Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC. [PDF]
, 2006 The aim of this study is to develop a once-daily sustained release matrix tablet of ibuprofen using hydroxypropyl methylcellulose (HPMC) as release controlling factor and to evaluate drug release parameters as per various release kinetic models. In order
Tazeen, Jaweria +3 more
core +3 more sources
Role of cellulose family in fibril organization of collagen for forming 3D cancer spheroids: In vitro and in silico approach [PDF]
BioImpacts, 2021 Introduction: Cell aggregation of three-dimensional (3D) culture systems (the so-called spheroids) are designed as in vitro platform to represent more accurately the in vivo environment for drug discovery by using semi-solid media.
Elaheh Dalir Abdolahinia +5 more
doaj +1 more source
Pharmaceutics, 2023 Benign prostatic hyperplasia (BPH) affects about 90% of men whose ages are over 65. Tadalafil, a selective PDE-5 inhibitor, was approved by FDA for BPH, however, its poor aqueous solubility and bioavailability are considered major drawbacks.
Kawthar K. Abla +3 more
doaj +1 more source
Chemically Crosslinked Methylcellulose Substrates for Cell Sheet Engineering
Gels, 2021 Methylcellulose (MC) hydrogels have been successfully proposed in the field of cell sheet engineering (CSE), allowing cell detachment from their surface by lowering the temperature below their transition temperature (Tt).
Lorenzo Bonetti +2 more
doaj +1 more source
Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems
Pharmaceuticals, 2021 One of the major impediments to drug development is low aqueous solubility and thus poor bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the discovery pipeline are suffering from poor aqueous solubility and poor ...
Bharti Gupta +4 more
doaj +1 more source
Co-Delivery of Sustained Release Chondroitinase ABC-37 With Human iPSC-Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke. [PDF]
Adv Sci (Weinh)A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Letko Khait N +7 more
europepmc +2 more sources
Innovative composite films of chitosan, methylcellulose, and nanoparticles [PDF]
, 2011 Plastic is readily available and inexpensive, so it is becoming the main material for packaging. Unfortunately plastics do not biodegrade and, if reduced in small pieces, contaminate soil and waterways.
M. Piccinini +30 more
core +1 more source
Intralesional Trypan Blue-Colored Viscoelastic Injection for the Surgical Management of Dacryops
Türk Oftalmoloji Dergisi, 2012 During the surgical excision of dacryops which is a simple cyst of the lacrimal gland, a perforation of the thin wall of the cyst may lead to collapse of the lesion and complicate the surgery.
Gülşah Usta +3 more
doaj +1 more source
Methylcellulose–cellulose nanocrystal composites for optomechanically tunable hydrogels and fibers
, 2021 Chemical modification of cellulose offers routes for structurally and functionally diverse biopolymer derivatives for numerous industrial applications. Among cellulose derivatives, cellulose ethers have found extensive use, such as emulsifiers, in food ...
Nonappa, Jani +2 more
core +2 more sources
Indonesian Journal of Chemistry, 2014 The aim of this research is to explore the possibility of methylcellulose polymer to be used as wound dressing material prepared using electron beam technique.
Ambyah Suliwarno
doaj +1 more source