Quality Assessment of Clinical Guidelines for Preventing Falls in Hospitalized Elderly People in Iran Using the Appraisal of Guidelines, Research, and Evaluation (AGREE) Checklist [PDF]
SālmandObjectives Hospitalization is a vulnerable period for the elderly. During this period, they are at risk of falling. There are various clinical guidelines for fall prevention, whose usefulness depends on their quality and clinical acceptance.
Mahsa Soleimani +2 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A 'quality revolution' constrained? A critical reflection on quality assurance methodology from the South African higher education context [PDF]
, 2010 This is an Accepted Manuscript of an article published by Taylor & Francis in Quality in Higher Education on 14 April 2010, available online: http://www.tandfonline.com/10.1080/13538321003679556.This paper attempts a brief meta-reflection on quality ...
Luckett, Kathy
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Importance of the distinction between quality of methodology and quality of reporting [PDF]
HPB, 2017 Altman, Douglas G. +2 more
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Critical appraisal of studies evaluating prevalence of attention deficit hyperactivity disorder
Frontiers in PsychiatryIntroductionAttention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder affecting an estimated 5–7% of children and adolescents and 2–5% of adults.
Michelle Tivadar +6 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
CSR communication research: A theoretical-cum-methodological perspective from semiotics [PDF]
, 2019 Despite the proliferation of studies on corporate social responsibility (CSR), there is a lack of consensus and a cardinal methodological base for research on the quality of CSR communication.
Omoteso, Kamil +2 more
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