Results 91 to 100 of about 578,219 (312)

Reliable enough to guide care? An umbrella review of hip arthroscopy meta‐analyses 2020–2025

Journal of Experimental Orthopaedics
Purpose Hip arthroscopy (HAS) evidence has expanded rapidly, but methodological quality and conclusions vary. This umbrella review of contemporary meta‐analyses published January 2020–October 2025 aimed to (i) identify eligible reviews, (ii) appraise ...
Nikolai Ramadanov, Maximilian Heinz, Maximilian Voss, Robert Prill, Roland Becker, Ingo J. Banke   +5 more
doaj   +1 more source

Economic evaluations of occupational health interventions from a corporate perspective – a systematic review of methodological quality

Scandinavian Journal of Work, Environment & Health, 2010
OBJECTIVE: Using a standardized quality criteria list, we appraised the methodological quality of economic evaluations of occupational safety and health (OSH) interventions conducted from a corporate perspective.
Kimi Uegaki, Martine C de Bruijne, Ludeke Lambeek, Johannes R Anema, Allard J van der Beek, Willem van Mechelen, Maurits W van Tulder   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Methodological quality graph.

, 2015
Our judgements for each methodological quality item are presented as percentages for all included studies.
Arnaud Fauconnier (400013), Viola Polena (696761), Roman Rouzier (78764), Cyrille Huchon (696762), Catalina Varas Ramos (696763), Alexandre Dumont (129216)   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

[¹⁸F]FDG PET/CT Radiomics in Cervical Cancer: A Systematic Review

Diagnostics
Background/Objectives: Cervical cancer is a significant global health concern, with high incidence and mortality rates, especially in less-developed regions.
Judicael Hotton, Arnaud Beddok, Abdenasser Moubtakir, Dimitri Papathanassiou, David Morland   +4 more
doaj   +1 more source

Effcacy and safety of nerve growth factor for the treatment of neurological diseases: a meta-analysis of 64 randomized controlled trials involving 6,297 patients

Neural Regeneration Research, 2015
OBJECTIVE: China is the only country where nerve growth factor is approved for large-scale use as a clinical medicine. More than 10 years ago, in 2003, nerve growth factor injection was listed as a national drug.
Meng Zhao, Xiao-yan Li, Chun-ying Xu, Li-ping Zou   +3 more
doaj   +1 more source

Conditions of The Life Quality – Methodological Remarks [PDF]

Economic and Environmental Studies, 2017
The life quality results from the degree of needs satisfaction, what comes among other from goods and services consumption. The aim of the work is to widespread the outcomes from author's research attempting to find the determinants of the life quality, using more advanced statistical methods.
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Percent used of methodological approaches for certainty and methodological quality assessment.

, 2022
(A) Methodological approaches for certainty of evidence assessment. (B) Methodological approaches for methodological quality assessment.
Nathorn Chaiyakunapruk (551390), Saranrat Sadoyu (12837158), Warittakorn Kategaew (12837170), Nai Ming Lai (6201473), Sobhon Paengtrai (12837167), Nattiwat Promchit (12837173), Ammarin Thakkinstian (840643), Surachat Ngorsuraches (719691), Nontaporn Punrum (12837164), Mukdarut Bangpan (6201476), Sajesh Veettil (3471701), Kaniz Afroz Tanni (12837161)   +11 more
core   +1 more source