Results 31 to 40 of about 1,920 (175)

Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK) [PDF]

BMJ Open Respiratory Research
Background Long-term survival after lung transplantation is limited compared with other organ transplants. The main cause is development of progressive immune-mediated damage to the lung allograft.
Martin Carby, Jasvir Parmar, Andrew Bryant, Thomas Chadwick, Luke Vale, Catherine Exley, Andrew J Fisher, Helen Hancock, Richard Thompson, Joanne Lally, Andrew R Gennery, Michelle Bardgett, Siân Russell, Michael White, James MS Wason, Nicola Goudie, Anneka Kershaw, Julia Phillipson, Alex Bevin-Nicholls, Hesther Smith, Laura Frisby, Rebecca Errington, Karthik Santhanakrishnan   +22 more
doaj   +2 more sources

Dermoscopic Evaluation of the Efficacy of Topical Trichloroacetic acid 70% Versus Methoxsalen 0.2 % Paint in Acral Vitiligo, A comparative Cross-Sectional Study

Al-Azhar International Medical Journal
Ahmed Rashad Elshahid, Amr Mohammad Ammar, Abdallah Mamdouh lotfy Ali   +2 more
semanticscholar   +4 more sources

Methoxsalen

Reactions Weekly, 2006
europepmc   +4 more sources

Method Development and Validation of Methoxsalen

International Journal for Research in Applied Science and Engineering Technology, 2023
Bhagyashri Gayke
openalex   +2 more sources

EDA Complex-Driven Desaturation of Heterocyclic Carbonyl Compounds Enabled by HFIP. [PDF]

Angew Chem Int Ed Engl
In this work, we report a novel light‐mediated desaturation strategy enabled by electron donor–acceptor complex formation. DFT and mechanistic studies reveal that the reaction proceeds via single‐electron transfer, hydrogen atom transfer, and base‐mediated deprotonation sequentially with pyridinium salt serving dually as oxidant and base, and ...
Maiti R, Cauwenbergh R, Nath A, Guimarães ABR, Qin Y, Maseras F, Das S.   +6 more
europepmc   +3 more sources

Single-Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions. [PDF]

JOR Spine
IVDD has various NPC subgroups, including HT‐CLNP, fibrous NPC, sticky NPC, regulatory NPC, and steady‐state NPC. Furthermore, numerous immune cell infiltrates, particularly monocytes and macrophages, play a crucial role in the evolution of IVDD. Parthenogenesis' key components are Osthole, Columbianadin, and Bergapten, which absorb IVDD by managing ...
Song C, Wu X, Chen C, Shen B, Mei Y, Yan Q, Jiang F, Chen F, Liu F.   +8 more
europepmc   +2 more sources

Dehydrocostus Lactone Inhibits Microglia‐Mediated Neuroinflammation by Targeting CYP2A6 to Improve Ischemic Brain Injury [PDF]

CNS Neurosci Ther
Dehydrocostus lactone (DHC) inhibits microglia‐mediated neuroinflammation by targeting CYP2A6, reducing the release of pro‐inflammatory factors and improving nerve function impairment, thereby alleviating ischemic brain injury. ABSTRACT Background Neuroinflammation is an important factor in ischemic stroke.
Shu X, Zou X, Zhang J, Fang X, Wang X, Wu H, He X, Sha D.   +7 more
europepmc   +2 more sources

New Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization

Frontiers in Chemistry, 2022
In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time.
Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Raman Gurusamy, Akbar Idhayadhulla, Radhakrishnan Surendrakumar   +6 more
doaj   +1 more source

Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor [PDF]

Nicotine & Tobacco Research, 2013
Shakir D. AlSharari, Eric Siu, Rachel F. Tyndale, M. Imad Damaj   +3 more
openalex   +2 more sources

A Study of the Furocoumarin Derivative of Ruta Chalepensis L. (Rutaceae)

Iraqi Journal of Pharmaceutical Sciences, 2017
The content of Furocoumarin derivatives (Psoralens) of Ruta Chalepensis L. (Whole plant) was studied by simple extraction with petroleum ether (b.p. 60-80Co).
Ekbal H.AL-Khateeb, Ali A. AL-Shamma, Bajes A. Nehar   +2 more
doaj   +3 more sources