ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos +10 more
wiley +1 more source
The Dynamics of Blood-Count-Derived Inflammatory Indices in the Course of Systemic Treatment for Psoriasis: A Single Center Study. [PDF]
Hołdrowicz A +4 more
europepmc +1 more source
Real‐world data on STRIDE‐II treatment targets in a pediatric cohort with inflammatory bowel disease
Abstract Objectives STRIDE (selecting therapeutic targets in inflammatory bowel disease) established evidence‐based targets for treat‐to‐target strategies in IBD. STRIDE‐II designates clinical remission, C‐reactive protein (CRP) normalization, and fecal calprotectin (FC) reduction as short‐ to intermediate‐term targets, and mucosal healing as a long ...
Marie‐Luise Frank +9 more
wiley +1 more source
Inflammatory indices, machine learning and artificial intelligence in tubal ectopic pregnancy management. [PDF]
Zorlu U +4 more
europepmc +1 more source
Correction to "Clinical Risk Factors for High-Dose Methotrexate-Induced Oral Mucositis Following Individualized Dosing". [PDF]
europepmc +1 more source
Validation of the MTXPK Tool in Predicting Glucarpidase Utilization Among Patients With Delayed Methotrexate Clearance: A Retrospective Study. [PDF]
Wu K, Dadeboyina C, Hua G.
europepmc +1 more source
Effectiveness and safety of ustekinumab in pediatric Crohn's disease: Results of the REALITI study
Abstract Objectives Few approved treatments exist for children with Crohn's disease (CD). The REALITI study retrospectively assessed the effectiveness and safety of ustekinumab in real‐world clinical settings for children with CD. Methods Data were collected from the prospective ImproveCareNow (ICN) registry for pediatric patients (≥ 2 to <18 years old)
Steven J. Steiner +60 more
wiley +1 more source
Drug Survival of Acitretin and Methotrexate in Adult Psoriasis Patients.
Erkayman MH, Ergun T.
europepmc +1 more source
Abstract Objectives Perianal abscesses (PA) and fistulas‐in‐ano (FIA) are frequently diagnosed in children and may be presenting symptoms of Crohn's disease (CD). The association between age at presentation of PA/FIA and the risk of subsequent CD development is largely unknown.
Mariëlle Roskam +13 more
wiley +1 more source

