Results 31 to 40 of about 641,368 (381)
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences of the United States of America, 1996 Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes such as the regulation of imprinted genes, X chromosome inactivation, and tumor suppressor gene silencing in human cancer.
J. Herman +4 more
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Expression and Methylation of PDCD4 in Gastric Carcinoma and Its Clinical Significance
Zhongliu Fangzhi Yanjiu, 2020 Objective To observe the methylation status of the promoter region of the tumor suppressor gene PDCD4 in gastric cancer tissues and its effect on the expression level of PDCD4, and to explore its clinical significance.
BA He, PENG Qiang, ZHU Yaodong
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Frontiers in Genetics, 2021 The appearance of tyrosine kinase inhibitors (TKIs) has been a major breakthrough in renal cell carcinoma (RCC) therapy. Unfortunately, a portion of patients with TKIs resistance experience disease progression after TKIs therapy.
Qinhan Li +3 more
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Acta Crystallographica Section E Structure Reports Online, 2009 THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND (SYSTEMATIC NAME: methyl 3,4,5-trihydroxy-benzoate), C(8)H(8)O(5), is composed of essentially planar mol-ecules [maximum departures from the mean carbon and oxygen skeleton plane of 0.0348 (10) Å]. The H atoms of the three hydroxyl groups, which function as hydrogen-bond donors and acceptors simultaneously ...
Silvina Pagola, Deborah Bebout
openaire +3 more sources
Higher order methylation features for clustering and prediction in epigenomic studies [PDF]
Bioinformatics (2016) 32 (17): i405-i412, 2016 Motivation: DNA methylation is an intensely studied epigenetic mark, yet its functional role is incompletely understood. Attempts to quantitatively associate average DNA methylation to gene expression yield poor correlations outside of the well-understood methylation-switch at CpG islands.
arxiv +1 more source
Bioinform., 2014 MOTIVATION The recently released Infinium HumanMethylation450 array (the '450k' array) provides a high-throughput assay to quantify DNA methylation (DNAm) at ∼450 000 loci across a range of genomic features.
Martin J. Aryee +6 more
semanticscholar +1 more source
Beilstein Journal of Organic Chemistry, 2019 (2Z,4E)-3-Methyl-2,4-decadienoic acid (1) was identified as a major metabolite from a culture extract of a marine bacterium Microbulbifer which was collected from a stony coral Porites sp.
Amit Raj Sharma +4 more
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Frontiers in Oncology, 2021 The effective management of biliary tract cancers (BTCs) has been hampered by limited options for systemic therapy. In recent years, the focus on precision medicine has made technologies such as next-generation sequencing (NGS) accessible to clinicians ...
Ashish Manne +3 more
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DNA methylation GrimAge strongly predicts lifespan and healthspan
Aging, 2019 It was unknown whether plasma protein levels can be estimated based on DNA methylation (DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful predictor of lifespan.
A. Lu +13 more
semanticscholar +1 more source
International Journal of General Medicine, 2021 Junwei Tong,1– 3,* Xiangui Meng,1– 3,* Qingyang Lv,1– 3,* Hongwei Yuan,1– 3 Weiquan Li,1– 3 Wen Xiao,1– 3 Xiaoping Zhang1– 3 1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,
Tong J +6 more
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