Results 1 to 10 of about 1,282 (170)
Clinical and dermoscopic assessment of the efficacy of topical trichloroacetic acid 70% versus methoxsalen 0.2% paint in stable acral vitiligo [PDF]
Scientific ReportsLoss and absence of melanocytes due to a number of factors is responsible for vitiligo; known to be the commonest disorder of pigmentation. The aim of the study was to assess clinically and dermoscopically the efficacy of topical trichloroacetic acid 70%
Ahmed R. Elshahed +3 more
doaj +3 more sources
Methoxsalen-induced macular toxicity
Indian Journal of Ophthalmology, 2017 Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj +4 more sources
PLoS ONE, 2020 White-nose syndrome is a fungal disease responsible for the rapid decline of North American bat populations. This study addressed a novel method for inactivating Pseudogymnoascus destructans, the causative agent of WNS, using ultraviolet A (UVA) or B ...
Colin J Hartman +3 more
doaj +4 more sources
Protective Effects of Methoxsalen Supplementation on Chronic Alcohol-induced Osteopenia and Steatosis in Rats [PDF]
Molecules, 2020 Osteopenia or osteoporosis occurs frequently in alcoholics and patients with alcoholic fatty liver disease. Methoxsalen (MTS), 8-methoxypsoralen, improved osteoporosis in ovariectomized and diabetic mouse models; however, its effects on alcohol-induced ...
Ju Ri Ham +3 more
doaj +2 more sources
A randomized phase II study of SM‐88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond [PDF]
Cancer Medicine, 2022 Background This trial explores SM‐88 used with methoxsalen, phenytoin, and sirolimus (MPS) in pretreated metastatic pancreatic ductal adenocarcinoma (mPDAC) Methods Forty‐nine patients were randomized to daily 460 or 920 mg oral SM‐88 with MPS (SM‐88 ...
Marcus S. Noel +11 more
doaj +2 more sources
The Effect of Methoxsalen Dose on Ultraviolet-A-Induced Erythema [PDF]
Journal of Investigative Dermatology, 2001 There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen) after ingestion of the standard dose used in photochemotherapy (psoralen plus ultraviolet A). A dose change may be used to alter the degree of photosensitivity, although there is limited information on the effect of 8-methoxypsoralen dose alterations ...
Sally H. Ibbotson +2 more
openalex +5 more sources
Bulletin of the Chemical Society of Ethiopia, 2015 An accurate, simple and specific reverse phase LC procedure is established and validated for simultaneous estimation of methoxsalen and p-aminobenzoic acid in pharmaceutical formulated products and human serum.
P. John +5 more
doaj +3 more sources
The adverse effects of the methoxsalen and ultraviolent A radiation on spermatogenesis in mice [PDF]
Iranian Journal of Reproductive Medicine, 2015 Background: Different investigation showed that 5-methoxypsoralen and 8- methoxypsoralen reduce birth rates in the rats. Objective: In this study we worked out the effect of methoxsalen together with ultraviolent A (UVA) radiation on mature Balb/C mice ...
Mona Farhadi +4 more
doaj +1 more source
Oral methoxsalen photochemotherapy of mycosis fungoides [PDF]
Cancer, 1976 The cutaneous manifestations of mycosis fungoides have been successfully treated in nine patients for 16 to 28 months with oral methoxsalen and subsequent irradiation with longwave ultraviolet light. The efficacy of this therapy was confirmed in one patient, who showed complete clearing of generalized plaques after 1 month (12 treatments) except for a ...
Barbara A. Gilchrest +4 more
openalex +4 more sources
2441 Hepatotoxicity by Methoxsalen: The Innocuous Culprit
American Journal of Gastroenterology, 2019 INTRODUCTION: Drug-induced liver injury (DILI) is the second most common cause of acute liver failure; 15-20% cases of DILI can be attributed to damage caused by herbal or dietary supplements. Methoxsalen, commonly known as psoralen, is the active ingredient in Bakuchi seeds and is used for treatment of vitiligo and psoriasis ...
Amreet K. Aujla +4 more
openalex +4 more sources