Results 101 to 110 of about 1,680,347 (310)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

IEA EBC Annex 57 ‘Evaluation of Embodied Energy and CO_2eq for Building Construction' [PDF]

, 2017
The current regulations to reduce energy consumption and greenhouse gas emissions (GHG) from buildings have focused on operational energy consumption. Thus legislation excludes measurement and reduction of the embodied energy and embodied GHG emissions ...
A. Houlihan Wiberg, A. Moncaster, Anand, ASHRAE, Birgisdottir, Birgisdottir, Birgisdottir, Birgisdottir, Birgisdóttir, Brown, C. Chae, Chae, Crawford, Crishna, Darby, De Castro, Dixit, Dixit, Dixit, Dixit, Dokka, EFKM, EN 15643-2, EN 15804.2012+A1, EN 15978, EPBD, Gavotsis, Georges, H. Birgisdottir, Henson, Houlihan Wiberg, Inman, IPCC, ISO 21929-1, ISO 21930, ISO 21931-10, ISO14025, K. Yokoyama, Knight, Kristjansdottir, Langston, Liljenström, Lützkendorf, Lützkendorf, Lützkendorf, M. Balouktsi, Mistretta, Monahan, Nakao, Oka, Oka, Passer, Passer, Pomponi, Rasmussen, Rauf, S. Seo, Seo, SETAC, SIA, Säynäjoki, T. Lützkendorf, T. Malmqvist, T. Oka, Tarancon, UN, UNEP, Vukotic, Wallhagen, Yokoo, Yokoo, Yokoyama, Železná   +72 more
core   +1 more source

Quality audit typology and methodology

Buhalterinės apskaitos teorija ir praktika, 2014
The methodology of audit is extensively researched both foreign and Lithuanian authors, but there isn’t a full theory of audit, in which is mentioned all the currently existing types of audit. This is due to the quality audit typology and methodology is not fully explored and clearly systematized. Analysing audit concepts it is a challenge to determine
Indrė Pečiulytė, Juozas Ruževičius
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A Systematic Review of Telehealth in Palliative Care: Caregiver Outcomes

, 2016
Objective: Telehealth interventions have proven efficacy in healthcare, but little is known about the results of such interventions in palliative care.
Head, Barbara A., Schapmire, Tara J., Zheng, Yongqiang   +2 more
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Cluster randomised trials in the medical literature: two bibliometric surveys [PDF]

, 2004
Background: Several reviews of published cluster randomised trials have reported that about half did not take clustering into account in the analysis, which was thus incorrect and potentially misleading.
A Donner, A Donner, A Donner, C Emslie, CM Wright, CR Elley, D Nutbeam, DG Altman, DG Altman, DM Murray, E Rink, G Meyer, J Cornfield, J Martin Bland, JCFM Wetsteyn, JM Bland, JM Bland, JM Simpson, MAH Russell, MJ Gardner, MJ Gardner, MK Campbell, P Isaakidis, S Puffer, SM Eldridge, SM Kerry, SM Kerry, SM Kerry, SP Varnell   +28 more
core   +4 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Acupuncture and vitamin B12 injection for Bell′s palsy: no high-quality evidence exists

Neural Regeneration Research, 2015
OBJECTIVE: To assess the efficacy of acupuncture combined with vitamin B 12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell′s palsy.
Li-li Wang, Ling Guan, Peng-liang Hao, Jin-long Du, Meng-xue Zhang   +4 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source