Results 121 to 130 of about 1,892,546 (315)
Molecules, 2015 The antioxidant activity and chlorogenic acid and caffeic acid contents were investigated from different parts of Acanthopanax senticosus and A. koreanum.
Young-Hyun Kim +9 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Feature Selective Validation (FSV) Method [PDF]
, 2005 The feature selective validation (FSV) method is one of the candidate techniques for the quantitative validation of computational electromagnetics (CEM), particularly within electromagnetic compatibility (EMC) and signal integrity (SI).
Duffy A +4 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Analytical performance evaluation of the Biosystems BA400 Clinical Chemistry Analyzer
Journal of Associated Medical Sciences, 2015 Introduction: BA400 (Biosystems, Spain) is a new clinical chemistry analyzer for spectrophotometric, tubidimetric and ion-selective determination of biochemical analytes. Validation of method performance before routine operation is needed.
Khanittha Taneyhill +5 more
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Radiometric validation of multi-spectral ocean colour satellite data in high biomass Southern Benguela waters [PDF]
, 2009 Includes bibliographical references (leaves 106-117).This study forms the first step towards a comprehensive ocean colour satellite validation strategy for the Southern Benguela region, and underlines the value of a statistical radiometric validation as ...
Robertson, Elisabeth
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Verification and validation of knowledge-based systems with an example from site selection. [PDF]
In this paper, the verification and validation of Knowledge-Based Systems (KBS) using decision tables (DTs) is one of the central issues. It is illustrated using real-market data taken from industrial site selection problems.One of the main problems of ...
Vanthienen, Jan, Wets, G, Witlox, Frank
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