Results 231 to 240 of about 180,290 (312)

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Dexpanthenol Attenuates Methotrexate-Induced Nephrotoxicity Through Modulation of NF-κB-Mediated Inflammation and SIRT1/PGC-1α-NRF2/HO-1-Associated Oxidative Stress Pathways. [PDF]

J Biochem Mol Toxicol
Altuntas A, Asci H, Selcuk E, Karaosman H, Aydin O, Ilhan I, Ozturk SA, Ozmen O.   +7 more
europepmc   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

Methotrexate toxicity due to a medication dispensing error compounded by an interaction with proton pump inhibitors. [PDF]

Toxicol Rep
Chakrabarti A, Pamarthi M, Bansal R, Chakrabarti SS, Kaur U.   +4 more
europepmc   +1 more source

Growth and development in paediatric onset inflammatory bowel disease: Data analysis from the CEDATA registry

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Different therapies may affect the growth and development of children and adolescents with inflammatory bowel disease (IBD) supporting specific therapy algorithms for paediatric Crohn's disease (CD) and ulcerative colitis (UC). Methods Growth and development data from the German–Austrian CEDATA‐GPGE registry entered between 2004 and ...
Ilse Broekaert, Anna Schmidt, Christoph Hünseler, Jan Delaffolie, CEDATA Study Group   +4 more
wiley   +1 more source

Effects of moxibustion on autophagy and ferroptosis in a disease-syndrome combination rat model of rheumatoid arthritis. [PDF]

Front Med (Lausanne)
Sang J, Jin Z, Zuo H, Zeng L, Yue Y, Wang M, Hu J, Hao F.   +7 more
europepmc   +1 more source

Association of attention‐deficit/hyperactivity disorder and autism with inflammatory bowel disease activity

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To estimate the effect of attention deficit hyperactivity disorder (ADHD) and autism on the disease activity of inflammatory bowel disease (IBD) in pediatric and young patients. Methods Patients diagnosed with IBD between the ages of 6 and 24 years were identified in Danish nationwide registries 1996–2022.
Sabine Jansson, Mads Damsgaard Wewer, Johan Burisch, Matthew P. Fox, Michael E. Benros, Charlotte Ulrikka Rask, Vibeke Wewer, Mikkel Malham   +7 more
wiley   +1 more source

Primary Burkitt lymphoma of the breast in a young north African woman: diagnostic challenge and benefit of early intensive chemotherapy. [PDF]

Oxf Med Case Reports
Ibtihal A, Bouanani N.
europepmc   +1 more source