Results 31 to 40 of about 2,832 (233)
Pentafluorocyclopropanation of (Hetero)arenes Using Sulfonium Salts: Applications in Late‐Stage Functionalization
Angewandte Chemie, Volume 135, Issue 35, August 28, 2023., 2023 An unprecedented sulfonium salt is presented, which under mild photochemical conditions, is able to transfer pentafluorocyclo‐propenyl groups (C3F5−) at unfunctionalized positions of a number of (hetero)arenes. The reaction is compatible with a variety of functional groups, rendering this method a practical tool for future drug optimization campaigns ...Zeyu Feng, Lucas Riemann, Zichen Guo, David Herrero, Martin Simon, Christopher Golz, Ricardo A. Mata, Manuel Alcarazo +7 morewiley +2 more sourcesNew Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization
Frontiers in Chemistry, 2022 In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time.Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Raman Gurusamy, Akbar Idhayadhulla, Radhakrishnan Surendrakumar +6 moredoaj +1 more sourceExtracorporeal photopheresis induces NETosis in neutrophils derived from patients with chronic graft‐vs‐host disease
Journal of Clinical Apheresis, Volume 38, Issue 5, Page 615-621, October 2023., 2023 Abstract Introduction
Extracorporeal photopheresis (ECP) is considered an effective treatment for patients with chronic graft vs host disease (cGVHD) and demonstrates efficacy in ameliorating GVHD. The mechanism by which ECP acts against cGVHD is not fully understood.Idan Goldberg, Galit Granot, Alona Telerman, Shirly Partouche, Tzippy Shochat, Erez Halperin, Anat Gafter‐Gvili, Liat Shargian, Moshe Yeshurun, Pia Raanani, Ofir Wolach, Vered Yahalom +11 morewiley +1 more sourceThe Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.Stephen P. H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Deron Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Davide Malfacini, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Philippe Rondard, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Khuraijam Dhanachandra Singh, Craig M. Smith, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Chengcan Yao, Richard D. Ye +165 morewiley +1 more sourceThe Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]
, 2016 BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...Abrouk, Michael, Bhutani, Tina, DaLovisio, Renee, Farahnik, Benjamin, Jose, Margareth V, Koo, John, Lee, Kristina M, Liao, Wilson, Nakamura, Mio, Singh, Rasnik K, Zhu, Tian Hao +10 morecore +3 more sourcesNb‐UVB and PUVA therapy in treating early stages of Mycosis Fungoides: A single‐center cross‐sectional study
Photodermatology, Photoimmunology &Photomedicine, Volume 39, Issue 5, Page 435-440, September 2023., 2023 Abstract Introduction
Mycosis fungoides (MF) and Sezary Syndrome are the most common forms of cutaneous T‐cell lymphoma. Early‐stage MF is known to have an indolent behavior, and the EORTC guidelines recommend treating patients with skin‐directed therapies, such as phototherapy, instead of systemic therapies.Corrado Zengarini, Gregorio Baruffaldi, Bianca Maria Piraccini, Federico Bardazzi, Martina Mussi, Bor Hrvatin Stancic, Alessandro Pileri +6 morewiley +1 more sourceMolecular Mechanisms Associated with Nicotine Pharmacology and Dependence. [PDF]
, 2020 Tobacco dependence is a leading cause of preventable disease and death worldwide. Nicotine, the main psychoactive component in tobacco cigarettes, has also been garnering increased popularity in its vaporized form, as derived from e-cigarette devices ...A Ashoor, A Kuryatov, A Loukola, A Loukola, A Markou, A Pandhare, AA George, AA Strasser, AB Tekinay, AC Harris, AC Villanti, AJ Lanca, AJ Law, AK Stoker, AR Tapper, AT Peana, B Forget, B Froeliger, B Le Foll, B Lenz, BJ Hall, BJ Henderson, CD Fowler, CD Fowler, CDC, CJ Livingston, CL Walters, CL Walters, CM Flores, D Bagdas, D Carmelli, D Gonzales, D Ji, D John, D Vullhorst, DB Vazquez-Sanroman, DC Perry, DK Williams, E Wada, EC Pittaras, ED Claus, EE DeVito, EJ Nestler, EN Lyukmanova, FI Carroll, FJ McClernon, G Di Chiara, G Kong, G Schoenbaum, GS Portugal, H Xian, HD Mansvelder, I Ibanez-Tallon, J Hartmann-Boyce, J Hartmann-Boyce, J Ramirez-Latorre, J Tang, JA Dani, JA Dani, JA Hill Jr, JA Wilking, JE Lisman, JJ Couey, JM Miwa, JM Miwa, JM Miwa, JM Williams, JP Changeux, JR Turner, JR Turner, JR Turner, JS Fowler, JS Fowler, JW Kenney, JZ Liu, KA Garrison, KJ Clemens, KJ Jackson, KJ Jackson, KJ Jackson, KJ Jackson, KP Cosgrove, KS Kendler, KS Okuyemi, L Lagostena, L Zhou, LJ Bierut, LM Tuesta, LP Dwoskin, LP Dwoskin, M Alkondon, M Alkondon, M Arvaniti, M De Biasi, M Foddai, M Kallupi, M Kassiou, M Yuan, M Zhang, MD Li, MI Damaj, MJ Marks, MJ Orejarena, ML Fisher, ML Goniewicz, MP Demars, MR Picciotto, MS Thomsen, MT Bardo, N Champtiaux, N Omelchenko, NI Nissen, NL Benowitz, NL Saccone, O Salminen, P Fagan, P Li, P Truman, PF Sullivan, PJ Welsby, R Girod, R Klink, R Miech, R Salas, R Srinivasan, RL Ashare, RS Caraballo, S Dodd, S Jones, S Kuhn, S Nakauchi, S Pons, S Tonstad, SD Alsharari, SD Alsharari, SS Sanjakdar, TT Smith, U Broms, U Maskos, V Gerzanich, W Berrettini, WA Corrigall, WD Myers, X Pang, Y Li, YY Huang, Z Jin +146 morecore +1 more source
