Results 41 to 50 of about 174,537,063 (257)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Unified Analysis of Stochastic Gradient Methods for Composite Convex and Smooth Optimization

open access: yes, 2023
We present a unified theorem for the convergence analysis of stochastic gradient algorithms for minimizing a smooth and convex loss plus a convex regularizer. We do this by extending the unified analysis of Gorbunov et al.
Nicolas Loizou   +9 more
core   +1 more source

Experimental and theoretical studies on (2E,5E)-2,5-bis(2-methoxybenzylidene)cyclopentanone: Structural, electrochemical, spectroscopic features, solid-state interactions, molecular docking and adsorption studies onto 2D carbon nanomaterials

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2023
A monocarbonyl analog of curcumin, (2E,5E)-2,5-bis(2-methoxybenzylidene)-cyclopentanone (B2MBCP), was prepared and characterized via spectroscopic methods (NMR, UV-Vis, FT-IR, and MS).
Veprim Thaçi   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Improving the quality of payment fraud detection by using a combined approach of transaction analysis

open access: yesСучасний стан наукових досліджень та технологій в промисловості
Subject matter: The study focuses on the methods for detection fraud transactions. Goal: Improve the accuracy of machine learning models for fraud transactions with combined methods for transaction analysis. Tasks: Investigate methods of detection fraud
Світлана Гавриленко   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Dai-Kou type conjugate gradient methods with a line search only using gradient

open access: yes, 2017
In this paper, the Dai-Kou type conjugate gradient methods are developed to solve the optimality condition of an unconstrained optimization, they only utilize gradient information and have broader application scope.
Changhe Liu, Yuanyuan Huang
core   +1 more source

Variable metric proximal stochastic variance reduced gradient methods for nonconvex nonsmooth optimization [PDF]

open access: yes, 2022
We study the problem of minimizing the sum of two functions. The first function is the average of a large number of nonconvex component functions and the second function is a convex (possibly nonsmooth) function that admits a simple proximal mapping ...
Dai, Y.H.   +7 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Class of Gradient-Type Methods with Perturbations

open access: yes, 2011
In this paper, a new kind of method which are called gradient-type method with perturbations are proposed and a new kind of nonmonotone line search technique is employed.
Mei Xia Li
core   +1 more source

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