Results 51 to 60 of about 827,322 (209)

Serotonin tranporter methylation and response to cognitive behaviour therapy in children with anxiety disorders [PDF]

, 2014
Anxiety disorders that are the most commonly occurring psychiatric disorders in childhood, are associated with a range of social and educational impairments and often continue into adulthood.
A Bittner, A Caspi, A Heils, AN Simmons, B Freeman, CCY Wong, D Wang, DA Cole, DHM Bodden, DR Nyholt, EL Kinnally, EL Kinnally, I Ouellet-Morin, J Belsky, J Cohen, J Piacentini, JL Hudson, JT Walkup, K Karg, K Wilhelm, KJ Lester, KN Månsson, KP Lesch, M Davies, M Van Ameringen, MB Stein, MH van Ijzendoorn, MW Coolen, N Perroud, O Doehrmann, PA Jones, R Bogdan, R Jaenisch, R Lowe, R Yehuda, RA Philibert, RM Rapee, S Cartwright-Hatton, S Sen, SC Messer, SE Taylor, SRH Beach, TC Eley, TC Eley, TH Ollendick, TM Ball, U Lueken, VL Ives-Deliperi, WK Silverman   +48 more
core   +2 more sources

How the Color Fades From Malus halliana Flowers: Transcriptome Sequencing and DNA Methylation Analysis

Frontiers in Plant Science, 2020
The flower color of many horticultural plants fades from red to white during the development stages, affecting ornamental value. We selected Malus halliana, a popular ornamental species, and analyzed the mechanisms of flower color fading using RNA ...
Mei-Ling Han, Jiao Yin, Yu-Heng Zhao, Xue-Wei Sun, Jia-Xin Meng, Jing Zhou, Ting Shen, Hou-Hua Li, Fan Zhang   +8 more
doaj   +1 more source

Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]

, 2011
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N., Gromoll, J., Haaf, T., Hahn, T., Schneider, E., Schorsch, M., Tresch, A., Zechner, Ulrich   +7 more
core   +1 more source

Folic acid restricts SARS-CoV-2 invasion by methylating ACE2

Frontiers in Microbiology, 2022
The current COVID-19 pandemic is motivating us to elucidate the molecular mechanism of SARS-CoV-2 invasion and find methods for decreasing its transmissibility. We found that SARS-CoV-2 could increase the protein level of ACE2 in mice.
Yuanzhou Zhang, Yechun Pang, Baiyin Xu, Xingshi Chen, Shunshun Liang, Jingying Hu, Xiaoying Luo   +6 more
doaj   +1 more source

Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis [PDF]

, 2011
Background\ud DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogenesis.
Chipman, J Kevin, Gong, Zhiyuan, Mirbahai, Leda, Williams, Timothy D, Zhan, Huiqing   +4 more
core   +4 more sources

PRMT5 function and targeting in cancer

Cell Stress, 2020
Protein methyl transferases play critical roles in numerous regulatory pathways that underlie cancer development, progression and therapy-response. Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic ...
Hyungsoo Kim, Ze’ev A. Ronai
doaj   +1 more source

Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain

Frontiers in Psychiatry, 2022
Although various susceptibility genes have been revealed to influence tobacco smoking, the underlying regulatory mechanisms between genetic variants and smoking are poorly understood. In this study, we investigated cis-expression quantitative trait loci (
Zhongli Yang, Jiekun Yang, Ying Mao, Ming D. Li, Ming D. Li   +4 more
doaj   +1 more source

Methylation status of Vitamin D receptor gene promoter in benign and malignant adrenal tumors [PDF]

, 2015
We previously showed a decreased expression of vitamin D receptor (VDR) mRNA/protein in a small group of adrenocortical carcinoma (ACC) tissues, suggesting the loss of a protective role of VDR against malignant cell growth in this cancer type ...
Cappellesso, Rocco, Fallo, Francesco, Fassina, Ambrogio, Guzzardo, Vincenza, Pilon, Catia, Rebellato, Andrea, Sasano, Hironobu, Urbanet, Riccardo   +7 more
core   +4 more sources

Aberrant p16INK4A methylation: Relation to viral related chronic liver disease and hepatocellular carcinoma

South Asian Journal of Cancer, 2014
Background: Hepatocellular carcinoma (HCC) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer related deaths.
Fatma A El-Mougy, Mohammed M Youssef, Dalia A Omran, Sahar A Sharaf, Hany H El-Sayed, Walaa A Rabie, Elghobary A Mohamed, Hany A Elghobary   +7 more
doaj   +1 more source

VEZF1 elements mediate protection from DNA methylation [PDF]

, 2010
There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states.
AC Bell, Adam G. West, AG West, AG West, AG West, Alan Hair, CD Lewis, CL Li, D Macleod, F Antequera, F Recillas-Targa, Gary Felsenfeld, H Gowher, Humaira Gowher, IG Lin, J Aitsebaomo, J Stalder, JA Wallace, Jacqueline Dickson, JH Chung, JH Chung, JP Issa, KS Wendt, L Valenzuela, Lisa Stubbs, M Brandeis, M Gaszner, M Marin, M Oki, MC Barton, Miklos Gaszner, MJ Pikaart, MM Suzuki, MN Prioleau, MN Prioleau, MS Turker, N Koyano-Nakagawa, PA Jones, PB Talbert, PD Jackson, PE Szabo, R Buckle, R Jaenisch, R Kellum, R Straussman, Ruslan Strogantsev, S Fan, S Huang, S Huang, S Yao, SP Clark, T Hashimshony, V Mutskov, VJ Mutskov, VK Rakyan   +54 more
core   +5 more sources