Results 31 to 40 of about 72,007 (341)

Cyanovinylation of Aldehydes: Organocatalytic Multicomponent Synthesis of Conjugated Cyanomethyl Vinyl Ethers

open access: yesMolecules, 2021
A novel organocatalytic multicomponent cyanovinylation of aldehydes was designed for the synthesis of conjugated cyanomethyl vinyl ethers. The reaction was implemented for the synthesis of a 3-substituted 3-(cyanomethoxy)acrylates, using aldehydes as ...
Samuel Delgado-Hernández   +2 more
doaj   +1 more source

High turnover in electro-oxidation of alcohols and ethers with a glassy carbon-supported phenanthroimidazole mediator. [PDF]

open access: yes, 2017
Glassy carbon electrodes covalently modified with a phenanthroimidazole mediator promote electrochemical alcohol and ether oxidation: three orders of magnitude increase in TON, to ∼15 000 in each case, was observed compared with homogeneous mediated ...
Berben, Louise A   +3 more
core   +1 more source

Bile acids. OV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid.

open access: yesJournal of Lipid Research, 1978
Artifacts formed by methylation of chenodeoxycholic acid with diazomethane are identical to the synthetic 3alpha- and 7 alpha-monomethyl ethers of methyl chenodeoxycholate. The extent of formation of these artifacts with time has been studied.
R Shaw, W H Elliott
doaj   +1 more source

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

Heterogeneous acidic catalysts for the tetrahydropyranylation of alcohols and phenols in green ethereal solvents

open access: yesBeilstein Journal of Organic Chemistry, 2018
The application of heterogeneous catalysis and green solvents to the set up of widely employed reactions is a challenge in contemporary organic chemistry. We applied such an approach to the synthesis and further conversion of tetrahydropyranyl ethers, an
Ugo Azzena   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Factors Dictating Carbene Formation at (PNP)Ir [PDF]

open access: yes, 2010
The mechanistic subtleties involved with the interaction of an amido/bis(phosphine)-supported (PNP)Ir fragment with a series of linear and cyclic ethers have been investigated using density functional theory.
Ariafard, Alireza   +5 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

New [4 + 2] Cycloadditions of in situ Generated Indolyl Enol Ethers and Their Anions with Dimethyl Acetylenedicarboxylate: A One-Pot Access to 4-Alkoxy-Substituted Carbazoles

open access: yesCHIMIA, 1992
The 3-indolyl(methyl)methoxycarbenium tetrafluoroborates 1a?d were deprotonated with NaH to furnish in situ the highly reactive 3-indolyl enol ethers 2a or their corresponding 3-indolyl enol ether anions 2b.
Ulf Pindur, Martina Rogge
doaj   +2 more sources

High-performance liquid chromatographic separation of surface flavonoid aglycones in Artemistia annua L. and Artemisia vulgaris L [PDF]

open access: yesJournal of the Serbian Chemical Society, 2004
External flavonoid aglycones from Artemisia annua L. and Artemisia vulgaris L. were analyzed by the HPLC method. The mobile phase was composed of t-butanol-methanol- 20 mmol l-1 phosphate buffer, pH 3.22.
Nikolova Milena   +2 more
doaj   +1 more source

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