Results 31 to 40 of about 2,112 (168)
Early and Late Side Effects Associated with Photo(chemo)therapy [PDF]
, 2010 Phototherapy (PUVA ve UVB) is a widely used and effective treatment method for a variety of dermatological diseases. Adverse effects associated with phototherapy can be classified as acute and chronic side effects.
Günseli Öztürk
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Photoinactivation of Skin Fibroblasts by Fractionated Treatment with 8-Methoxypsoralen and UVA [PDF]
, 1979 Guinea pig skin fibroblasts treated with low doses of 8-methoxypsoralen (8-MOP) and long-wave ultraviolet light (UVA) showed a dose-dependent inhibition of 3H-Thymidine incorporation as determined by liquid scintillation counting.
Christophers, Enno, Pohl, Joachim
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Natural Coumarins: QSTR Approaches Regarding Their Genotoxicity [PDF]
, 2015 The 18th International Electronic Conference on Synthetic Organic Chemistry session Computational ChemistryCoumarins are a group of phytochemicals with multiple applications in different fields, such as food and medicine. Many of their benefits are based
Abreu, Orlando +5 more
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Clinical Pharmacology &Therapeutics, Volume 116, Issue 4, Page 948-962, October 2024.The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the human CYP2A gene locus containing the highly polymorphic CYP2A6 gene. CYP2A6 plays a role in the metabolism of nicotine and various drugs. Thus, genetic variation can substantially contribute to the function of this enzyme and associated efficacy and safety.
Alec W.R. Langlois +9 more
wiley +1 more source
Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]
, 2009 In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho +3 more
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The Novel CYP2A6 Inhibitor, DLCI-1, Decreases Nicotine Self-Administration in Mice. [PDF]
, 2020 During tobacco and e-cigarette use, nicotine is mainly metabolized in the human liver by cytochrome P450 2A6 (CYP2A6). Given that a slower CYP2A6 metabolism has been associated with less vulnerability to develop nicotine dependence, the current studies ...
Chen, Yen-Chu +8 more
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Photoinactivation and Recovery in Skin Fibroblasts after Formation of Mono- and Bifunctional Adducts by Furocoumarins-Plus-UVA [PDF]
, 1980 Cultured skin fibroblasts from young male guinea pigs were irradiated with UVA light in the presence of 8-methoxypsoralen (8-MOP) or angelicin. As compared to 8-MOP 30 times higher concentrations of angelicin were needed to obtain comparative inhibition ...
Christophers, Enno, Pohl, Joachim
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Evaluation of cytotoxic effect of siphonochilone from African ginger: an in vitro analysis
Environmental Toxicology, Volume 39, Issue 9, Page 4333-4346, September 2024.Abstract Plants provide a wide array of compounds that can be explored for potential anticancer properties. Siphonochilone, a furanoterpene that represents one of the main components of the African plant Siphonochilus aethiopicus, shows numerous health benefits. However, to date, its antiproliferative properties have not been tested.
Alba Ortigosa‐Palomo +6 more
wiley +1 more source
Methoxsalen loaded chitosan coated microemulsion for effective treatment of psoriasis [PDF]
, 2011 Methoxsalen has been used for the treatment of psoriasis. In order to develop alternative formulations for the topical administration of methoxsalen, chitosan coated microemulsion were evaluated as delivery vehicle.
Behera, Jitendra +4 more
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Phototherapy for the treatment of cutaneous graft‐versus‐host disease: A systematic review
Photodermatology, Photoimmunology &Photomedicine, Volume 40, Issue 5, September 2024.Abstract Background Cutaneous graft‐versus‐host disease (GVHD) is a common complication of allogeneic hematopoietic stem cell transplantation. Phototherapy has been used to treat cutaneous GVHD, but data on its safety and efficacy are sparse. Aim Review the current medical literature regarding the efficacy, dosing, and safety of various types of ...
Tahel Fachler‐Sharp +6 more
wiley +1 more source