Results 31 to 40 of about 1,282 (170)

Mycosis Fungoides in Paediatric Patients: A Real‐Life Retrospective Study

JEADV Clinical Practice, Volume 4, Issue 4, Page 783-790, September 2025.
Our study represents the largest cohort of children with MF worldwide, providing relevant evidence supporting phototherapy as first‐line treatment, with an overall remission rate of 36.36%. Both topical and systemic therapy also showed favourable outcomes.
Mariana de la Vega, María Antonieta Domínguez Gómez, Martha Alejandra Morales‐Sánchez   +2 more
wiley   +1 more source

Extraction, Isolation, and Purification of Furanocoumarins from Invasive Heracleum sosnowskyi

Separations
Heracleum sosnowskyi Manden. (Sosnowsky’s hogweed), originally introduced to Central and Eastern Europe as a fodder crop, has become a highly invasive species due to its ecological adaptability, high reproductive capacity, and efficient seed dispersal ...
Vida Vickackaite, Karina Pilaityte, Vilius Poskus   +2 more
doaj   +1 more source

In Vitro Investigation of the Cytotoxic and Antioxidant Activities of Ardisia polycephala, Iresine herbstii, and Oenanthe javanica Extracts With Potential Applications in Breast Cancer Therapy

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Ardisia polycephala, Iresine herbstii, and Oenanthe javanica are commonly used to nourish women’s blood and treat reproductive system diseases, according to Thai Traditional Medicine (TTM) scriptures. This study explores the biological activities of these herbs as documented in TTMs.
Nuntika Prommee, Ubonwan Saesiw, Thana Juckmeta, Pakakrong Thongdeeying, Kitiya Yangthaworn, Bhanuz Dechayont, Jitpisute Chunthorng-Orn, Pathompong Phuaklee, Tassanee Ongtanasup, Onmanee Prajuabjinda, Ezzouhra Elmaaiden   +10 more
wiley   +1 more source

Melanocyte transplantation to skin prepared by controlled PUVA-induced sunburn-like blistering for vitiligo treatment – A pilot clinical trial

Journal of the Formosan Medical Association
Vitiligo is a common acquired disease of pigment loss. In lesions recalcitrant to non-invasive treatment, transplantation of cultured autologous melanocytes is an emerging choice.
Po-Hua Chen, Sabrina Mai-Yi Fan, Bin-Ru She, Yi-Ping Wu, Hsiang-Chun Hsu, Ying-Jung Yang, Jun-Jae Huang, Shu-Fen Yeh, Yi-Chen Chen, Pei-Ju Lin, Wann-Hsin Chen, Hsien-Ching Chiu, Hsin-Su Yu, Chih-Ching Liao, Sung-Jan Lin   +14 more
doaj   +1 more source

PharmVar GeneFocus: CYP2A6

Clinical Pharmacology &Therapeutics, Volume 116, Issue 4, Page 948-962, October 2024.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the human CYP2A gene locus containing the highly polymorphic CYP2A6 gene. CYP2A6 plays a role in the metabolism of nicotine and various drugs. Thus, genetic variation can substantially contribute to the function of this enzyme and associated efficacy and safety.
Alec W.R. Langlois, Meghan J. Chenoweth, David Twesigomwe, Giada Scantamburlo, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Charity Nofziger, Rachel F. Tyndale, Andrea Gaedigk   +9 more
wiley   +1 more source

Evaluation of cytotoxic effect of siphonochilone from African ginger: an in vitro analysis

Environmental Toxicology, Volume 39, Issue 9, Page 4333-4346, September 2024.
Abstract Plants provide a wide array of compounds that can be explored for potential anticancer properties. Siphonochilone, a furanoterpene that represents one of the main components of the African plant Siphonochilus aethiopicus, shows numerous health benefits. However, to date, its antiproliferative properties have not been tested.
Alba Ortigosa‐Palomo, David Fuentes‐Ríos, Francisco Quiñonero, Consolación Melguizo, Raul Ortiz, Juan M. López‐Romero, Jose Prados   +6 more
wiley   +1 more source

Phototherapy for the treatment of cutaneous graft‐versus‐host disease: A systematic review

Photodermatology, Photoimmunology &Photomedicine, Volume 40, Issue 5, September 2024.
Abstract Background Cutaneous graft‐versus‐host disease (GVHD) is a common complication of allogeneic hematopoietic stem cell transplantation. Phototherapy has been used to treat cutaneous GVHD, but data on its safety and efficacy are sparse. Aim Review the current medical literature regarding the efficacy, dosing, and safety of various types of ...
Tahel Fachler‐Sharp, Inbar Kobal, Sivan Sheffer‐Levi, Adiel Cohen, Ayal Hassidim, Vered Molho‐Pessach, Rony Shreberk‐Hassidim   +6 more
wiley   +1 more source

Deuterated Alkyl Sulfonium Salt Reagents; Importance of H/D Exchange Methods in Drug Discovery

ChemMedChem, Volume 19, Issue 16, August 19, 2024.
Recently, deuterated drugs have been highlighted as a new modality, and H/D exchange reactions are powerful and straightforward synthetic tools. We have successfully established a novel concept to diversify deuterium drug discovery using dn‐alkylation reagents (dn‐alkyl diphenylsulfonium salts) with excellent D contents and perfect site selectivity ...
Riku Ogasahara, Kazuho Ban, Miyu Mae, Shuji Akai, Yoshinari Sawama   +4 more
wiley   +1 more source

8-methoxsalen photochemistry enhances tumor cell immunogenicity by inducing ferroptosis in B16 cells

Zhongguo shuxue zazhi
[Objective] To study the efficacy of photosensitizer 8- methoxsalen (8-MOP) combined with ultraviolet radiation A (UVA) in inducing ferroptosis in mouse melanoma B16 cells, and to assess the resultant changes in immunogenicity, and their impact on ...
ZHONG Yan, LIN Yuwei, CHEN Wei, TIAN Li, LI Ling, LIU Zhong   +5 more
doaj   +1 more source

Primary cutaneous plasmacytosis successfully treated with topical corticosteroids and psoralen plus ultraviolet A: A case report

Clinical Case Reports, Volume 12, Issue 3, March 2024.
Key clinical message We present a case of primary cutaneous plasmacytosis without systemic involvement. The patient received topical corticosteroids and psoralen plus ultraviolet A therapy, showing significant improvement. Continuous monitoring is underway despite the rarity of systemic manifestations.
Thanyathorn Nuchanatanon, Settanan Plangsiri, Teerapong Rattananukrom   +2 more
wiley   +1 more source