Results 41 to 50 of about 1,920 (175)

Novel psoralen derivatives as anti-breast cancer agents and their light-activated cytotoxicity against HER2 positive breast cancer cells

open access: yesScientific Reports, 2022
Psoralen derivatives are well known for their unique phototoxicity and also exhibits promising anti-breast cancer activity both in the presence and the absence of UVA irradiation.
Chiphada Aekrungrueangkit   +7 more
doaj   +1 more source

The Adverse Effects of Methoxsalen on The Oogenesis of Balb/C Mice [PDF]

open access: yesCell Journal, 2013
Objective: Methoxsalen is a natural photoactive compound which is found in many seed plants. A number of epidermal proliferative disorders can be treated by methoxsalen along with long wave ultraviolet A (UVA).Materials and Methods: In an experimental ...
Abbas Shockravi   +4 more
doaj  

FOTOFÉRESE EXTRACORPÓREA – PRIMEIRO PROCEDIMENTO REALIZADO NO SERVIÇO DE AFÉRESE DO BANCO DE SANGUE DO HOSPITAL SANTA MARCELINA – RELATO DE CASO

open access: yesHematology, Transfusion and Cell Therapy, 2021
Introdução: Fotoférese Extracorpórea (FEC) se baseia na manipulação dos linfócitos T com substâncias fotossensibilizantes que quando expostos à luz ultravioleta (UV) sofrem apoptose e ao serem devolvidos ao paciente desencadeiam uma série de efeitos ...
ST Alves   +5 more
doaj   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Exposure Registries as a Prevention Tool for Occupational Cancers: Establishing a New Hazardous Drug Registry for Oncology Personnel

open access: yesAmerican Journal of Industrial Medicine, Volume 68, Issue 12, Page 1037-1047, December 2025.
ABSTRACT Public health registries collect and maintain demographic and health data on a cohort of people with a common disease or exposure. While disease registries have proliferated in recent decades, registries comprising persons with potentially hazardous exposures—known commonly as exposure registries—are rare.
Sammy Almashat   +3 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Breast and Nipple Dermatoses During Lactation

open access: yesAustralasian Journal of Dermatology, Volume 66, Issue 7, Page e386-e407, November 2025.
ABSTRACT Lactation and breastfeeding can present both psychological and physical challenges for breastfeeding mothers. In addition, many nursing mothers will also suffer from breast and nipple dermatoses during this period, compounding these difficulties. Common causes of breast and nipple dermatitis during lactation include eczema, psoriasis, mastitis,
Hamish Moore, Annabel Stevenson
wiley   +1 more source

Mycosis Fungoides in Paediatric Patients: A Real‐Life Retrospective Study

open access: yesJEADV Clinical Practice, Volume 4, Issue 4, Page 783-790, September 2025.
Our study represents the largest cohort of children with MF worldwide, providing relevant evidence supporting phototherapy as first‐line treatment, with an overall remission rate of 36.36%. Both topical and systemic therapy also showed favourable outcomes.
Mariana de la Vega   +2 more
wiley   +1 more source

In Vitro Investigation of the Cytotoxic and Antioxidant Activities of Ardisia polycephala, Iresine herbstii, and Oenanthe javanica Extracts With Potential Applications in Breast Cancer Therapy

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Ardisia polycephala, Iresine herbstii, and Oenanthe javanica are commonly used to nourish women’s blood and treat reproductive system diseases, according to Thai Traditional Medicine (TTM) scriptures. This study explores the biological activities of these herbs as documented in TTMs.
Nuntika Prommee   +10 more
wiley   +1 more source

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