Results 11 to 20 of about 911,489 (397)

The Effect of Contrast Enhanced Abdominopelvic Magnetic Resonance Imaging on Expression and Methylation Level of ATM and AKT Genes [PDF]

open access: yesCell Journal, 2021
Objective: To evaluate the effect of contrast enhanced abdominopelvic magnetic resonance imaging (MRI), using a 3 Tesla scanner, on expression and methylation level of ATM and AKT genes in human peripheral blood lymphocytes.
Amir Hossein Jalali   +2 more
doaj   +1 more source

DNA Methylation [PDF]

open access: yesEcoSal Plus, 2009
The DNA of Escherichia coli contains 19,120 6-methyladenines and 12,045 5-methylcytosines in addition to the four regular bases, and these are formed by the postreplicative action of three DNA methyltransferases. The majority of the methylated bases are formed by the Dam and Dcmmethyltransferases encoded by the
Marinus, Martin G.   +1 more
openaire   +4 more sources

High Expression of CLEC11A Predicts Favorable Prognosis in Acute Myeloid Leukemia

open access: yesFrontiers in Oncology, 2021
BackgroundAcute myeloid leukemia (AML) is a heterogeneous disease of the hematopoietic system, for which identification of novel molecular markers is potentially important for clinical prognosis and is an urgent need for treatment optimization.MethodsWe ...
Chengliang Yin   +14 more
doaj   +1 more source

A Novel Prognostic Model of Early-Stage Lung Adenocarcinoma Integrating Methylation and Immune Biomarkers

open access: yesFrontiers in Genetics, 2021
Lung adenocarcinoma (LUAD) is caused by multiple biological factors. Therefore, it will be more meaningful to study the prognosis from the perspective of omics integration.
Jin Ren   +8 more
doaj   +1 more source

Methyl 4-methylbenzoate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2008
The structure of the title compound, C(9)H(10)O(2), is related to that of 4-methyl-phenyl 4-methyl-benzoate and ethyl-ene di-4-methyl-benzoate showing similar bond parameters. The mol-ecule is planar, the dihedral angle between the aromatic ring and the -COOMe group being 0.95 (6)°. The cystal structure exhibits inter-molecular C-H⋯O contacts that link
Hummera Rafique   +2 more
openaire   +4 more sources

Pharmacokinetic study of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement product

open access: yesBMC Pharmacology and Toxicology, 2020
Background A novel, high bioavailability oral, enteric coated tablet formulation of S-adenosylmethionine (MSI-195) has been developed for life science application.
Beth R. Cameron   +2 more
doaj   +1 more source

A Feature Selection Algorithm to Compute Gene Centric Methylation from Probe Level Methylation Data [PDF]

open access: yes, 2016
DNA methylation is an important epigenetic event that effects gene expression during development and various diseases such as cancer. Understanding the mechanism of action of DNA methylation is important for downstream analysis.
Baur, Brittany, Bozdag, Serdar
core   +13 more sources

Promoter Methylation Leads to Decreased ZFP36 Expression and Deregulated NLRP3 Inflammasome Activation in Psoriatic Fibroblasts

open access: yesFrontiers in Medicine, 2021
The mRNA-destabilizing protein tristetraprolin (TTP), encoded by the ZFP36 gene, is known to be able to end inflammatory responses by directly targeting and destabilizing mRNAs encoding pro-inflammatory cytokines.
Matteo Bertesi   +10 more
doaj   +1 more source

Epigenetic impact of the parents' physical activity on the health of their children

open access: yesBaltic Journal of Health and Physical Activity, 2021
All parents’ dream is to have healthy children. The question whether the parents' lifestyle affects the quality of their progeny's health has been bothering scientists and society for many years.
AGNIESZKA BORON
doaj   +1 more source

Whole-Genome Methylation Study of Congenital Lung Malformations in Children

open access: yesFrontiers in Oncology, 2021
Background and ObjectivesThe treatment of asymptomatic patients with congenital pulmonary malformations (CPMs) remains controversial, partially because the relationship between congenital lung malformations and malignancy is still undefined.
Sara Patrizi   +3 more
doaj   +1 more source

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