Results 21 to 30 of about 1,023,442 (398)

A Novel Prognostic Model of Early-Stage Lung Adenocarcinoma Integrating Methylation and Immune Biomarkers

open access: yesFrontiers in Genetics, 2021
Lung adenocarcinoma (LUAD) is caused by multiple biological factors. Therefore, it will be more meaningful to study the prognosis from the perspective of omics integration.
Jin Ren   +8 more
doaj   +1 more source

Methyl 4-methylbenzoate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2008
The structure of the title compound, C(9)H(10)O(2), is related to that of 4-methyl-phenyl 4-methyl-benzoate and ethyl-ene di-4-methyl-benzoate showing similar bond parameters. The mol-ecule is planar, the dihedral angle between the aromatic ring and the -COOMe group being 0.95 (6)°. The cystal structure exhibits inter-molecular C-H⋯O contacts that link
Hummera Rafique   +2 more
openaire   +4 more sources

Pharmacokinetic study of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement product

open access: yesBMC Pharmacology and Toxicology, 2020
Background A novel, high bioavailability oral, enteric coated tablet formulation of S-adenosylmethionine (MSI-195) has been developed for life science application.
Beth R. Cameron   +2 more
doaj   +1 more source

The role of m6A RNA methylation in cancer metabolism

open access: yesMolecular Cancer, 2022
Metabolic reprogramming is one of the main characteristics of malignant tumors, which is due to the flexible changes of cell metabolism that can meet the needs of cell growth and maintain the homeostasis of tissue environments.
Yuanyuan An, Huayan Duan
semanticscholar   +1 more source

Promoter Methylation Leads to Decreased ZFP36 Expression and Deregulated NLRP3 Inflammasome Activation in Psoriatic Fibroblasts

open access: yesFrontiers in Medicine, 2021
The mRNA-destabilizing protein tristetraprolin (TTP), encoded by the ZFP36 gene, is known to be able to end inflammatory responses by directly targeting and destabilizing mRNAs encoding pro-inflammatory cytokines.
Matteo Bertesi   +10 more
doaj   +1 more source

Epigenetic impact of the parents' physical activity on the health of their children

open access: yesBaltic Journal of Health and Physical Activity, 2021
All parents’ dream is to have healthy children. The question whether the parents' lifestyle affects the quality of their progeny's health has been bothering scientists and society for many years.
AGNIESZKA BORON
doaj   +1 more source

Methyl eucomate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2008
THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: methyl 3-carboxy-3-hydr-oxy-3-(4-hydroxy-benz-yl)propanoate], C(12)H(14)O(6), is stabilized by inter-molecular O-H⋯O and C-H⋯O hydrogen bonds. The mol-ecules are arranged in layers, parallel to (001), which are inter-connected by the O-H⋯O hydrogen bonds.
Linglin Li   +2 more
openaire   +3 more sources

Whole-Genome Methylation Study of Congenital Lung Malformations in Children

open access: yesFrontiers in Oncology, 2021
Background and ObjectivesThe treatment of asymptomatic patients with congenital pulmonary malformations (CPMs) remains controversial, partially because the relationship between congenital lung malformations and malignancy is still undefined.
Sara Patrizi   +3 more
doaj   +1 more source

Imprinted Genes Impact Upon Beta Cell Function in the Current (and Potentially Next) Generation

open access: yesFrontiers in Endocrinology, 2021
Beta cell failure lies at the centre of the aetiology and pathogenesis of type 2 diabetes and the epigenetic control of the expression of critical beta cell genes appears to play a major role in this decline.
Chelsie Villanueva-Hayes   +1 more
doaj   +1 more source

Synthesis of (.+-.)-methyl epijasmonate and (.+-.)-methyl cucurbate. [PDF]

open access: yesAgricultural and Biological Chemistry, 1987
A novel synthesis of ( ± )-methyl epijasomonate (2) and the first synthesis of ( ± )-methyl cucurbate (4) were achieved starting from 2-allylcyclohexane-1,3-dione (8). The synthetic epimer 2 had a stronger jasmin flavor than the trans-isomer 1 with 95% purity.
Katsutoshi Miura   +4 more
openaire   +2 more sources

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