Results 31 to 40 of about 3,923,906 (342)

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Bolann BJ, Klee GG, Kushnir MM, Magera M, Rasmussen K   +4 more
core   +1 more source

Is Weinberg's Method Valid? [PDF]

Acta geneticae medicae et gemellologiae, 1974
Suppose that L like-sexed and U unlike-sexed twins have been observed. Weinberg's method estimates the numbers of DZ andMZ twins as DZ = 2U and MZ = L—U. This method is based on the assumptions that (1) the sex ratio in DZ twins is 1/2 and (2) the sexes of DZ twins are determined independently and with the same probability in all parents; in ...
openaire   +2 more sources

Validation of a one-step reverse transcription PCR detection method for Tobamovirus maculatessellati, in tomato (Solanum lycopersicum L.) and pepper (Capsicum annuum L.)

Frontiers in Plant Science
The solanaceous-infecting tobamoviruses are closely related and hence it can be challenging to detect them using serological or molecular methods, particularly when present in a mixed infection.
Chellappan Padmanabhan, Andrea Gilliard, Kai-Shu Ling, Yazmín Rivera   +3 more
doaj   +1 more source

Research on detection methods of related substances and degradation products of the antitumor drug selpercatinib

Frontiers in Chemistry
BackgroundSelpercatinib, a selective RET kinase inhibitor, is approved for treating various cancers with RET gene mutations such as RET-rearranged thyroid cancer and non-small cell lung cancer.
Jingjing Xiang, Liangliang Cai, Qin Wang, Yonghong Zhu, Yong Han   +4 more
doaj   +1 more source

Development and validation of a PMA-qPCR method for accurate quantification of viable Lacticaseibacillus paracasei in probiotics

Frontiers in Microbiology
The effectiveness of probiotic products hinges on the viability and precise quantification of probiotic strains. This study addresses this crucial requirement by developing and validating a precise propidium monoazide combination with quantitative ...
Lizheng Guo, Xiaolei Ze, Yingxin Jiao, Chengyu Song, Xi Zhao, Zhiquan Song, Shuaicheng Mu, Yiru Liu, Yuanyuan Ge, Yu Jing, Su Yao   +10 more
doaj   +1 more source

Face Validation Method Alternatives for Shiphandling Fuzzy Logic Difficulty Model [PDF]

, 2014
The development of shiphandling difficulty model for ferry is based on the empirical experience through the Master of Ro-Ro ferries. The SHDMF is consisted from two parts which are the Analytic Hierarchy Process (AHP) and Fuzzy Inference System.
Benabdelhafid, A. (Abdellatif), Priadi, A. A. (Antoni), Tjahjono, T. (Tri)   +2 more
core  

Ridge Fusion in Statistical Learning [PDF]

, 2014
We propose a penalized likelihood method to jointly estimate multiple precision matrices for use in quadratic discriminant analysis and model based clustering.
Geyer, Charles J., Price, Bradley S., Rothman, Adam J.   +2 more
core   +2 more sources

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Fast Cross-Validation via Sequential Testing [PDF]

, 2015
With the increasing size of today's data sets, finding the right parameter configuration in model selection via cross-validation can be an extremely time-consuming task.
Braun, Mikio, Krueger, Tammo, Panknin, Danny   +2 more
core  

Reweighted nuclear norm regularization: A SPARSEVA approach

, 2015
The aim of this paper is to develop a method to estimate high order FIR and ARX models using least squares with re-weighted nuclear norm regularization. Typically, the choice of the tuning parameter in the reweighting scheme is computationally expensive,
Blomberg, Niclas, Ha, Huong, Rojas, Cristian R., Wahlberg, Bo, Welsh, James S.   +4 more
core   +1 more source