Results 91 to 100 of about 1,338,720 (273)
The OBO Foundry: Coordinated Evolution of Ontologies to Support Biomedical Data Integration [PDF]
, 2007 The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data using common controlled vocabularies or ...
Ashburner, Michael +17 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Using agent based simulation to empirically examine complexity in carbon footprint business process [PDF]
, 2009 Through the critical analysis of the extant literature, it is observed that Simulation is widely used as a research method in Natural Sciences, Engineering and Social Sciences, in addition to argumentation and formalisation as the third way of carrying ...
Khan, T, Patel, NV, Pilla, VN
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Bioethics: Reincarnation of Natural Philosophy in Modern Science [PDF]
, 2017 The theory of evolution of complex and comprising of human systems and algorithm for its constructing are the synthesis of evolutionary epistemology, philosophical anthropology and concrete scientific empirical basis in ...
Cheshko, Valentin Teodorovich +2 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Following the central dogma: Nanopore sequencing from DNA and RNA to proteins
iScienceSummary: The first nanopore-based sequencer was launched in 2014, and subsequently, nanopore played an irreplaceable role in disclosing the first complete, gapless sequence of a human genome in 2022 due to its megabase-scale read lengths.
Yutong Wang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
An evaluation of the articulation of public policies on inclusive education in training of teachers at the State University of Maringá [PDF]
The article discusses the initial training of teachers from the perspective of inclusive education The current proposal for Inclusive Education is based on the Salamanca Declaration (Brazil, 1994a) - A document approved on 10 June 1994, at the World ...
Barros, Marcelo Alves +3 more
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