Results 181 to 190 of about 271,187 (352)

PROLONGATION OF SKIN GRAFT SURVIVAL BY METHOTREXATE AND CROSS CIRCULATION

open access: bronze, 1965
Robert B. Epstein   +2 more
openalex   +1 more source

Methotrexate compared with placebo in lung cancer [PDF]

open access: bronze, 1977
Oleg S. Selawry   +9 more
openalex   +1 more source

A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane   +33 more
wiley   +1 more source

Population pharmacokinetic modelling of prednisolone in systemic lupus erythematosus patients: Analysis of exposure and disease activity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza   +26 more
wiley   +1 more source

High dose methotrexate with and without BCG therapy in advanced head and neck malignancy [PDF]

open access: bronze, 1979
Mary Buechler   +3 more
openalex   +1 more source

Mild psoriasis as a suitable model for proof‐of‐mechanism in a phase 1B setting: Results from a double‐blind placebo‐controlled trial with guselkumab

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Early clinical development of novel psoriasis therapies is hampered by a decreasing number of moderate‐to‐severe psoriasis patients eligible for participation in trials since efficacious treatments, such as biologics, have become widely available.
Jannik Rousel   +11 more
wiley   +1 more source

Effect of adriamycin and high-dose methotrexate chemotherapy onin vivo andin vitro cell-mediated immunity in cancer patients [PDF]

open access: bronze, 1978
Jack A. Roth   +2 more
openalex   +1 more source

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