +4 more sources

Validation of a one-step reverse transcription PCR detection method for Tobamovirus maculatessellati, in tomato (Solanum lycopersicum L.) and pepper (Capsicum annuum L.)

Frontiers in Plant Science
The solanaceous-infecting tobamoviruses are closely related and hence it can be challenging to detect them using serological or molecular methods, particularly when present in a mixed infection.
Chellappan Padmanabhan, Andrea Gilliard, Kai-Shu Ling, Yazmín Rivera   +3 more
doaj   +1 more source

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Bolann BJ, Klee GG, Kushnir MM, Magera M, Rasmussen K   +4 more
core   +1 more source

Research on detection methods of related substances and degradation products of the antitumor drug selpercatinib

Frontiers in Chemistry
BackgroundSelpercatinib, a selective RET kinase inhibitor, is approved for treating various cancers with RET gene mutations such as RET-rearranged thyroid cancer and non-small cell lung cancer.
Jingjing Xiang, Liangliang Cai, Qin Wang, Yonghong Zhu, Yong Han   +4 more
doaj   +1 more source

Complete intra-laboratory validation of a LAL assay for bacterial endotoxin determination in EBV-specific cytotoxic T lymphocytes

Molecular Therapy: Methods & Clinical Development, 2021
Endotoxin content is a critical factor that affects the safety of biological pharmaceutical products. International pharmacopoeias describe several reference methods to determine endotoxin levels in advanced therapy medicinal product (ATMP) preparations.
Salvatore Pasqua, Maria Concetta Niotta, Giuseppina Di Martino, Davide Sottile, Bruno Douradinha, Monica Miele, Francesca Timoneri, Mariangela Di Bella, Nicola Cuscino, Chiara Di Bartolo, Pier Giulio Conaldi, Danilo D’Apolito   +11 more
doaj   +1 more source

A combined sensitivity analysis and kriging surrogate modeling for early validation of health indicators [PDF]

, 2014
To increase the dependability of complex systems, one solution is to assess their state of health continuously through the monitoring of variables sensitive to potential degradation modes. When computed in an operating environment, these variables, known
LAMOUREUX, Benjamin, MASSÉ, Jean-Rémi, MECHBAL, Nazih   +2 more
core   +6 more sources

Development and validation of a PMA-qPCR method for accurate quantification of viable Lacticaseibacillus paracasei in probiotics

Frontiers in Microbiology
The effectiveness of probiotic products hinges on the viability and precise quantification of probiotic strains. This study addresses this crucial requirement by developing and validating a precise propidium monoazide combination with quantitative ...
Lizheng Guo, Xiaolei Ze, Yingxin Jiao, Chengyu Song, Xi Zhao, Zhiquan Song, Shuaicheng Mu, Yiru Liu, Yuanyuan Ge, Yu Jing, Su Yao   +10 more
doaj   +1 more source