Results 111 to 120 of about 8,171,446 (309)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Quality Improvement Division Annual Report 2016

open access: yes, 2017
This report provides a high level overview of work completed by the Quality Improvement Division (QID) in 2016. In 2016 QID focused on developing and articulating the Framework for Improving quality that linked together the areas of work in Quality ...
Quality Improvement Division
core  

Methodological Quality of Cross-Cultural Adaptations of the American Orthopaedic Foot and Ankle Society Ankle-Hindfoot Scale

open access: yes
Background: The American Orthopaedic Foot and Ankle Society (AOFAS) scale is used to evaluate foot and ankle complaints, both in the general population and in athletes.
Marchena Rodríguez, Ana   +5 more
core   +1 more source

Methodological improvements are needed in network meta analyses of antidiabetic drugs for type 2 diabetes mellitus

open access: yesFrontiers in Endocrinology
IntroductionNumerous network meta-analyses have compared the efficacy of antidiabetic drugs for type 2 diabetes mellitus. However, a systematic assessment of their methodological and reporting quality remains lacking.MethodsWe searched the PubMed, Embase,
Anna Dai   +10 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Quality Improvement Division Operational Plan 2017

open access: yes, 2017
The Quality Improvement Division provides advice and support quality improvement projects and initiatives. We do this by partnering with frontline services however the implementation of these programmes remains with the leadership of frontline ...
Quality Improvement Division
core  

A Board's Role in Improving Quality and Safety - Guidance and Resources [PDF]

open access: yes, 2017
There are a number of key documents and resources applicable to boards and executives within healthcare in Ireland. This guidance builds on existing documentation and provides a central repository of international and national perspectives on the board’s
Quality Improvement Division
core  

Duration of immunity (protection from reinfection) following SARSCoV-2 infection [v8.0]

open access: yes, 2021
The Health Information and Quality Authority (HIQA) has developed a series of evidence syntheses to inform advice from HIQA to the National Public Health Emergency Team (NPHET). The advice takes into account expert interpretation of the evidence by HIQA’
Health Information and Quality Authority (HIQA)
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

National Quality Improvement Team Annual Report 2017

open access: yes, 2018
This report is a high level overview of work completed by the National Quality Improvement Team (formerly known as the Quality Improvement Division) in 2018.
National Quality Improvement Team
core  

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