DNA methylation patterns and epigenetic memory.
The character of a cell is defined by its constituent proteins, which are the result of specific patterns of gene expression. Crucial determinants of gene expression patterns are DNA-binding transcription factors that choose genes for transcriptional ...
A. Bird
semanticscholar +1 more source
Tet Proteins Regulate Neutrophil Granulation in Zebrafish through Demethylation of socs3b mRNA
Summary: Tet proteins (Tet1/2/3) convert 5-methylcytosine (5mC) to 5-hydroxy-methylcytosine (5hmC), initiating the process of active demethylation to regulate gene expression.
Kelly M. Banks, Yahui Lan, Todd Evans
doaj
Plants regenerated from tissue culture contain stable epigenome changes in rice. [PDF]
Most transgenic crops are produced through tissue culture. The impact of utilizing such methods on the plant epigenome is poorly understood. Here we generated whole-genome, single-nucleotide resolution maps of DNA methylation in several regenerated rice ...
Bellizzi, Maria+8 more
core +2 more sources
ChemInform Abstract: Alkyl Methyl Carbonates as Methylating Agents. The O‐Methylation of Phenols. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PEROSA, Alvise+3 more
openaire +3 more sources
Zheng D, Bi X, Zhang T, et al. Psychol Res Behav Manag. 2020;13:997–1008. The authors have advised that there are several errors in the published paper which were introduced by the Editorial staff during the publication process ...
Zheng D+9 more
doaj
From trans-methylation to cytosine methylation: Evolution of the methylation hypothesis of schizophrenia [PDF]
The role of methylation in the history of psychiatry has traversed a storied path. The original trans-methylation hypothesis was proposed at a time when chlorpromazine had been synthesized but not yet marketed as an antipsychotic (Thorazine).
Erbo Dong+4 more
openaire +3 more sources
The DNA methylation inhibitor 5-aza-2’-deoxycytidine retards cell growth and alters gene expression in canine mammary gland tumor cells [PDF]
Disruption of gene expression by DNA methylation changes is widely involved in tumorigenesis. Here,to investigate DNA methylation changes in canine, we treated a canine mammary gland tumor cell line with a DNA methylation inhibitor, 5-aza-2 ...
Ito, Tsuyoshi, Kaneda, Masahiro
core +1 more source
Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been
Sven Thierbach+3 more
doaj +1 more source
Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias [PDF]
We have previously described gene expression changes during spontaneous immortalization of T-cells, thereby identifying cellular processes important for cell growth crisis escape and unlimited proliferation. Here, we analyze the same model to investigate
Borssén, Magnus+10 more
core +1 more source
On the electronic structure of methyl butyrate and methyl valerate [PDF]
AbstractWe present novel results of the analysis of the electronic structure of two aliphatic esters: methyl butyrate and methyl valerate. High-resolution photoabsorption spectra were collected and analyzed over the energy range 4.0–10.8 eV and showed for both the molecules not only a clear band of the HOMO to LUMO transition, but also vibronic ...
Smialek, Malgorzata A.+7 more
openaire +6 more sources