Results 171 to 180 of about 8,171,446 (309)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Methodological quality of dental cone-beam CT diagnostic reference levels: a systematic review. [PDF]

Dentomaxillofac Radiol
Arunmani B, Horner K, Coleman R, Fleischmann I, McGuigan MB.   +4 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Environmental quality in Connecticut. 2013.

, 2014
Annual; Began with ...
Connecticut. Council on Environmental Quality.
core  

Clinical use of ozone therapy: a critical appraisal of evidence, safety, and methodological quality. [PDF]

Front Med (Lausanne)
Galassi FM, Zauli E, Vaccarezza M, Varotto E.   +3 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Social care division/quality improvement division QI programme newsletter April 2016

, 2016
Programme newsletter for the social care division/quality improvement division quality improvement ...
National Quality Improvement Team
core  

Methodological Quality of Prognostic Models for Periodontitis: A Systematic Review and Critical Appraisal. [PDF]

J Clin Periodontol
Karaban M, Dias DR, Troiano G, Baniameri S, Ahuja I, Joseph D, Serroni M, Ravidà A.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Methodological Quality and Health Equity of AI Prediction Models in Rectal Cancer. [PDF]

J Evid Based Med
Ye C, Wang Z, Wu Q, Lin G, Zhang C.
europepmc   +1 more source