Results 71 to 80 of about 578,219 (312)

Advancing occupational therapy scoping reviews: Recommendations to enhance quality and methodological rigour

Introduction Scoping reviews are an increasingly popular methodological approach to collate evidence and synthesise knowledge in many fields including occupational therapy. However, many are published with potential methodological weaknesses.
Gustafsson, Louise, McKinstry, Carol, Brown, Ted, Robinson, Luke   +3 more
core   +1 more source

Methodological quality and reporting of systematic reviews in hand and wrist pathology

, 2017
The objective of this study was to assess methodological and reporting quality of systematic reviews in hand and wrist pathology. MEDLINE, EMBASE and Cochrane Library were searched from inception to November 2016 for relevant studies.
J. Wasiak, O'Donohoe, TJ, Faggion Jr., Clovis M, T. J. O’Donohoe, R. Ware, C. M. Faggion, Wasiak, J, A. Y. Shen, Ware, Robert, Shen, AY   +9 more
core   +1 more source

Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis

Frontiers in Pharmacology
BackgroundDespite numerous systematic reviews (SRs) and meta-analyses (MAs) on natural product extracts (NPEs) for ischemic stroke, their methodological limitations and redundancy are unquantified, and the impact of the Preferred Reporting Items for ...
Sijin Wang, Minghui Zhang, Yao Lu, Peipei Du, Ziwen Xu, Xu Pang, Jierong Gao, Li Li, Chi Zhang, Chi Zhang   +9 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Methodological Quality of PROMs in Psychosocial Consequences of Colorectal Cancer Screening: A Systematic Review

, 2023
Emma Grundtvig Gram,1,2 Jessica á Rogvi,1 Anders Heiberg Agerbeck,1 Frederik Martiny,1 Anne Katrine Lykke Bie,1 John Brandt Brodersen1– 3 1The Center of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark ...
Gram EG, Bie AKL, Heiberg Agerbeck A, Brodersen JB, á Rogvi J, Martiny F   +5 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Methodological quality and reporting practices in gamification research for history education: a critical methodological analysis

Educational Technology Quarterly
Gamification has attracted growing research attention as an instructional strategy for history education, yet the methodological rigour of this evidence base has not been systematically evaluated.
Serhii S. Korniienko, Serhiy O. Semerikov   +1 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A Methodology For Quality Problems Diagnosis In Smes

, 2012
This article proposes a new methodology to be used by SMEs (Small and Medium enterprises) to characterize their performance in quality, highlighting weaknesses and area for improvement. The methodology aims to identify the principal causes of quality problems and help to prioritize improvement initiatives.
Teixeira, Humberto N., Lopes, Isabel da Silva, Sousa, Sérgio   +2 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source